🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Contributor sign in
Latest
Priya Life Science Clinical trial register
TrackersDrugsComparisonsAPI
Trackers› Clinical trials› Cologne
Clinical trial register · Germany

Clinical Trials in Cologne, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

Download CSV
Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5051 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:51 UTC
5051
Studies in scope
all four open statuses
2882
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1584 Hamburg 889 Essen 760 Dresden 707 Heidelberg 627
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca48 Novartis Pharmaceuticals29 University of Cologne25 Janssen Research & Development, LLC21 Bristol-Myers Squibb21
Site location
Berlin1584 Hamburg889 Essen760 Dresden707 Heidelberg627
All 635 locations
Target enrolment
to

Trials with a site in Cologne

612 of 5051 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Recruiting
Study to Assess Safety of HDP-101 in Patients With Relapsed Refractory Multiple Myeloma
NCT04879043Multiple Myeloma, Plasma Cell Disorder
DrugHDP-101
Heidelberg Pharma AG
Phase 1/2
78
Berlin, Chemnitz, Cologne, Hamburg, Heidelberg, Kiel, Lübeck, Mainz
2022-02-07
Active, closed
A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease
NCT05197049Crohn Disease
DrugsGuselkumab 1·Guselkumab 2·Guselkumab 3
Janssen Research & Development, LLC
Phase 3
350
Berlin, Braunschweig, Cologne, Dachau, Duisburg, Halle, Hanover, Jerichow
2022-01-19
Active, closed
A Single-arm Trial of Atezolizumab/Platinum/Etoposide for the Treatment of Advanced Large-cell Neuroendocrine Cancer of the Lung
NCT05470595Large Cell Neuroendocrine Carcinoma of the Lung
DrugAtezolizumab
Technische Universität Dresden
Phase 2
67
Berlin, Cologne, Dresden, Frankfurt am Main, Gauting, Großhansdorf, Halle, Heidelberg
2022-01-18
Recruiting
The "Global Paradise System" Registry
NCT05027685Hypertension
ReCor Medical, Inc.
Observational
3,000
Ahrweiler, Bad Krozingen, Berlin, Coburg, Cologne, Detmold, Dresden, Düsseldorf
2022-01-13
Recruiting
A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
NCT05118789Locally Advanced Solid Tumor, Metastatic Solid Tumor
Nuvalent Inc.
Phase 1/2
359
Cologne
2022-01-04
Active, closed
Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-positive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor.
NCT05038735Breast Cancer
DrugsAlpelisib·Fulvestrant
Novartis Pharmaceuticals
Phase 3
210
Cologne, Augsburg, Berlin, Essen, Lübeck
2021-12-17
Active, closed
Venetoclax in Addition to Blinatumomab in Adult Patients With Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)
NCT05182385ALL, Recurrent, Adult
DrugsVenclyxto·Blinatumomab·Venetoclax
Goethe University
Phase 1/2
30
Tübingen, Ulm, Frankfurt am Main, Dresden, Berlin, Cologne, Düsseldorf, Erlangen
2021-12-15
Active, closed
From the Emergency Department Directly to Ablation of Atrial Fibrillation Study
NCT05294445Atrial Fibrillation (AF)
Asklepios proresearch
Not applicable
350
Bad Nauheim, Berlin, Cologne, Düsseldorf, Frankfurt, Giessen, Hamburg, Hamburg-Nord
2021-12-15
Active, closed
BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)
NCT04982393Primary Hyperoxaluria Type 1
Alnylam Pharmaceuticals
