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Trackers› Clinical trials› South Dakota
Clinical trial register · United States · industry-sponsored

Clinical Trials in South Dakota, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9124 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 09 Oct 2026, 03:16 UTC
9124
Studies in scope
industry-sponsored, all four open statuses
4956
Recruiting now
open to new participants
2195
Lead sponsors
across recruiting studies
Top states
California 5298 Florida 4434 Illinois 2479 Georgia 2363 Arizona 2240
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Merck Sharp & Dohme LLC5 InGeneron, Inc.4 Amgen4 GlaxoSmithKline3 AstraZeneca3
State
California5298 Florida4434 Illinois2479 Georgia2363 Arizona2240
All 51 states
Target enrolment
to

Trials with a site in South Dakota

61 of 9124 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
GlaxoSmithKline
Phase 3
624
Florida, South Dakota, Utah
2026-09-11
Recruiting
GlaxoSmithKline
Phase 3
34
Alabama, Colorado, South Dakota
2026-06-25
Recruiting
xDot Access Management System Early Feasibility Study
NCT07464353Vascular Closure Devices
xDot Medical, Inc
Not applicable
30
Illinois, Minnesota, Oklahoma, South Dakota, Wisconsin
2026-06-16
Recruiting
AstraZeneca
Phase 3
150
California, Georgia, Illinois, Kentucky, Nevada, South Dakota, Tennessee, Texas
2026-06-15
Recruiting
Dompé Farmaceutici S.p.A
Phase 3
150
California, Florida, Massachusetts, Michigan, Missouri, New York, North Carolina, South Dakota
2026-06-02
Recruiting
NORM-HF Pivotal Study
NCT07574593Heart Failure, NYHA Class III Heart Failure, NYHA Class II Heart Failure
Foundry Innovation & Research 1, Limited (FIRE1)
Not applicable
800
California, Florida, New York, Ohio, Oklahoma, Pennsylvania, South Dakota
2026-05-29
Recruiting
Gilead Sciences
Phase 2
170
Connecticut, Massachusetts, Missouri, South Dakota, Virginia
2026-05-19
Recruiting
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
NCT07276711Aortic Valve Stenosis, Aortic Stenosis, Aortic Valve Disease
EmStop Inc
Not applicable
663
California, Florida, Louisiana, Michigan, North Carolina, South Dakota, Texas
2026-05-12
Recruiting
Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer
NCT07493512Metastatic Castration-resistant Prostate Cancer (mCRPC)
DrugXaluritamig
Amgen
Phase 1
40
Colorado, North Carolina, Ohio, Pennsylvania, South Dakota, Tennessee, Texas, Virginia
2026-04-28
Recruiting
Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
NCT07232030Heart Failure, Heart Failure NYHA Class II, Heart Failure NYHA Class III
CVRx, Inc.
Not applicable
2,500
Alabama, Florida, Missouri, Nebraska, Ohio, South Dakota, Tennessee, Texas
2026-04-24
Recruiting
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 3
420
Arizona, California, New Jersey, Ohio, Oregon, Pennsylvania, South Dakota
2026-04-17
Recruiting
Hoffmann-La Roche
Phase 2
80
California, Florida, Minnesota, South Dakota, Wisconsin
2026-04-07
Recruiting
MedtronicNeuro
Not applicable
256
Alabama, Idaho, Missouri, North Carolina, Ohio, Pennsylvania, South Carolina, South Dakota
2026-03-17
Recruiting
GlaxoSmithKline
Phase 3
456
Arkansas, California, Colorado, Florida, Louisiana, Oklahoma, Pennsylvania, South Dakota
2026-03-13
Recruiting
Ambulatory Long Length URodynamics Evaluation
NCT07425015Urology, Urinary Bladder, Overactive, Benign Prostatic Hyperplasia, Urodynamics
Bright Uro
Not applicable
101
Louisiana, Maryland, Missouri, Ohio, South Carolina, South Dakota, Texas, Washington
2026-02-17
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
170
California, Colorado, Florida, Kentucky, Missouri, New Jersey, Oregon, South Dakota
2026-01-29
Recruiting
Tempus AI
Observational
550
Iowa, Maryland, Missouri, Nevada, North Carolina, Ohio, Pennsylvania, South Dakota
2026-01-27
Recruiting
Merck Sharp & Dohme LLC
Phase 2
140
Florida, North Dakota, South Dakota
2025-12-19
Recruiting
Bristol-Myers Squibb
Phase 1/2
540
California, Pennsylvania, South Dakota, Texas, Utah, Washington
2025-10-15
Recruiting
Daiichi Sankyo
Phase 3
710
Florida, Indiana, Louisiana, North Carolina, Ohio, South Dakota, Texas
2025-09-30
