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Trackers› Clinical trials› Breast Cancer
Clinical trial register · Netherlands

Breast Cancer Trials in Netherlands, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Netherlands and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 3175 matching records held by the registry are in this view. Synced 13 Nov 2026, 03:17 UTC
3175
Studies in scope
all four open statuses
1789
Recruiting now
open to new participants
601
Lead sponsors
across recruiting studies
Top sites
Amsterdam 31 Maastricht 13 Utrecht 9 Rotterdam 8 Leiden 8
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
The Netherlands Cancer Institute12 UMC Utrecht5 AstraZeneca4 Maastricht University Medical Center4 Amsterdam UMC, location VUmc3 Eli Lilly and Company3 Olema Pharmaceuticals, Inc.2 European Organisation for Research and Treatment of Cancer - EORTC2 Pfizer2 Isabelle Henskens2 University Medical Center Groningen2 SPCTR1 Comprehensive Cancer Centre The Netherlands1 Bristol-Myers Squibb1 St. Antonius Hospital1 UNICANCER1 Reinier de Graaf Groep1 Stemline Therapeutics, Inc.1 Hoffmann-La Roche1 University Hospital, Basel, Switzerland1 Novartis Pharmaceuticals1 C.H. van Gils1 Borstkanker Onderzoek Groep1 XEOS Medical1 Daiichi Sankyo1 Show all 29
Site location
Amsterdam31 Maastricht13 Utrecht9 Rotterdam8 Leiden8 The Hague8 Nijmegen7 Alkmaar7 Groningen6 Breda6 Apeldoorn5 Deventer5 Arnhem5 's-Hertogenbosch5 Delft5 Dordrecht4 Almelo4 Leeuwarden3 Zwolle3 Amersfoort3 Zaandam3 Beverwijk3 Uden2 Hengelo2 Venlo2 Show all 44
All 44 locations
Target enrolment
to

