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Trackers› Clinical trials› Aachen
Clinical trial register · Germany

Clinical Trials in Aachen, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5051 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:51 UTC
5051
Studies in scope
all four open statuses
2882
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1584 Hamburg 889 Essen 760 Dresden 707 Heidelberg 627
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Recruitment status
Phase
Lead sponsor
AstraZeneca18 RWTH Aachen University14 Novartis Pharmaceuticals10 Incyte Corporation10 Janssen Research & Development, LLC7
Site location
Berlin1584 Hamburg889 Essen760 Dresden707 Heidelberg627
All 635 locations
Target enrolment
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Trials with a site in Aachen

267 of 5051 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Active, closed
Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple Myeloma
NCT06216158Multiple Myeloma
DrugsIberdomide·Isatuximab·Dexamethasone
University of Heidelberg Medical Center
Phase 3
411
Aachen, Augsburg, Bad Saarow, Berlin, Bielefeld, Bonn, Braunschweig, Chemnitz
2024-04-05
Active, closed
Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)
NCT06291376Immunoglobulin A Nephropathy, IgAN
DrugRavulizumab
Alexion Pharmaceuticals, Inc.
Phase 3
579
Aachen, Berlin, Erlangen, Essen, Greifswald, Hanover, Mainz, München
2024-03-29
Active, closed
A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
NCT06268873Chronic Kidney Disease and Hypertension
DrugBaxdrostat/dapagliflozin
AstraZeneca
Phase 3
2,554
Aachen, Amberg, Bad Oeynhausen, Berlin, Bochum, Dresden, Essen, Falkensee
2024-03-29
Recruiting
A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)
NCT06163430Chronic Myeloid Leukemia, Chronic Phase, Chronic Myeloid Leukemia
Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 1/2
180
Aachen, Berlin, Frankfurt am Main, Hanover, Jena, Mannheim, München
2024-03-26
Active, closed
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy
NCT06333808HIV-1-infection
DrugsBictegravir·Lenacapavir·B/F/TAF
Gilead Sciences
Phase 3
577
Aachen, Berlin, Cologne, Frankfurt, Hamburg, Munich, München
2024-03-25
Active, closed
REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study
NCT06041386Asthma
DrugMepolizumab
GlaxoSmithKline
Phase 4
336
Aachen, Bonn, Darmstadt, Frankfurt, Hohenstein-Ernsttal, Schleswig
2024-03-20
Recruiting
Multicenter, Interdisciplinary National VEXAS Registry With Accompanying Biomaterial Collection
NCT06377462VEXAS Syndrome
Technische Universität Dresden
Observational
500
Aachen, Chemnitz, Dresden, Düsseldorf, Essen, Göttingen, Hamburg, Jena
2024-03-13
Recruiting
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
NCT05939414Oligometastatic Prostate Cancer (OMPC)
DrugsPiflufolastat·Lu-PSMA
Novartis Pharmaceuticals
Phase 3
450
Munich, Cologne, Aachen, Augsburg, Berlin, Essen, Münster, Rostock
2024-03-12
Recruiting
Post-Marketing Surveillance of Vliwazell® Prowound Dressing
NCT07316556Acute and Chronic Wounds
Lohmann & Rauscher
Observational
208
Aachen, Brüggen, Dortmund, Erlangen, Hamburg, Mönchengladbach, Waidhaus, Willich
2024-03-11
Recruiting
Tacrolimus C:D Ratio Measured in Renal Transplant Recipients Treated With Once-daily Prolonged-release Drugs
NCT06268769Immunosuppression
DrugsTacrolimus Pill·Envarsus·Tacrolimus
Edward Geissler
Phase 4
300
Aachen, Berlin, Dresden, Hamburg, Hanover, Jena, Mainz, Münster
2024-03-09
Active, closed
A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
NCT06292013Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a)
DrugLepodisiran