Recruiting
Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease
NCT06989359IgAN, C3G, Complement-mediated Kidney Disease, IgA Nephropathy (IgAN)
ADARx Pharmaceuticals, Inc.
Phase 2
45
Florida, Iowa, Louisiana, Michigan, New York, Ohio, South Dakota, Texas
2025-08-28
Recruiting
Osheru Inc.
Not applicable
200
Florida, Minnesota, Pennsylvania, South Dakota, Wisconsin
2025-08
Recruiting
Study of BHV-1400 in IgA Nephropathy
NCT07054684IgA Nephropathy
Biohaven Therapeutics Ltd.
Phase 1
20
Connecticut, Florida, Georgia, Illinois, Indiana, Michigan, Missouri, South Dakota
2025-07-30
Recruiting
Imunon
Phase 3
500
Florida, Louisiana, Minnesota, Missouri, Oregon, South Dakota, Tennessee, Washington
2025-07-09
Active, closed
Amgen
Phase 1
29
California, Connecticut, Florida, Massachusetts, Missouri, North Dakota, Ohio, South Dakota
2025-05-16
Recruiting
Merck Sharp & Dohme LLC
Phase 2
90
Kentucky, Maryland, North Dakota, Pennsylvania, South Dakota
2025-03-30
Recruiting
A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors
NCT06803680Advanced Solid Tumor, Metastatic Solid Tumor
BeOne Medicines
Phase 1
90
Florida, Pennsylvania, South Dakota, Texas, Washington
2025-03-18
Active, closed
An Ophthalmic Safety Study in Patients With Breast Cancer
NCT06767462Ophthalmic Safety in Patients With Breast Cancer
AstraZeneca
Observational
160
California, Iowa, North Carolina, Pennsylvania, South Dakota, Tennessee, Texas
2025-03-05
Recruiting
Takeda
Phase 3
396
California, Colorado, Florida, Indiana, Kentucky, New York, South Carolina, South Dakota
2025-01-02
Recruiting
Rakuten Medical, Inc.
Phase 3
412
California, Florida, Kentucky, Pennsylvania, Rhode Island, South Dakota, Texas
2024-12-24
Recruiting
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 2
25
Colorado, Massachusetts, South Dakota, Texas
2024-11-19
Active, closed
Regeneron Pharmaceuticals
Phase 2
120
California, Illinois, Michigan, Ohio, Oregon, Rhode Island, South Dakota, Tennessee
2024-11-18
Active, closed
Bristol-Myers Squibb
Phase 1
213
Arizona, California, Michigan, South Dakota, Texas
2024-10-10
Recruiting
Amgen
Phase 1
220
California, Illinois, Michigan, South Dakota, Texas, Washington
2024-10-07
Recruiting
Melodi Matrix™ in Breast Reconstruction
NCT06027996Breast Reconstruction
Melodi Health, Inc.
Not applicable
702
California, Michigan, Minnesota, New York, Ohio, Pennsylvania, South Carolina, South Dakota
2024-08-09
Recruiting
AstraZeneca
Phase 2
80
California, Connecticut, Florida, Iowa, Kentucky, Maryland, Michigan, South Dakota
2024-07-16
Recruiting
Study of WAL0921 in Patients With Glomerular Kidney Diseases
NCT06466135Diabetic Nephropathies, Primary Focal Segmental Glomerulosclerosis, Minimal Change Disease, Primary Immunoglobulin A Nephropathy
Walden Biosciences
Phase 2
96
California, Colorado, Florida, Georgia, Illinois, South Dakota, Texas
2024-07-02
Active, closed
A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors
NCT06257264Breast Cancer, Small Cell Lung Cancer, Ovarian Cancer, Gastric Cancer
DrugsBGB-43395·Fulvestrant
BeiGene
Phase 1
103
California, Florida, Missouri, New Jersey, South Dakota, Texas
2024-03-11
Recruiting
Pliant Therapeutics, Inc.
Phase 1
124
Connecticut, Georgia, Michigan, Missouri, New Jersey, New York, North Carolina, South Dakota
2023-08-30
Active, closed
Hoffmann-La Roche
Phase 2
83
California, New York, North Carolina, South Dakota
2023-07-18
Active, closed
USWM CT, LLC
Phase 2
66
Arizona, California, Georgia, Michigan, New Jersey, Ohio, Oklahoma, South Dakota
2023-06-26
Active, closed
Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration
NCT06087458Age-Related Macular Degeneration, Geographic Atrophy, Non-neovascular AMD, Non-neovascular Age-related Macular Degeneration
DrugVOY-101
Perceive Biotherapeutics, Inc.
Phase 1/2
60
Arizona, California, Massachusetts, Missouri, New Jersey, Oregon, South Dakota, Texas
2023-06-21
Recruiting
Pounce™ Thrombectomy System Retrospective Registry
NCT05868161Peripheral Arterial Disease, Acute Limb Ischemia
SurModics, Inc.
Observational
500
Illinois, Indiana, Louisiana, Minnesota, Ohio, South Carolina, South Dakota, Tennessee
2023-04-18