Observational
207
Berlin, Cologne, Hamburg
2021-12-13
Active, closed
Prognostic Role of Circulating Tumor DNA in Resectable Pancreatic Cancer
NCT04246203Pancreas Cancer
Ludwig-Maximilians - University of Munich
Observational
200
Munich, Berlin, Cologne, Hamburg, Ulm
2021-12-12
Active, closed
A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC)
NCT05060016Relapsed/Refractory Small Cell Lung Cancer
DrugTarlatamab
Amgen
Phase 2
222
Cologne, Großhansdorf, Würzburg
2021-12-01
Recruiting
HIV Resistance, Molecular Epidemiology and New Treatment Strategies in the Eastern European Region and in Russia
NCT06127290HIV-1-infection
Euresist Network GEIE
Observational
200
Cologne
2021-12-01
Recruiting
A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma
NCT05160584Relapsed/Refractory Multiple Myeloma
Janssen Pharmaceutica N.V., Belgium
Observational
300
Berin, Cologne, Dresden, Hamburg, Hamm, Heidelberg, Karlsruhe, Leipzig
2021-11-18
Recruiting
Additional Chemotherapy for EGFRm Patients with the Continued Presence of Plasma CtDNA EGFRm At Week 3 After Start of Osimertinib 1st-line Treatment (PACE-LUNG)
NCT05281406NSCLC Stage IIIB, NSCLC Stage IV
DrugsTagrisso·Osimertinib·Pemetrexed·Cisplatin
Goethe University
Phase 2
50
Berlin, Cologne, Dresden, Essen, Frankfurt, Gauting, Georgsmarienhütte, Göttingen
2021-11-12
Active, closed
A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations
NCT05048797Locally Advanced or Metastatic Non-Small Cell Lung Cancer
DrugsTrastuzumab deruxtecan·Pemetrexed·Cisplatin·Carboplatin
AstraZeneca
Phase 3
454
Cologne, Dresden, Mainz, München, Oldenburg
2021-10-28
Active, closed
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
NCT04861259Atypical Hemolytic Uremic Syndrome
DrugCrovalimab
Hoffmann-La Roche
Phase 3
83
Cologne, Essen, Hanover
2021-10-22
Active, closed
Low-dose Atropine for Myopia Control in Children
NCT03865160Myopia, Progressive
DrugAtropine eye
University Eye Hospital, Freiburg
Phase 2/3
302
Ahaus, Bonn, Cologne, Erlangen, Essen, Freiburg im Breisgau, Göttingen, Hamburg
2021-10-19
Active, closed
A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
NCT04895696Systemic Lupus Erythematosus
Beeline Medicines Corporation
Phase 2
248
Cologne, Berlin, Essen, Freiburg im Breisgau
2021-10-11
Recruiting
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
NCT05006716B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma
DrugTacabrutideg
BeOne Medicines
Phase 1/2
645
Cologne, Dresden, Leipzig, Lübeck, Mainz, München, Ulm
2021-09-13
Active, closed
A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)
NCT04765059Non-small Cell Lung Cancer
DrugCarboplatin
AstraZeneca
Phase 3
98
Berlin, Cologne, Hanover, München
2021-09-12
Active, closed
RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation
NCT05036018Aortic Valve Stenosis
Leipzig Heart Science gGmbH
Not applicable
836
Bad Berka, Bad Oeynhausen, Cologne, Dortmund, Giessen, Leipzig, München, Tübingen
2021-08-30
Active, closed
A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice
NCT05049798Arthritis, Psoriatic
DrugsIL-17i·Tremfya·Guselkumab
Janssen Pharmaceutica N.V., Belgium
Observational
1,314
Amberg, Bayreuth, Berlin, Cologne, Düsseldorf, Erfurt, Frankfurt, Halle
2021-08-25
Recruiting
A Registry Study on HIV-related Lymphoma