Eli Lilly and Company
Phase 3
17,300
Aachen, Bad Friedrichshall, Bad Homburg, Berlin, Bielefeld, Cologne, Dresden, Essen
2024-03-05
Recruiting
Eye Diseases "Treated" With Interoperable Medical Informatics
NCT06810011Intravitreal Injections
University Hospital Muenster
Observational
2,000
Chemnitz, Aachen, Greifswald, Leipzig, Münster, Tübingen
2024-03-01
Recruiting
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
NCT06165341Alpha1-Antitrypsin Deficiency
DrugFazirsiran
Takeda
Phase 3
50
Aachen, Berlin, Hanover, Tübingen
2024-03-01
Active, closed
Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria
NCT06298955Paroxysmal Nocturnal Hemoglobinuria
DrugOMS906 study drug
Omeros Corporation
Phase 2
25
Aachen, Ulm
2024-02-19
Active, closed
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib
NCT06120140Carcinoma, Non-Small-Cell Lung
DrugsClobetasol·Minocycline·Chlorhexidine·Clindamycin
Janssen Research & Development, LLC
Phase 2
305
Aachen, Essen, Giessen, Heidelberg, Kassel, Kiel
2024-02-16
Active, closed
Early Genetic Identification of Obesity
NCT06239064Obesity, Childhood, Hyperphagia, Retinopathy, Syndactyly
Rolfs Consulting und Verwaltungs-GmbH (RCV)
Observational
1,000
Aachen, Augsburg, Bad Krozingen, Bielefeld, Bonn, Bückeburg, Cologne, Essen
2024-01-24
Active, closed
A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)
NCT06079879Essential Thrombocythemia
DrugsAnagrelide·Bomedemstat·Busulfan·Ruxolitinib
Merck Sharp & Dohme LLC
Phase 3
340
Aachen, Dresden, Halle
2023-12-31
Recruiting
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
NCT06150157Neoplasms
DrugsMomelotinib·Ruxolitinib
Janssen Research & Development, LLC
Phase 1
300
Aachen, Berlin, Essen, Hanover, Heidelberg, Regensburg
2023-12-20
Recruiting
Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)
NCT05512364ER-positive Breast Cancer, HER2-negative Breast Cancer, Stage IIB Breast Cancer, Stage III Breast Cancer
DrugsElacestrant·Tamoxifen·Exemestane·Anastrozole
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3
220
Aachen, Augsburg, Bergisch Gladbach, Bottrop, Bremen, Cologne, Dresden, Hanover
2023-12-15
Active, closed
A Study to Evaluate the Efficacy and Safety of Ropeginterferon Alfa-2b in Essential Thrombocythaemia Patients
NCT06514807Essential Thrombocythaemia
DrugBesremi
AOP Orphan Pharmaceuticals AG
Phase 3
117
Aachen, Halle, Hanover, Mannheim, Minden, Ulm
2023-12-04
Active, closed
A Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-202
NCT06062420Neoplasms, Head and Neck
DrugsRemzistotug·Nelistotug·Belrestotug·Dostarlimab
GlaxoSmithKline
Phase 2
316
Frankfurt am Main, Essen, Aachen, Berlin, Giessen, Hamburg, Regensburg, Ulm
2023-11-14
Active, closed
Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease
NCT06075706Steroid-refractory Acute Graft-versus-host Disease
DrugMC0518
medac GmbH
Phase 2
49
Aachen, Essen, Frankfurt, Freiburg im Breisgau, Giessen, Hanover, Jena, Leipzig
2023-11-13
Active, closed
Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)
NCT06087835Chronic Kidney Disease With High Proteinuria
DrugDapagliflozin
AstraZeneca
Phase 3
1,835
Aachen, Bad Oeynhausen, Berlin, Dresden, Hanover, Mainz, München
2023-11-07
Active, closed
An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
NCT05952557Breast Cancer, Early Breast Cancer
DrugsCamizestrant·Tamoxifen·Exemestane·Anastrozole
AstraZeneca
Phase 3
5,511
Aachen, Berlin, Cologne, Darmstadt, Deggendorf, Dessau, Düsseldorf, Essen
2023-10-05
Active, closed
A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
NCT05936359Myeloproliferative Neoplasms
DrugsINCA033989·Ruxolitinib
Incyte Corporation
Phase 1
160
