Status
Study
Lead sponsor
Phase
Enrol
UK sites
Start
Recruiting
AstraZeneca
Phase 3
6,950
Ashton-under-Lyne, Basildon, Belfast, Birmingham, Brighton, Bristol, Cardiff, Clydebank
2026-08-24
Recruiting
CatalYm GmbH
Phase 2/3
518
Brighton, Cambridge, Dundee, Edinburgh, Guildford, Manchester, Newcastle upon Tyne
2026-04-16
Recruiting
Abbott Medical Devices
Not applicable
240
Brighton, Oxford
2026-03-31
Recruiting
Priovant Therapeutics, Inc.
Phase 2/3
342
Salford, Glasgow, Brighton, London, Wrexham
2026-03-19
Recruiting
AstraZeneca
Phase 2
124
Brighton, Guildford, Liverpool, London
2026-02-10
Recruiting
Novartis Pharmaceuticals
Phase 3
1,275
Brighton, Romford, Coventry, Glasgow, Leeds, London, Nottingham
2025-11-11
Recruiting
AstraZeneca
Phase 2
435
Belfast, Birmingham, Brighton, Cambridge, Dundee, Edinburgh, Exeter, Liverpool
2025-11-06
Recruiting
Olema Pharmaceuticals, Inc.
Phase 3
1,000
Brighton, London, Taunton, Guildford, Cardiff
2025-11-03
Recruiting
BioNTech SE
Phase 3
558
Brighton, Bristol, Cottingham, Edinburgh, Leeds, London, Oxford, Rhyl
2025-10-30
Recruiting
Novartis Pharmaceuticals
Phase 2
165
Brighton, Newcastle upon Tyne, Liverpool, London
2025-10-28
Recruiting
BeOne Medicines
Phase 3
500
Brighton, Canterbury, Norwich, Oxford, Roundhay, Salisbury
2025-09-04
Active, closed
Pfizer
Phase 3
208
Brighton, London
2025-07-31
Recruiting
BioNTech SE
Phase 3
480
Brighton, Bristol, Cambridge, Cottingham, Coventry, Edinburgh, Exeter, London
2025-06-10
Recruiting
Janssen Research & Development, LLC
Phase 3
600
Brighton, Cambridge, Canterbury, Colchester, Edinburgh, Liverpool, London, Plymouth
2025-06-04
Recruiting
Ceric Sàrl
Not applicable
1,180
Belfast, Brighton, Cambridge, Cottingham, Coventry, London, Newcastle upon Tyne, Sheffield
2025-05-15
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
605
Brighton, Fulham, Sutton, London, Manchester
2025-04-15
Recruiting
AstraZeneca
Phase 3
990
Bradford, Brighton, Cottingham, Glasgow, Halifax, Leeds, Portsmouth, Tyne and Wear
2025-03-18
Active, closed
AbbVie
Phase 3
468
Poole, Brighton, London, Thetford, Oxford
2025-02-10
By invitation
Pharvaris Netherlands B.V.
Phase 3
170
Birmingham, Brighton, Bristol, Cambridge, Frimley, London, Oxford, Plymouth
2025-02-01
Recruiting
BioNTech SE
Phase 2/3
1,580
Basildon, Bath, Brighton, Cardiff, Chelsea, Cottingham, Glasgow, Liverpool
2025-01-07
Active, closed
Gilead Sciences
Phase 3
609
Birmingham, Brighton, London
2024-10-09
Active, closed
Gilead Sciences
Phase 3
600
Brighton, Great Maze Pond, London
2024-10-08
Active, closed
Gilead Sciences
Phase 2
268
Birmingham, Brighton, Liverpool, London, Manchester
2024-10-07
Recruiting
Stemline Therapeutics, Inc.
Phase 3
4,220
Truro, Brighton, London, Cheltenham, Northwood, Blackpool, Preston, Livingston
2024-09-27
Active, closed
argenx
Phase 3
141
Brighton, Glasgow, Leeds, London, Southampton
2024-09-18
Active, closed
Boehringer Ingelheim
Phase 3
11,000
Antrim, Basildon, Belfast, Birmingham, Blackburn, Brighton, Bristol, Bury St Edmunds
2024-08-30
Active, closed
Microbiotica Ltd
Phase 1
41
Brighton, Cambridge, Glasgow, London, Manchester, Newcastle, Sutton
2024-08-28
Active, closed
Pfizer
Observational
450
Brighton, Dunfermline, Gloucester, Bath, Glasgow, London
2024-08-07
Recruiting
InnovHeart
Not applicable
30
Brighton
2024-04-04
By invitation
Abbott Medical Devices
Not applicable
1,500
Brighton, London, Newcastle upon Tyne
2024-03-15
Active, closed
Ipsen
Phase 3
759
Brighton, Brixton
2023-10-12
Recruiting
AbbVie
Phase 3
1,500
High Wycombe, Brighton, Gloucester, London, Oxford, Harrow, Salford
2023-10-11
Active, closed
Novartis Pharmaceuticals
Phase 3
383
Bristol, Brighton, Salford, Leicester, London, Nottingham
2023-07-06
Active, closed
Terumo Europe N.V.