Breast Cancer trials in Netherlands

59 of 3175 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Netherlands
Start
Recruiting
Autologous Fat Grafting for Total Breast Reconstruction in Irradiated Breast Cancer Patients
NCT07641985Breast Cancer, Breast Reconstruction, Breast Reconstruction After Mastectomy, Breast Cancer Radiation
Maastricht University Medical Center
Not applicable
280
Maastricht
2026-07-01
Not yet open
University Medical Center Groningen
Not applicable
8
Groningen
2026-06-01
Recruiting
Multicenter Cardiac Decision Impact Study in People With Breast Cancer
NCT07703033Breast Cancer, Cardiovascular (CV) Risk, Coronary Artery Calcifications
UMC Utrecht
Not applicable
1,000
Amsterdam, Utrecht
2026-04-20
Recruiting
Spectral Cancer Tissue Recognition - I
NCT07459062Margin Assessment, Breast Cancer
SPCTR
Observational
100
Groningen, Utrecht
2026-01-12
Recruiting
UNICANCER
Phase 3
3,902
Arnhem, Hilversum, Hoofddorp, Leeuwarden, Leiden, Venlo
2025-12-18
Recruiting
XEOS Medical
Observational
850
Groningen
2025-11-19
Recruiting
The Netherlands Cancer Institute
Observational
100
Enschede, Amsterdam, Breda, Deventer, Groningen, Maastricht, Nijmegen, Rotterdam
2025-11-06
Recruiting
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
NCT07085767Breast Cancer, Locally Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer
DrugsPalazestrant·Ribociclib·Letrozole
Olema Pharmaceuticals, Inc.
Phase 3
1,000
Apeldoorn, Maastricht, Amsterdam
2025-11-03
Recruiting
The Netherlands Cancer Institute
Not applicable
100
Amsterdam
2025-10-14
Recruiting
Contrast-enhanced Ultrasound for Sentinel Node Detection
NCT07310758Melanoma, Breast Cancer, Head & Neck Cancer
DrugSonazoid
The Netherlands Cancer Institute
Phase 2/3
91
Amsterdam
2025-09-18
Recruiting
18F-FDG Versus 68Ga-FAPI-46 as PET Tracer in ER-positive Breast Cancer.
NCT06335069Breast Cancer, Breast Neoplasms, Breast Diseases
Maastricht University Medical Center
Phase 2
20
Maastricht
2025-09-01
Recruiting
Relay Therapeutics, Inc.
Phase 3
540
Maastricht, Nijmegen, Sittard, The Hague
2025-08-26
Recruiting
Breast Reconstruction and Radiotherapy
NCT07178886Breast Cancer
Janine M. Simons MD PhD
Observational
750
Rotterdam
2025-08-22
Recruiting
Pfizer
Phase 3
400
Hilversum, Schiedam
2025-08-05
Recruiting
Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer
NCT07146295Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Sentinel Lymph Node Detection, Sentinel Lymph Node
DrugIndocyanine Green
Isabelle Henskens
Not applicable
1,760
Alkmaar, Hengelo, Hoofddorp, Hoorn, Leiden, Nijmegen, Utrecht
2025-04-18
Recruiting
European Organisation for Research and Treatment of Cancer - EORTC
Not applicable
302
Deventer, Nijmegen
2025-04-15
Recruiting
Bristol-Myers Squibb
Phase 1/2
416
Leiden, Amsterdam
2025-02-04
Active, closed
Pfizer
Phase 3
1,035
Breda, Amersfoort
2025-01-06
Recruiting
C.H. van Gils
Not applicable
36,000
Utrecht
2024-11-11
Recruiting
UMC Utrecht
Not applicable
140
Utrecht
2024-10-08
Recruiting
REDucing Hot FLASHes in Women Using Endocrine Therapy.
NCT06106529Breast Cancer, Hot Flash Due to Medication
DrugsOxybutynin·Venlafaxine
Reinier de Graaf Groep
Phase 3
260
Delft
2024-10-03
Active, closed
Stemline Therapeutics, Inc.
Phase 3
4,556
Tilburg, Dordrecht, The Hague, Eindhoven
2024-09-27
Active, closed
Novartis Pharmaceuticals
Phase 1/2
20
Delft
2024-08-14
Recruiting
Maastricht University Medical Center
Not applicable
11
Maastricht
2024-05-27
Active, closed
The OPBC-07/microNAC Study
NCT06529302Breast Cancer
University Hospital, Basel, Switzerland
Observational
2,000
Amsterdam
2024-05-15
Recruiting
The Netherlands Cancer Institute
Not applicable
31
Amsterdam
2024-04-12
Recruiting
Amsterdam UMC, location VUmc
Observational
500
Amsterdam
2024-02-01
Recruiting
Daiichi Sankyo
Phase 3
250
Amsterdam, Breda, Leeuwarden, Leiden, Maastricht, The Hague, Tilburg, Uden
2023-12-30
Recruiting
The Netherlands Cancer Institute
Phase 1
30
Amsterdam
2023-12-18
Active, closed
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
NCT06016738Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer
DrugsPalazestrant·Exemestane·Anastrozole·Letrozole
Olema Pharmaceuticals, Inc.
Phase 3
510
Amsterdam, Rotterdam
2023-11-16
Active, closed
St. Antonius Hospital
Not applicable
493
's-Hertogenbosch, Almere Stad, Amsterdam, Delft, Dirksland, Maastricht, Rotterdam, The Hague
2023-06-08
Recruiting
Eli Lilly and Company
Phase 1/2
880
Amsterdam, Rotterdam
2023-04-17
Recruiting
UMC Utrecht
Not applicable
20
Bilthoven
2023-04-01
By invitation
Effectiveness of Personalized Surveillance and Aftercare for Breast Cancer
NCT05975437Breast Cancer, Breast Cancer Female, Survivorship