Aachen, Halle, Ulm
2023-09-25
Active, closed
A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC
NCT05884398Metastatic Castrate-sensitive Prostate Cancer
DrugApalutamide
Janssen Research & Development, LLC
Phase 3
420
Aachen, Augsburg, Cologne, Dresden, Lübeck, München, Nürtingen, Würzburg
2023-08-31
Recruiting
Adjusted High-dose Chemotherapy With Autologous Stem Cell Transplant vs. Conventional Immunochemotherapy in Elderly PCNSL Patients
NCT06830421Primary Central Nervous System Lymphoma
University Hospital Freiburg
Phase 3
340
Freiburg im Breisgau, Stuttgart, Aachen, Augsburg, Berlin, Bielefeld, Bochum, Braunschweig
2023-08-09
Active, closed
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
NCT05797610Primary IgA Nephropathy
Hoffmann-La Roche
Phase 3
459
Leipzig, Aachen, Berlin, Cologne, Hanover, Mainz, Stuttgart, Villingen-Schwenningen
2023-08-08
Active, closed
An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease
NCT05899673Alpha1-Antitrypsin Deficiency
DrugFazirsiran
Takeda
Phase 3
31
Aachen
2023-08-08
Recruiting
Randomized Trial in Adult de Novo Ph Positive ALL With Chemotherapy, Imatinib or Ponatinib, Blinatumomab and SCT
NCT06061094Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
DrugsPonatinib·Imatinib·Blinatumomab
Goethe University
Phase 2
220
Aachen, Aschaffenburg, Augsburg, Bad Saarow, Bayreuth, Berlin, Bielefeld, Bochum
2023-07-14
Recruiting
Diaphragmatic Function as a Biomarker
NCT05903001Dyspnea; Asthmatic, COPD, Fibrosis, Pulmonary Hypertension
RWTH Aachen University
Observational
800
Aachen
2023-07-01
Recruiting
Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study
NCT06016946Friedreich Ataxia
Friedreich's Ataxia Research Alliance
Observational
3,000
Aachen, Bonn, Munich, Tübingen
2023-06-28
Recruiting
Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML
NCT05807932Myelodysplastic Syndromes, Secondary Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia
DrugsMycophenolate Mofetil·Ara-C·Tacrolimus·Venetoclax
Heinrich-Heine University, Duesseldorf
Phase 1/2
38
Aachen, Düsseldorf, Cologne, Frankfurt, Jena, München
2023-06-26
Recruiting
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
NCT05646862Breast Cancer
DrugsBupropion·Omeprazole·Alpelisib·Inavolisib
Hoffmann-La Roche
Phase 3
420
Aachen, Bielefeld, Essen, Freiburg im Breisgau, Georgsmarienhütte, Göttingen, Hamburg, Hanover
2023-06-07
Recruiting
PredIcting sterOid depeNdEnt livEr injuRy With Polyreactive Immunoglobulin G
NCT05810480Autoimmune Hepatitis, Autoimmune Liver Disease
Hannover Medical School
Observational
400
Aachen, Hamburg, Hanover, Heidelberg, Lübeck, Rostock
2023-06-06
Recruiting
Patient-reported, Health Economic and Psychosocial Outcomes in Friedreich Ataxia
NCT05943002Friedreich Ataxia
German Center for Neurodegenerative Diseases (DZNE)
Observational
200
Aachen, Bonn, Münich, Tübingen
2023-06-01
Active, closed
Immunogenicity of COVID-19 Vaccination in Immunocompromised Patients (Auto-COVID-VACC)
NCT05597761COVID-19, Adult, Immunocompromised Patients
Oliver Cornely, MD
Observational
49
Aachen, Cologne, Essen
2023-05-15
Recruiting
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
NCT05716100Focal Onset Seizures
DrugAzetukalner
Xenon Pharmaceuticals Inc.
Phase 3
360
Aachen, Bielefeld, Frankfurt
2023-05-09
Active, closed
IMPACT EU Post-Market Clinical Follow-Up Study
NCT05756751Left Ventricular Dysfunction
Abiomed Inc.
Not applicable
123
Heidelberg, Aachen, Düsseldorf, Essen, Mainz, Halle, Kiel, Berlin
2023-04-27
By invitation
An Open-label Study of XEN1101 in Epilepsy
NCT05718817Focal Epilepsy, Tonic-Clonic Seizures
DrugAzetukalner
Xenon Pharmaceuticals Inc.