NCT05231135AIDS Related Lymphoma, HIV Related Lymphoma
Rotkreuzklinikum München gGmbH
Observational
300
Munich, Cologne
2021-08-25
Active, closed
STOP Persistent AF PAS
NCT05005949Persistent Atrial Fibrillation
Medtronic Cardiac Ablation Solutions
Observational
400
Cologne, Frankfurt am Main, München
2021-08-19
Recruiting
Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients
NCT04844866Diffuse Large B-cell Lymphoma
Miltenyi Biomedicine GmbH
Phase 2
213
Augsburg, Bochum, Cologne, Erlangen, Essen, Hamburg, Heidelberg, Leipzig
2021-08-18
Recruiting
Treatment Of Steroid-Refractory Acute Graft-versus-host Disease With Mesenchymal Stromal Cells Versus Best Available Therapy
NCT04629833Steroid-refractory Acute Graft-versus-host Disease
DrugMC0518
medac GmbH
Phase 3
210
Munich, Würzburg, Frankfurt am Main, Hanover, Cologne, Essen, Münster, Dresden
2021-08-16
By invitation
Selatogrel Outcome Study in Suspected Acute Myocardial Infarction
NCT04957719Acute Myocardial Infarction
Viatris Innovation GmbH
Phase 3
25,000
Bad Krozingen, Bad Oeynhausen, Berlin, Bonn, Cologne, Dortmund, Dresden, Hamburg
2021-08-14
Recruiting
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
NCT05003986Focal Segmental Glomerulosclerosis, Minimal Change Disease, Immunoglobulin A Nephropathy, IgA Vasculitis
DrugSparsentan
Travere Therapeutics, Inc.
Phase 2
67
Cologne, Hamburg, Heidelberg
2021-08-12
Active, closed
Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma
NCT04674683Unresectable or Metastatic Melanoma, Progressive Brain Metastasis
DrugsChidamide·Nivolumab
HUYABIO International, LLC.
Phase 3
450
Berlin, Cologne, Dresden, Erfurt, Essen, Freiburg im Breisgau, Heidelberg, Leipzig
2021-08-12
Recruiting
European Disease Registry on Retinopathy of Prematurity (ROP)
NCT04939571Retinopathy of Prematurity
University Medicine Greifswald
Observational
3,000
Aachen, Berlin, Bonn, Braunschweig, Chemnitz, Cologne, Cottbus, Düsseldorf
2021-08-06
Active, closed
Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin
NCT04960709Muscle Invasive Bladder Cancer
DrugsEnfortumab Vedotin·Tremelimumab·Durvalumab
AstraZeneca
Phase 3
712
Bielefeld, Bochum, Cologne, Düsseldorf, Giessen, Hanover, Herne, Magdeburg
2021-08-05
Active, closed
Chemotherapy-Free pCR-Guided Strategy With Trastuzumab-pertuzumab and T-DM1 in HER2-positive Early Breast Cancer
NCT04733118Early Breast Cancer
MedSIR
Phase 2
393
Cologne, Duisburg, Essen, Manheim, Potsdam
2021-08-05
Active, closed
Pulmonary Embolism International THrOmbolysis Study-3
NCT04430569Pulmonary Embolism
DrugAlteplase
Assistance Publique - Hôpitaux de Paris
Phase 3
800
Bad Krozingen, Berlin, Cologne, Dresden, Düsseldorf, Freiburg im Breisgau, Greifswald, Hanover
2021-08-04
Recruiting
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
NCT04817618C3G
DrugIptacopan
Novartis Pharmaceuticals
Phase 3
98
Cologne, Aachen, Erlangen, Essen, Hamburg, Hanover, Heidelberg, Mainz
2021-07-28
By invitation
A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus
NCT04976322Systemic Lupus Erythematosus
UCB Biopharma SRL
Phase 3
760
Cologne, Freiburg im Breisgau, Herne, Leipzig, Tübingen, Vogelsang-gommern
2021-07-27
Recruiting
German Cardiac Arrest Registry
NCT05142124Out-of-hospital Cardiac Arrest