Observational
3,000
Brighton, Lincoln, London, Londonderry, Newcastle, Newcastle upon Tyne, Plymouth, Worcester
2023-04-25
Recruiting
AstraZeneca
Phase 3
4,300
Brighton, Burton-on-Trent, Cambridge, Derby, Edinburgh, Guildford, Ipswich, Keighley
2023-03-31
Recruiting
VDyne, Inc.
Not applicable
120
Brighton, London
2023-03-01
Recruiting
Medtronic Cardiovascular
Not applicable
400
Brighton, Leeds, London
2023-02-07
Recruiting
Iperboreal Pharma Srl
Phase 3
170
Birmingham, Bradford, Brighton, Canterbury, London, Oxford, Sheffield, Stoke-on-Trent
2022-12-14
Active, closed
Gilead Sciences
Phase 2/3
689
Birmingham, Brighton, London
2022-08-16
Active, closed
Corcept Therapeutics
Phase 3
381
Brighton, Taunton, Cheltenham, London, Manchester, Northwood
2022-06-29
Active, closed
Occlutech International AB
Not applicable
450
Brighton, Belfast
2022-05-09
Recruiting
Scancell Ltd
Phase 1/2
168
Brighton, Cardiff, Edinburgh, Guildford, London, Manchester, Nottingham, Preston
2022-04-07
Active, closed
AstraZeneca
Phase 3
791
Birmingham, Brighton, Cardiff, Cheltenham, Edinburgh, High Heaton/Newcastle Upon Tyn, Leeds, London
2022-02-18
Recruiting
Colibri Heart Valve LLC
Not applicable
30
Brighton, London
2021-09-15
Recruiting
HighLife SAS
Not applicable
30
Brighton
2021-07-01
Active, closed
GlaxoSmithKline
Phase 3
40
Bath, Brighton, Cardiff, Coventry, Edinburgh, Leeds, London, Maidstone
2021-06-28
Recruiting
Penumbra Inc.
Observational
1,500
Brighton, Cardiff, London
2021-06-25
Active, closed
M.A. Med Alliance S.A.
Not applicable
3,326
Stoke-on-Trent, Bournemouth, Brighton, Bristol, Edinburgh, Glasgow, Leicester, Manchester
2021-05-15
Active, closed
Hoffmann-La Roche
Phase 3
1,188
Blackpool, Brighton, Cambridge, Cheltenham, London, Manchester, Northwood, Preston
2021-05-04
Active, closed
Medtronic Cardiac Ablation Solutions
Observational
545
Brighton, Coventry
2021-04-22
Active, closed
Abbott Medical Devices
Not applicable
200
Edinburgh, Brighton, Cambridge
2020-12-01
Active, closed
Eclipse Medical Ltd.
Not applicable
200
Brighton
2020-11-17
Active, closed
Boston Scientific Corporation
Not applicable
3,000
Brighton, Leicester, Oxford
2020-10-15
Active, closed
Hoffmann-La Roche
Phase 3
992
Brighton, Leicester, London, Maidstone, Peterborough, Plymouth, Sutton, Truro
2020-10-09
Recruiting
Smith & Nephew, Inc.
Observational
400
Manchester, Harpenden, Brighton, Burnley, Grantham, London, Bath, Hertford
2020-10-01
Active, closed
Janssen Research & Development, LLC
Phase 3
696
Bangor, Belfast, Brighton, Bristol, Great Maze Pond, Grimsby, Hillingdon, Inverness
2020-09-23
Active, closed
Abbott Medical Devices
Not applicable
2,650
Brighton
2020-07-07
Active, closed
Abbott Medical Devices
Not applicable
1,686
Southampton, Oxford, Brighton
2019-10-03
Active, closed
Tesaro, Inc.
Phase 3
785
Brighton, Cambridge, London, Truro
2019-07-18
Recruiting
HighLife SAS
Not applicable
120
Belfast, Brighton, Edinburgh, Leeds, Leicester, London, Oxford
2019-05-28
Active, closed
Travere Therapeutics, Inc.
Phase 3
406
Reading, Cambridge, Middlesbrough, Derby, Brighton, London, Manchester, Salford
2018-12-11
Active, closed
pharmaand GmbH
Phase 3
1,097
Canterbury, Cliftonville, Brighton, Bristol, Cambridge, Edinburgh, Lancaster, Leeds
2018-05-14
Active, closed
Medtronic Cardiovascular
Not applicable
128
Brighton, Leeds, London
2015-04