Phase 3
880
Aachen, Bielefeld, Frankfurt, Freiburg im Breisgau, Marburg, München, Ulm
2023-04-25
Active, closed
A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) and Placebo Given With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies
NCT05794906Biochemically Recurrent Prostate Cancer
DrugDarolutamide
Bayer
Phase 3
985
Mannheim, Nürtingen, Stuttgart, Würzburg, Frankfurt am Main, Braunschweig, Göttingen, Aachen
2023-04-03
Recruiting
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
NCT05774951Breast Cancer, Early Breast Cancer
DrugsCamizestrant·Tamoxifen·Exemestane·Anastrozole
AstraZeneca
Phase 3
4,300
Aachen, Augsburg, Bayreuth, Berlin, Bonn, Deggendorf, Dessau, Dresden
2023-03-31
Active, closed
Real World Data Collection in Subjects Treated With the FARAPULSE Pulsed Field Ablation System
NCT05501873Atrial Fibrillation
Boston Scientific Corporation
Observational
1,173
Aachen, Dresden, Göttingen, Hamburg, Heidelberg, Karlsruhe, Münster
2023-03-24
Active, closed
Real-world Effectiveness Study of Long-term Treatment With Dupilumab in Participants ≥6 Years With Atopic Dermatitis
NCT06039241Atopic Dermatitis
Sanofi
Observational
572
Aachen, Ahaus, Andernach, Berlin, Braunschweig, Buxtehude, Chemnitz, Cologne
2023-03-07
Recruiting
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
NCT05677971Alpha1-Antitrypsin Deficiency
DrugFazirsiran
Takeda
Phase 3
160
Aachen, Berlin, Hanover, Kiel, Tübingen
2023-03-06
Active, closed
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
NCT05702034Ischemic Stroke; Ischemic Attack, Transient
DrugMilvexian
Janssen Research & Development, LLC
Phase 3
12,523
Aachen, Altenburg, Bad Neustadt an der Saale, Berlin, Dortmund, Dresden, Erlangen, Essen
2023-02-15
Recruiting
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
NCT05667142Primary Generalized Tonic-Clonic Seizures
DrugAzetukalner
Xenon Pharmaceuticals Inc.
Phase 3
160
Aachen, Berlin, Bielefeld, Frankfurt, Freiburg im Breisgau, Marburg, München, Radeberg
2023-02-14
Recruiting
Treatment of Non-resectable Bile Duct Cancer with Radiofrequency Ablation or Photodynamic Therapy
NCT05551299Hilar Cholangiocarcinoma
University of Leipzig
Phase 4
258
Aachen, Augsburg, Berlin, Bonn, Frankfurt, Freiburg im Breisgau, Greifswald, Halle
2023-02-10
By invitation
A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information
NCT05718570Adult Growth Hormone Deficiency
DrugSomapacitan
Novo Nordisk A/S
Observational
400
Aachen, Frankfurt am Main, Halle, Mainz, München, Oldenburg, Würzburg
2023-02-03
Active, closed
GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease
NCT05686551Huntington Disease
Hoffmann-La Roche
Phase 2
301
Aachen, Berlin, Bochum, Bonn, Erlangen, Lübeck, Taufkirchen, Ulm
2023-02-03
Recruiting
Nivolumab in Children and Adults With Nasopharyngeal Carcinoma
NCT06019130Nasopharyngeal Carcinoma, Nasopharyngeal Cancer, Nasopharyngeal Neoplasms, Nasopharynx Cancer
DrugsAvonex·Opdivo·Adrucil·Nivolumab
German Society for Pediatric Oncology and Hematology GPOH gGmbH
Phase 2
57
Aachen, Berlin, Bielefeld, Bonn, Cologne, Cottbus, Dortmund, Dresden
2023-01-10
Active, closed
A Retrospective Analysis of Magnetic Resonance Imaging Data for Breast Cancer Screening in the Open Consortium for Decentralized Medical Artificial Intelligence
NCT05698056Breast Cancer
Technische Universität Dresden
Observational
25,000
Aachen, Dresden
2023-01-01
Active, closed
Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD)
NCT05531526Alzheimer Disease
AriBio Co., Ltd.