Leipzig Heart Science gGmbH
Observational
400
Berlin, Bad Friedrichshall, Bonn, Bremen, Cologne, Dresden, Düsseldorf, Essen
2021-07-21
Recruiting
A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications
NCT04877288Renal Allograft Recipients
DrugsCyclosporine A·Belatacept·Mycophenolate Mofetil·Tacrolimus
Bristol-Myers Squibb
Phase 3
102
Essen, Cologne, Hamburg, Heidelberg
2021-07-21
Active, closed
A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
NCT04961567Lupus Erythematosus, Systemic
DrugLitifilimab
Biogen
Phase 3
562
Göttingen, Hanover, Cologne, Münster, Mainz
2021-07-16
Active, closed
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment
NCT04908189Psoriatic Arthritis
DrugsApremilast·Deucravacitinib
Bristol-Myers Squibb
Phase 3
729
Ratingen, Cologne, Erlangen, Hamburg, Magdeburg, Minden, Tübingen
2021-07-15
Active, closed
A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)
NCT04657289Neovascular Age-related Macular Degeneration (nAMD)
DrugRanibizumab
Hoffmann-La Roche
Phase 3
451
Bonn, Cologne, Cottbus, Freiburg im Breisgau, Hamburg, Ludwigshafen, München, Münster
2021-07-14
Recruiting
The ABC-HCC Trial: Atezolizumab Plus Bevacizumab vs. Transarterial Chemoembolization (TACE) in Intermediate-stage HepatoCellular Carcinoma
NCT04803994Hepatocellular Carcinoma
DrugsAvastin·Tecentriq·Atezolizumab·Bevacizumab
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Phase 3
434
Aachen, Amberg, Berlin, Bochum, Cologne, Dresden, Düsseldorf, Erlangen
2021-07-06
Active, closed
Long-Term Observational Study on Effectiveness and Safety of Lecigon in Patients With Advanced Parkinson's Disease
NCT05043103Advanced Parkinson Disease
Britannia Pharmaceuticals Ltd.
Observational
312
Bad Segeberg, Beelitz-Heilstätten, Berlin, Cologne, Coppenbrügge, Essen, Freiburg im Breisgau, Göttingen
2021-07-06
Active, closed
Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
NCT04886804Neoplasm Metastasis, Non-Small Cell Lung Cancer
DrugZongertinib
Boehringer Ingelheim
Phase 1
554
Augsburg, Cologne, Dresden, Giessen, Oldenburg
2021-07-02
Active, closed
Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease
NCT04915755Neoplasms, Breast
DrugNiraparib
GlaxoSmithKline
Phase 3
40
Berlin, Cologne, Erlangen, Essen, Mannheim, München, Ulm
2021-06-28
Recruiting
Device Global Registry for the IlluminOss Bone Stabilization System
NCT05206981Traumatic Fracture, Pathological Fracture
IlluminOss Medical, Inc.
Observational
300
Cologne, Minden, Wuppertal
2021-06-11
Active, closed
An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)
NCT04720157Prostatic Neoplasms
DrugsARDT·Illuccix·Lu-PSMA
Novartis Pharmaceuticals
Phase 3
1,140
Würzburg, Cologne, Essen, München, Münster, Rostock
2021-06-09
Active, closed
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus
NCT04877691Systemic Lupus Erythematosus
DrugAnifrolumab
AstraZeneca
Phase 3
367
Berlin, Cologne, Leipzig, Tübingen
2021-06-08
Active, closed
Daratumumab for First Line Treatment of Transplant-ineligible Myeloma Patients Followed by Daratumumab Re-treatment at First Relapse
NCT04656951Multiple Myeloma
DrugsDarzalex·Daratumumab
University of Cologne
Phase 2
67
Cologne
2021-06-01
Active, closed
The SELUTION DeNovo Study
NCT04859985Coronary Artery Disease
M.A. Med Alliance S.A.
