Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)

NCT05587621 · tracked via the Priya Life Science Germany tracker

Sponsor

Jena University Hospital

Phase

Not applicable

Started

2024-04-01

Last updated

2024-03-07

Condition(s) studied

ST Elevation Myocardial InfarctionNon-ST Elevation Myocardial InfarctionLDL-cholesterol

Investigational drug(s) / intervention(s)

statins, ezetimibe, bempedoic acid, evolocumab, alirocumab, inclisiran

statins, ezetimibe, bempedoic acid, evolocumab, alirocumab, inclisiran: dietary advice for low cholesterol food

Study summary

Intensive Lipid-Lowering Therapy guided by a cloud-based Software System (CLIMEDO GmbH) improves (European Society of Cardiolofgy/European Atherosclerosis Society) ESC/EAS-guideline recommended LDL-cholesterol target attainment and adherence in patients with ST-Elevation Myocardial (STEMI) and Non-ST-Elevation Myocardial Infarctions (NSTEMI).

Eligibility

Sex

ALL

Min age

18 Years

Max age

75 Years

Healthy volunteers

Inclusion Criteria: * patients with ST- and Non-ST-elevation myocardial infarctions Exclusion Criteria: * patient without informed concent * patients in cardiogenic shock * patients with contraindication to lipid-lowering therapy * patients on lipid-lowering medications on admission

Primary outcome measure(s)

LDL-C — 6 months
LDL-C target attainment (ESC/EAS dyslipidemia guidelines)

Trial sites (10)

Facility	City	Region
University Hospital Jena	Jena	Thuringia
Universitätsmedizin Berlin	Berlin	Germany
Universitätsklinikum Dresden	Dresden	Germany
Universitätsklinikum Essen	Essen	Germany
Universitätsklinikum Frankfurt	Frankfurt	Germany
Universitätsklinikum Freiburg	Freiburg im Breisgau	Germany
Universitätsklinikum Halle	Halle	Germany
Universitätsklinikum des Saarlandes	Homburg	Germany
Universitätsklinikum Leipzig	Leipzig	Germany
Universitätsklinikum Regensburg	Regensburg	Germany

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Other trials for the same condition

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05587621 on ClinicalTrials.gov ↗ ← All trials in Germany