Phase 3
1,535
Aachen, Bad Homburg, Berlin, Günzburg, Homburg, Mannheim
2022-12-23
Active, closed
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial
NCT05581303Atherosclerotic Cardiovascular Disease
DrugOlpasiran
Amgen
Phase 3
7,297
Aachen, Bad Krozingen, Bad Oeynhausen, Berlin, Bremen, Cologne, Dresden, Essen
2022-12-14
Recruiting
HRS-AKI Treatment With TIPS in Patients With Cirrhosis
NCT05346393Cirrhosis, Liver, Hepatorenal Syndrome, Acute Kidney Injury, Ascites Hepatic
Jena University Hospital
Not applicable
124
Aachen, Berlin, Dresden, Essen, Freiburg im Breisgau, Halle, Hamburg, Hanover
2022-11-29
Recruiting
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
NCT05623020Multiple Myeloma
DrugsElranatamab·Bortezomib·Daratumumab·Lenalidomide
Pfizer
Phase 3
1,060
Freiburg im Breisgau, Tübingen, Ulm, Mainz, Aachen, Braunschweig, Chemnitz, Hamburg
2022-11-10
Recruiting
PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
NCT04790253Limited Stage Small Cell Lung Cancer, Extensive-stage Small-cell Lung Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Not applicable
600
Aachen
2022-10-27
Active, closed
The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study
NCT05409976Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates
Not applicable
136
Aachen, Arnsberg
2022-10-25
Active, closed
A Study to Learn More About How Well Elinzanetant Works and How Safe it is Compared to Placebo for the Treatment of Hot Flashes Caused by Anti-cancer Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer
NCT05587296Vasomotor Symptoms Caused by Adjuvant Endocrine Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer, Hot Flashes
Bayer
Phase 3
474
Mannheim, Tübingen, Frankfurt am Main, Hanover, Aachen, Bergisch Gladbach, Bonn, Essen
2022-10-14
Recruiting
Diaphragm Atrophy and Dysfunction in Mechanical Ventilation
NCT05211661Diaphragm Issues, Mechanical Ventilation Complication, Respiratory Failure, Intensive Care (ICU) Myopathy
RWTH Aachen University
Observational
20
Aachen
2022-10-10
Recruiting
Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis
NCT04098146Mandibular Reconstruction, Segmental Mandibular Defects
AO Innovation Translation Center
Observational
300
Tübingen, Aachen, Berlin, Hanover, Heidelberg, Leipzig, Munich, Ulm
2022-09-12
Recruiting
Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
NCT05413850Prostate Cancer, Metastatic Castration-resistant Prostate Cancer, mCRPC, Urogenital Neoplasms
Blue Earth Therapeutics Ltd
Phase 1/2
82
Aachen, Augsburg, Essen, Munich
2022-07-20
Active, closed
Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis
NCT05126277Lupus Nephritis
DrugIanalumab
Novartis Pharmaceuticals
Phase 3
452
Aachen, Bochum
2022-07-14
Active, closed
(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis
NCT05186753SSM, Mastocytosis, Indolent, Mastocytosis, Systemic, Mastocytosis
DrugBezuclastinib
Cogent Biosciences, Inc.
Phase 2
237
Aachen, Berlin, Hamburg, Kiel, Mannheim
2022-06-27
Recruiting
CytOSorb TreatMent Of Critically Ill PatientS Registry
NCT05146336Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
CytoSorbents, Inc
Observational
3,000
Aachen, Bad Oeynhausen, Bochum, Essen, Göttingen, Herford, Jena, Kassel
2022-06-22
Recruiting
Effects of Pulmonary Diseases and Their Treatment on Cardiac Function
NCT05042219COPD, Bronchial Asthma, Idiopathic Pulmonary Fibrosis
Ayham Daher
Observational
120
Aachen
2022-06-01
Recruiting
A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
NCT05183646FSGS
DrugRepagermanium
Dimerix Bioscience Pty Ltd
Phase 3
286
Aachen, Cologne, Dresden, Hamburg, Hanover, Lübeck, Mainz, Villingen-Schwenningen
2022-05-30
Recruiting
A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia
NCT05304377Chronic Myeloid Leukemia, Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Cml
DrugELVN-001
Enliven Therapeutics
Phase 1
250
Aachen, Berlin, Frankfurt, Homburg, Jena, Mannheim, Rostock
2022-05-22
Recruiting
Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease
NCT04849806COPD, Sympathetic Nervous System Diseases, Catecholamine; Overproduction
RWTH Aachen University
Observational
135
Aachen
2022-05-10
Active, closed
A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera
NCT05210790Polycythemia Vera
DrugRusfertide
Protagonist Therapeutics, Inc.