Not applicable
3,326
Augsburg, Bad Krozingen, Berlin, Bremen, Bruchsal, Cologne, Dresden, Essen
2021-05-15
Recruiting
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
NCT07218029Pulmonary Arterial Hypertension
DrugSotatercept
Merck Sharp & Dohme LLC
Phase 3
815
Heidelberg, Munich, Regensburg, Giessen, Hanover, Cologne, Dresden, Leipzig
2021-05-12
Active, closed
Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation
NCT04818502Mitral Valve Regurgitation
Abbott Medical Devices
Observational
200
Bad Oeynhausen, Berlin, Bonn, Cologne, Frankfurt, Hamburg, Kiel, Leipzig
2021-05-04
Recruiting
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
NCT04752722Superficial Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ, Non-muscle Invasive Bladder Cancer
DrugPhase 2
enGene, Inc.
Phase 1/2
350
Cologne, Duisburg, Erlangen, Mettmann, Nürtingen, Tübingen
2021-04-22
Recruiting
Tendyne European Experience Registry
NCT04898335Mitral Regurgitation
LMU Klinikum
Observational
400
Bad Oeynhausen, Berlin, Bonn, Cologne, Frankfurt, Hamburg, Leipzig, Mainz
2021-04-15
Active, closed
TRISCEND II Pivotal Trial
NCT04482062Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases
Edwards Lifesciences
Not applicable
864
Bad Oeynhausen, Bonn, Cologne, Dresden, Leipzig, Mainz, München
2021-04-09
Recruiting
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
NCT04655404High Grade Glioma, Diffuse Intrinsic Pontine Glioma
DrugLarotrectinib
Nationwide Children's Hospital
Phase EARLY_PHASE1
15
Heidelberg, Augsburg, Berlin, Cologne, Göttingen
2021-04-08
Recruiting
A Clinical Study to Improve Brain Function and Quality of Life of Patients With Newly Diagnosed Brain Tumors (Gliomas).
NCT05331521Oligodendroglioma
DrugProcarbazine
University Hospital Heidelberg
Phase 3
406
Heidelberg, Berlin, Bochum, Bonn, Chemnitz, Cologne, Düsseldorf, Frankfurt
2021-04-07
Recruiting
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
NCT04728893Hematologic Malignancies, Waldenstroms Macroglobulinaemia, Non-Hodgkins Lymphoma, Chronic Lymphocytic Leukaemia
DrugNemtabrutinib
Merck Sharp & Dohme LLC
Phase 2
490
Ulm, Cologne, Siegen, Dresden
2021-04-05
Active, closed
Retrospective Analysis of the Efficiency of Caplacizumab in the Treatment of aTTP
NCT04985318Acquired Thrombotic Thrombocytopenic Purpura
University of Cologne
Observational
350
Cologne
2021-03-25
Active, closed
Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)
NCT04608318Chronic Lymphoid Leukemia
DrugsIbrutinib·Obinutuzumab·Venetoclax
German CLL Study Group
Phase 3
897
Augsburg, Berlin, Bremen, Cologne, Dortmund, Dresden, Düsseldorf, Eisenach
2021-03-01
Active, closed
Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation
NCT04699188KRAS G12C Mutant Solid Tumors, Carcinoma, Non-Small-Cell Lung, Carcinoma, Colorectal, Cancer of Lung
DrugsTNO155·JDQ443·Tislelizumab
Novartis Pharmaceuticals
Phase 1/2
344
Freiburg im Breisgau, Cologne, Dresden, Essen
2021-02-24
Active, closed
Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation
NCT04685135Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer
DrugsAdagrasib·Taxotere·Docetaxel
Mirati Therapeutics Inc.