Comprehensive Cancer Centre The Netherlands
Observational
1,040
Apeldoorn, Arnhem, 's-Hertogenbosch, Uden, Alkmaar, Hengelo, Zwolle, Dordrecht
2023-03-06
Recruiting
The Netherlands Cancer Institute
Not applicable
595
Amsterdam
2022-10-07
Recruiting
Developing Breast (Cancer) Organoids
NCT05317221Breast Cancer
Maastricht Radiation Oncology
Observational
60
Maastricht
2022-09-01
Recruiting
Amsterdam UMC, location VUmc
Not applicable
100
Almere Stad, Amstelveen, Amsterdam, Nijmegen, Zaandam
2022-08-24
Recruiting
Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study)
NCT07362485Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Sentinel Lymph Node Detection, Sentinel Lymph Node
Isabelle Henskens
Not applicable
90
Zwolle, Utrecht
2022-08-22
Recruiting
AstraZeneca
Phase 1/2
460
Amsterdam
2021-10-18
Active, closed
AstraZeneca
Phase 3
732
Amsterdam, Rotterdam, Venlo
2021-10-18
Active, closed
Amsterdam UMC, location VUmc
Not applicable
15
Amsterdam
2021-10-11
Active, closed
AstraZeneca
Phase 3
506
Maastricht, The Hague
2021-06-22
Recruiting
Maastricht University Medical Center
Observational
549
's-Hertogenbosch, Alkmaar, Amsterdam, Apeldoorn, Arnhem, Beverwijk, Bilthoven, Breda
2020-07-16
Active, closed
The SONImage Study
NCT04125277Breast Cancer
The Netherlands Cancer Institute
Not applicable
100
Amsterdam
2019-12-05
Recruiting
The Netherlands Cancer Institute
Phase 2
80
Amsterdam
2019-10-04
Active, closed
Borstkanker Onderzoek Groep
Phase 2
462
's-Hertogenbosch, Alkmaar, Almelo, Amersfoort, Amstelveen, Amsterdam, Apeldoorn, Arnhem
2019-02-27
Recruiting
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
NCT04075305Oncology, Breast Cancer, Prostate Cancer, Gynecologic Cancer
UMC Utrecht
Observational
8,000
Amsterdam, Deventer, Leeuwarden, Nijmegen, Utrecht
2019-02-01
Active, closed
Eli Lilly and Company
Phase 3
5,637
Maastricht, Amsterdam, Dordrecht, The Hague
2017-07-12
Active, closed
The Netherlands Cancer Institute
Phase 3
174
Enschede, Amsterdam, Groningen, Leiden, Maastricht, Nijmegen, Rotterdam, Utrecht
2017-01-25
Active, closed
Hoffmann-La Roche
Phase 2
534
Leiden
2015-11-19
Active, closed
Alliance Foundation Trials, LLC.
Phase 3
5,796
Eindhoven, Geleen, Nieuwegein, The Hague, Zaandam, Zwolle
2015-08
Active, closed
Eli Lilly and Company
Phase 3
493
The Hague, Leiden
2014-11-06
Active, closed
AstraZeneca
Phase 3
1,837
Amsterdam, Breda, Geleen, Leiden, Maastricht, Rotterdam, Zaandam
2014-04-22
Active, closed
The Netherlands Cancer Institute
Phase 3
437
's-Hertogenbosch, Alkmaar, Almelo, Amsterdam, Beverwijk, Breda, Delft, Deventer
2013-12-21
Recruiting
UMC Utrecht
Observational
10,000
Almelo, Leiderdorp, Nieuwegein, Utrecht
2013-10
Active, closed
The Netherlands Cancer Institute
Phase 2
304
Alkmaar, Almelo, Amersfoort, Amsterdam, Apeldoorn, Arnhem, Bergen op Zoom, Beverwijk
2013-07
Active, closed
European Organisation for Research and Treatment of Cancer - EORTC
Observational
200
Amsterdam
2010-12
Active, closed
The Netherlands Cancer Institute
Phase 2/3
310
Alkmaar, Amsterdam, Delft, Deventer, Dordrecht, Ede, Haarlem, Heerlen
2010-01
By invitation
University Medical Center Groningen
Observational
10,000
Groningen
2008-01-01
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Dutch investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 14 November 2026. https://priyalifescience.com/clinical-trials-netherlands/condition/breast-cancer

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Netherlands and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 3,175 studies in total at the last sync on 13 Nov 2026, 03:17 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 59 of those studies listing the condition Breast Cancer.

How many Breast Cancer trials are recruiting in Netherlands?

35 of the 59 studies on this page are recruiting new participants as of the 13 Nov 2026, 03:17 UTC sync. A further 1 have not yet opened recruitment, 21 are active but closed to new participants, and 2 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Breast Cancer), 59 studies
PhaseStudiesRecruitingShare
Not applicable171328.8%
Phase 317628.8%
Observational13922%
Phase 2528.5%
Phase 1/2436.8%
Phase 2/3213.4%
Phase 1111.7%

Most active sponsors

Lead sponsors with the most studies (Breast Cancer)
Lead sponsorStudiesRecruiting
The Netherlands Cancer Institute127
UMC Utrecht55
AstraZeneca41
Maastricht University Medical Center44
Amsterdam UMC, location VUmc32
Eli Lilly and Company31
European Organisation for Research and Treatment of Cancer - EORTC21
Isabelle Henskens22
Olema Pharmaceuticals, Inc.21
Pfizer21
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.