Phase 3
293
Aachen, Berlin, Dresden, Greifswald, Hamburg, Koblenz, Mainz
2022-04-01
Active, closed
A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)
NCT05239728Carcinoma, Renal Cell
DrugsBelzutifan·Keytruda·Pembrolizumab
Merck Sharp & Dohme LLC
Phase 3
1,800
Singen, Tübingen, Munich, Aachen, Bonn, Düsseldorf, Essen, Münster
2022-03-15
Active, closed
GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG
NCT05153226Graft Vs Host Disease, Peripheral Blood Stem Cell Transplantation, AML, MDS
DrugCyclophosphamide
DKMS gemeinnützige GmbH
Phase 3
640
Aachen, Augsburg, Chemnitz, Cologne, Dortmund, Dresden, Düsseldorf, Essen
2022-03-02
Active, closed
EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke
NCT05029414Acute Ischemic Stroke
University Hospital, Basel, Switzerland
Not applicable
543
Aachen, Berlin, Bremen, Dresden, Erfurt, Frankfurt, Göttingen, Hamburg
2021-12-09
Recruiting
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
NCT05077904Stereotypical Prolonged Seizures
DrugStaccato alprazolam
UCB Biopharma SRL
Phase 3
350
Aachen, Berlin, Bielefeld, Erlangen, Frankfurt am Main, Kehl-kork, Marburg, München
2021-12-07
Recruiting
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
NCT04910685Indolent Systemic Mastocytosis, Smoldering Systemic Mastocytosis
Blueprint Medicines Corporation
Phase 2/3
534
Aachen, Berlin, Erlangen, Hamburg, Mannheim, Munich
2021-11-30
Recruiting
ITP Registry and Accompanying Biospecimen Collection
NCT05152238Immune Thrombocytopenia
Jena University Hospital
Observational
1,100
Aachen, Altenburg, Aschaffenburg, Bad Homburg, Bad Liebenwerda, Berlin, Biberach, Bochum
2021-11-29
Recruiting
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
NCT04996875Advanced Systemic Mastocytosis (AdvSM), SM With an Associated Hematologic Neoplasm (SM-AHN), Mast Cell Leukemia (MCL), Aggressive Systemic Mastocytosis (ASM)
DrugBezuclastinib
Cogent Biosciences, Inc.
Phase 2
140
Aachen, Freiburg im Breisgau, Lübeck, Mannheim
2021-11-09
Active, closed
A Long-term Extension Study of Ustekinumab in Pediatric Participants
NCT05092269Crohn Disease, Colitis, Ulcerative, Arthritis, Psoriatic
DrugUstekinumab
Janssen Research & Development, LLC
Phase 3
159
Aachen, Berlin
2021-10-18
Active, closed
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP
NCT04971226Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive
DrugsBosutinib·ABL001·Asciminib·Nilotinib
Novartis Pharmaceuticals
Phase 3
405
Mannheim, Frankfurt am Main, Jena, Aachen, Berlin, Lübeck
2021-10-06
Recruiting
Translational Investigation of the Glutamatergic and GABAergic System in Schizophrenia
NCT04655235Schizophrenia
RWTH Aachen University
Observational
600
Aachen, Gangelt
2021-10-01
Active, closed
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
NCT04557462Primary IgA Nephropathy
DrugIptacopan
Novartis Pharmaceuticals
Phase 3
448
Freiburg im Breisgau, Stuttgart, Aachen, Berlin, Essen, Hanover, Kiel, Magdeburg
2021-09-20
Recruiting
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
NCT04973605Relapsed/Refractory Multiple Myeloma
DrugsSonrotoclax·Carfilzomib·Pomalidomide·Daratumumab
BeOne Medicines
Phase 1/2
246
Aachen, Dresden, Hamburg, Würzburg
2021-09-16
Recruiting
Non-invasive Differentiation of Supraventricular Tachyarrhythmia
NCT06061120Supraventricular Arrhythmia, Atrial Fibrillation
RWTH Aachen University
Observational
1,250
Aachen
2021-09-01
Recruiting
European Disease Registry on Retinopathy of Prematurity (ROP)
NCT04939571Retinopathy of Prematurity
University Medicine Greifswald
Observational
3,000
Aachen, Berlin, Bonn, Braunschweig, Chemnitz, Cologne, Cottbus, Düsseldorf
2021-08-06
Active, closed