Phase 3
453
Bad Berka, Bonn, Cologne, Essen, Gauting, Giessen, Grohansdorf, Halle
2021-02-23
Active, closed
HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer
NCT04619004Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
DrugPatritumab deruxtecan
Daiichi Sankyo
Phase 2
277
Köln, Cologne, Großhansdorf, Dresden
2021-02-02
Recruiting
CIRCULATing Biomarkers for Individualized Surgical Therapy in gastroEsophageal Cancer - Phase 1
NCT04455282Cancer of Esophagus, Esophagogastric Junction Disorder
Heinrich-Heine University, Duesseldorf
Observational
100
Cologne, Münster
2021-02-01
Active, closed
Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair System
NCT04614402Tricuspid Valve Insufficiency
Edwards Lifesciences
Observational
300
Tübingen, Ulm, München, Cologne, Essen, Bad Oeynhausen, Bonn, Leipzig
2021-01-15
Active, closed
A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
NCT04628494Diffuse Large B-cell Lymphoma
DrugEpcoritamab
Genmab
Phase 3
483
Cologne, Essen, Kiel, Würzburg
2021-01-13
Active, closed
A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1
NCT04534205Unresectable Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Cancer, Recurrent Head and Neck Cancer
DrugPembrolizumab
BioNTech SE
Phase 2/3
358
Berlin, Cologne, Hanover, Heidelberg, Iserlohn, Leipzig, Mainz, München
2021-01-07
Active, closed
A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL
NCT04521231B Cell Precursor Acute Lymphoblastic Leukemia
DrugBlinatumomab
Amgen
Phase 1/2
181
Augsburg, Berlin, Cologne, Jena, Leipzig, Tübingen, Ulm
2021-01-04
Active, closed
Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01)
NCT04656652Non-small Cell Lung Cancer
DrugsDatopotamab deruxtecan·Docetaxel
Daiichi Sankyo
Phase 3
605
Berlin, Cologne, Frankfurt am Main, Freiburg im Breisgau, Gauting, Heidelberg, Hemer, Kempten
2020-12-21
Active, closed
A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy
NCT04640623Urinary Bladder Neoplasms
DrugsTAR-200·Cetrelimab
Janssen Research & Development, LLC
Phase 2
220
Cologne, Duisburg, Herne, Markkleeberg, Mettmann, Münster, Nuremberg, Nürtingen
2020-12-18
Active, closed
A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer
NCT04351555Non-Small Cell Lung Cancer
DrugsTagrisso·Osimertinib·Pemetrexed·Cisplatin
AstraZeneca
Phase 3
358
Berlin, Bielefeld, Cologne, Esslingen a.N., Freiburg im Breisgau, Gauting, Georgsmarienhütte, Halle
2020-12-16
Active, closed
Durvalumab and Tremelimumab in Combination With Y-90 SIRT for Intermediate Stage HCC
NCT04522544Hepatocellular Carcinoma Non-resectable, HCC
DrugsTremelimumab·Durvalumab
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Phase 2
55
Bonn, Cologne, Essen, Göttingen, Hanover, Jena, Lübeck, München
2020-12-15
Active, closed
Adjuvant Apalutamide in Subjects With High-risk Localized or Locally Advanced Prostate Cancer After Radical Prostatectomy
NCT04295447Prostatic Neoplasms
DrugApalutamide Tab
Universität Münster
Phase 2
190
Münster, Augsburg, Bergisch Gladbach, Cologne, Duisburg, Düsseldorf, Essen, Frankfurt
2020-12-10
Active, closed
AMEND-CRT: Mechanical Dyssynchrony as Selection Criterion for CRT
NCT04225520Left Ventricular Dyssynchrony, Heart Failure, Cardiomyopathy, Dilated, Cardiac Remodeling, Ventricular
Universitaire Ziekenhuizen KU Leuven
Not applicable
500
Cologne, Rostock, Würzburg
2020-12-10
Active, closed
Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy
NCT04655976Lung Cancer, Non-Small Cell
DrugsCobolimab·Dostarlimab·Docetaxel
GlaxoSmithKline
Phase 2/3
758
Augsburg, Bad Berka, Berlin, Bonn, Cologne, Dresden, Essen, Frankfurt
2020-12-08
Active, closed
A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)
NCT04622319HER2-Positive Primary Breast Cancer, Residual Invasive Breast Cancer
DrugsTrastuzumab emtansine·Trastuzumab deruxtecan
Daiichi Sankyo
Phase 3
1,600
Augsburg, Berlin, Bielefeld, Böblingen, Braunschweig, Bremen, Chemnitz, Cologne
2020-12-04
Recruiting
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
NCT04613596Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer
DrugsAdagrasib·Pembrolizumab
Mirati Therapeutics Inc.