Recruiting
BioMarin Pharmaceutical
Observational
170
California, Maryland, North Carolina, Ohio, South Dakota, Texas, Wisconsin
2023-02-21
Active, closed
Amgen
Phase 1
184
California, Delaware, Michigan, New Jersey, New York, North Carolina, South Dakota, Washington
2022-08-24
Active, closed
Cloudbreak Therapeutics, LLC
Phase 3
660
Alabama, Arizona, California, Florida, Kentucky, Nevada, South Dakota, Texas
2022-06-30
Active, closed
Merck Sharp & Dohme LLC
Phase 1
70
South Dakota, Texas
2022-06-16
By invitation
InGeneron, Inc.
Not applicable
246
Arizona, California, Florida, Georgia, Louisiana, South Dakota, Texas
2022-01-01
Active, closed
Boehringer Ingelheim
Phase 1
151
Arizona, California, North Carolina, South Dakota, Texas
2021-10-18
Active, closed
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP
NCT04971226Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive
DrugsBosutinib·Asciminib·ABL001·Nilotinib
Novartis Pharmaceuticals
Phase 3
405
Colorado, Florida, Kentucky, Massachusetts, North Carolina, Oregon, South Dakota, Tennessee
2021-10-06
Recruiting
Perform Humeral System Study
NCT05067543Osteoarthritis Shoulder, Avascular Necrosis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Tear Arthropathy
Stryker Trauma and Extremities
Observational
300
Kentucky, Minnesota, Missouri, Ohio, South Dakota, Utah
2021-09-12
Active, closed
CYPRESS Efficacy and Safety Study Extension
NCT04947735Juvenile Myopia, Myopia
SightGlass Vision, Inc.
Not applicable
200
California, Florida, Kansas, Louisiana, Missouri, New York, South Dakota, Tennessee
2021-07-19
Active, closed
Persona Ti-Nidium Post-Market Clinical Follow-up
NCT04817969Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
Zimmer Biomet
Not applicable
240
Colorado, Maryland, Mississippi, New Mexico, North Carolina, Pennsylvania, South Dakota
2021-06-01
Active, closed
Geron Corporation
Phase 3
327
California, Connecticut, Florida, Kentucky, New York, North Carolina, Ohio, South Dakota
2021-04-12
Active, closed
ImmunityBio, Inc.
Phase 2
328
California, New Jersey, South Dakota
2020-07-21
Active, closed
Sequana Medical N.V.
Not applicable
110
Arizona, California, Massachusetts, Minnesota, North Carolina, Pennsylvania, South Carolina, South Dakota
2019-09-16
Active, closed
InGeneron, Inc.
Not applicable
168
Arizona, California, Florida, Georgia, Louisiana, Michigan, North Dakota, South Dakota
2019-05-13
Recruiting
InGeneron, Inc.
Not applicable
40
Florida, South Dakota
2018-12-07
Active, closed
Healing Osteoarthritic Joints in the Wrist With Adult ADRCs
NCT03503305Osteoarthritis of the Wrist
InGeneron, Inc.
Not applicable
40
South Dakota, Texas
2018-11-21
Active, closed
SightGlass Vision, Inc.
Not applicable
266
California, Florida, Kansas, Louisiana, Missouri, New York, South Dakota, Tennessee
2018-07-16
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
370
Colorado, Illinois, Massachusetts, New York, North Dakota, South Dakota, Texas
2015-03-19
Rows per page Showing 1–61 of 61
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 9 October 2026. https://priyalifescience.com/clinical-trials-usa/state/south-dakota

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,124 studies in total at the last sync on 09 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 61 of those studies with a site in South Dakota.

How many clinical trials are recruiting in South Dakota?

39 of the 61 studies on this page are recruiting new participants as of the 09 Oct 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 21 are active but closed to new participants, and 1 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (South Dakota), 61 studies
PhaseStudiesRecruitingShare
Not applicable16926.2%
Phase 3131021.3%
Phase 212819.7%
Phase 111518%
Observational548.2%
Phase 1/2436.6%

Most active sponsors

Lead sponsors with the most studies (South Dakota)
Lead sponsorStudiesRecruiting
Merck Sharp & Dohme LLC54
Amgen42
InGeneron, Inc.41
AstraZeneca32
GlaxoSmithKline33
Bristol-Myers Squibb21
Hoffmann-La Roche21
SightGlass Vision, Inc.20
ADARx Pharmaceuticals, Inc.11
BeiGene10
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.