Phase 2/3
626
Immenstadt im Allgäu, Amberg, Augsburg, Bad Homburg, Berlin, Braunschweig, Chemnitz, Cologne
2020-12-02
Active, closed
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
NCT04623541Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome, Treatment-naïve High Risk Chronic Lymphocytic Leukemia
DrugsEpcoritamab·Pirtobrutinib·Lenalidomide·Venetoclax
Genmab
Phase 1/2
194
Cologne, Kiel
2020-11-25
Recruiting
MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO)
NCT04111978Ovarian Neoplasm Epithelial, Fallopian Tube Neoplasms, Peritoneal Neoplasms, High-grade Serous Ovarian Carcinoma (HGSOC)
DrugLetrozole
Swiss GO Trial Group
Phase 3
540
Berlin, Cologne, Deggendorf, Dresden, Düsseldorf, Essen, Esslingen am Neckar, Freiburg im Breisgau
2020-11-05
Recruiting
CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry
NCT04688190Mitral Regurgitation, Mitral Valve Disease, Mitral Annular Calcification
Universitätsklinikum Hamburg-Eppendorf
Observational
1,000
Bad Oeynhausen, Berlin, Bonn, Cologne, Frankfurt, Hamburg, Lübeck, Mainz
2020-11-01
Recruiting
The AFteR Registry - Follow-up Study to Monitor the Efficacy and Safety of the Occlutech AFR in Heart Failure Patients
NCT04405583Heart Failure
Occlutech International AB
Observational
150
Bottrop, Coburg, Cologne, Erfurt, Hamburg, Heide, Jena, Osnabrück
2020-10-28
Active, closed
IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact
NCT04221815Atherosclerosis
Medstar Health Research Institute
Not applicable
3,100
Bad Oeynhausen, Cologne, Bad Segeberg, Dachau, Hamburg, Neuss, Rostock
2020-10-14
Active, closed
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions
NCT04538664Carcinoma, Non-Small-Cell Lung
DrugsAmivantamab·Pemetrexed·Carboplatin
Janssen Research & Development, LLC
Phase 3
308
Bad Berka, Berlin, Cologne, Gauting, Heidelberg, Heilbronn, Moers, Oldenburg
2020-10-13
Active, closed
Sequential Regimen of Bendamustine Followed by Obinutuzumab (GA101), Zanubrutinib (BGB-3111) and Venetoclax (ABT-199) in Patients With Relapsed/Refractory CLL
NCT04515238Chronic Lymphoid Leukemia
DrugsVenclyxto·Bendamustine·Zanubrutinib·Obinutuzumab
German CLL Study Group
Phase 2
42
Augsburg, Cologne, Esslingen am Neckar, Hamm, Homburg, Kiel, Mönchengladbach, Munich
2020-10-01
Recruiting
Characterization of Antibacterial Antibodies in Patients With Cystic Fibrosis
NCT04700358Pulmonary Cystic Fibrosis, Neutralizing Antibodies
University Hospital of Cologne
Observational
75
Cologne
2020-10-01
Active, closed
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT04487080Carcinoma, Non-Small-Cell Lung
DrugsLazertinib·Amivantamab·Osimertinib
Janssen Research & Development, LLC
Phase 3
1,074
Bad Berka, Berlin, Cologne, Essen, Gauting, Halle, Heidelberg, Heilbronn
2020-09-30
Active, closed
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-MutatedProstatic Neoplasms (mCSPC)
NCT04497844Prostatic Neoplasms
DrugsAbiraterone acetate·Prednisone
Janssen Research & Development, LLC
Phase 3
696
Braunschweig, Cologne, Dresden, Duisburg, Hanover, München, Münster, Nürtingen
2020-09-23
Active, closed
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves)
NCT04280718Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
DrugEfgartigimod PH20
argenx
Phase 2
229
Bochum, Cologne, Essen, Göttingen, Kiel, Potsdam
2020-09-18
Active, closed
A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors
NCT04503278Solid Tumor
BioNTech Cell & Gene Therapies GmbH
Phase 1
214
Berlin, Cologne, Erlangen, Hamburg, Hanover, Heidelberg, Mainz, Regensburg
2020-09-16
Active, closed
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)
NCT01817192Non-Small Cell Lung Cancer
Razor Genomics
Not applicable
420
Cologne, Gauting, Georgsmarienhütte, Großhansdorf, Hanover, Lübeck, München, Oldenburg
2020-09-11
Active, closed
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome
NCT04401748Myelodysplastic Syndrome (MDS)
DrugsVenclexta·Azacitidine·Venetoclax
AbbVie
Phase 3
531
Mannheim, Mutlangen, Munich, Hanover, Cologne, Düsseldorf, Leipzig, Berlin
2020-09-10
Active, closed
MINIject Global Long-Term Follow-up Study
NCT04524416Open Angle Glaucoma, Ocular Hypertension
iSTAR Medical
Observational
116
Cologne, Mainz, München
2020-08-05
Active, closed
A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3
NCT04429087Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3
DrugObrixtamig
Boehringer Ingelheim
Phase 1
306
Cologne, Dresden, Würzburg
2020-07-29
Active, closed
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
NCT03935750Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Joint Instability
University of Pittsburgh
Not applicable
1,272
Cologne, Münster
2020-07-28
Active, closed
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)
NCT04245839Lymphoma, Non-Hodgkin
DrugsBreyanzi·Fludarabine·Cyclophosphamide
Celgene
Phase 2
276
Ulm, Regensburg, Cologne, Karlsruhe, Munich
2020-07-14
Active, closed
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
NCT04181827Multiple Myeloma
DrugsCilta-cel·Pomalidomide·Bortezomib·Daratumumab
Janssen Research & Development, LLC
Phase 3
419
Cologne, Dresden, Hamburg, Leipzig, Tübingen, Würzburg
2020-06-12
Active, closed
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
NCT04106219Neuroblastoma
DrugsTopotecan·Cyclophosphamide
Eli Lilly and Company
Phase 1
71
Cologne
2020-06-11
Recruiting
International CIPN Assessment and Validation Study
NCT04633655Chemotherapy-induced Peripheral Neuropathy, Quality of Life
University of Milano Bicocca
Observational
1,000
Cologne
2020-06-08
Active, closed
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases
NCT04307914Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer
UMC Utrecht
Not applicable
216
Cologne
2020-03-10
Recruiting
Leptospirosis Registry - LeptoScope
NCT04288674Leptospirosis
University of Cologne
Observational
200
Cologne
2020-03-04
Recruiting
Hantavirus Registry - HantaReg
NCT04323904Hantavirus Infections, Hemorrhagic Fever With Renal Syndrome, Nephropathia Epidemica, Hantavirus Cardiopulmonary Syndrome
University of Cologne
Observational
200
Cologne
2020-03-04
Rows per page Showing 401–500 of 612
Previous 3 4 5 6 7 Next
Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 30 September 2026. https://priyalifescience.com/clinical-trials-germany/city/cologne?page=5

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,051 studies in total at the last sync on 26 Sep 2026, 19:51 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 612 of those studies with a site in Cologne.

How many clinical trials are recruiting in Cologne?

312 of the 612 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:51 UTC sync. A further 27 have not yet opened recruitment, 261 are active but closed to new participants, and 12 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.