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
NCT04790370Pulmonary Embolism
Boston Scientific Corporation
Phase 4
544
Aachen, Bielefeld, Bonn, Chemnitz, Freiburg im Breisgau, Immenstädt, Lübeck, Mainz
2021-08-02
Recruiting
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
NCT04817618C3G
DrugIptacopan
Novartis Pharmaceuticals
Phase 3
98
Cologne, Aachen, Erlangen, Essen, Hamburg, Hanover, Heidelberg, Mainz
2021-07-28
Active, closed
Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria
NCT04747613Paroxysmal Nocturnal Hemoglobinuria
DrugIptacopan
Novartis Pharmaceuticals
Phase 3
208
Dresden, Aachen, Essen, Hamburg, Riesa, Ulm
2021-07-27
Recruiting
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
NCT04613921Liver Diseases, Liver Cirrhosis, Acute-On-Chronic Liver Failure, Liver Transplant; Complications
European Foundation for Study of Chronic Liver Failure
Observational
3,000
Regensburg, Kiel, Aachen, Berlin, Frankfurt, Hamburg, Hanover, Heidelberg
2021-07-08
Recruiting
The ABC-HCC Trial: Atezolizumab Plus Bevacizumab vs. Transarterial Chemoembolization (TACE) in Intermediate-stage HepatoCellular Carcinoma
NCT04803994Hepatocellular Carcinoma
DrugsAvastin·Tecentriq·Atezolizumab·Bevacizumab
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Phase 3
434
Aachen, Amberg, Berlin, Bochum, Cologne, Dresden, Düsseldorf, Erlangen
2021-07-06
Recruiting
A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD
NCT04201210HbS Disease, Hemoglobin S Disease, Sickle Cell Anemia, Sickle Cell Disorders
University of Regensburg
Phase 2
212
Aachen, Berlin, Düsseldorf, Frankfurt, Heidelberg, Regensburg, Tübingen, Würzburg
2021-06-30
Recruiting
Postcapillary Blood Gas Analysis in Wedge Position (Wedge-BGA)
NCT04993612Pulmonary Hypertension
Ayham Daher
Observational
100
Aachen
2021-06-25
Active, closed
Non-interventional Study to Collect Real-world Clinical and Patient-reported Outcomes in Ovarian Cancer
NCT04830709Ovarian Cancer
AstraZeneca
Observational
752
Böblingen, Göttingen, Nürtingen, Osnabrück, Rotenburg (Wümme), Aachen, Amberg, Aschaffenburg
2021-06-15
Recruiting
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
NCT04503395Aortic Aneurysm, Abdominal
FCRE (Foundation for Cardiovascular Research and Education)
Not applicable
204
Aachen, Leipzig, München, Münster
2021-05-21
Active, closed
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients
NCT04824092Diffuse Large B-cell Lymphoma
DrugsTafasitamab·Vincristine·Doxorubicin·Prednisone
Incyte Corporation
Phase 3
899
Aachen, Augsburg, Berlin, Bonn, Chemnitz, Cottbus, Göttingen, Halle
2021-05-11
Active, closed
Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function
NCT04763200Left Ventricular Dysfunction, Coronary Artery Disease
Abiomed Inc.
Not applicable
1,252
Erlangen, Munich, Karlsburg, Düsseldorf, Trier, Aachen, Bad Krozingen, Berlin
2021-04-13
Recruiting
DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.
NCT07717437Liver Cancer, Liver Metastases
Maastricht University Medical Center
Observational
350
Aachen, Saarbrücken, Halle
2021-03-16
Active, closed
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
NCT04717414Myeloproliferative Disorders, Myelofibrosis, Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis
DrugLuspatercept
Celgene
Phase 3
313
Aachen, Baden-Warttemberg, Düsseldorf, Halle, Hamburg, Jena, Leipzig, Mannheim
2021-02-25
Active, closed
A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011)
NCT04586231Carcinoma, Renal Cell
DrugsBelzutifan·Cabozantinib·Lenvatinib
Merck Sharp & Dohme LLC
Phase 3
747
Freiburg im Breisgau, Heidelberg, Nuremberg, Frankfurt am Main, Aachen, Homburg/ Saar, Halle, Erfurt
2021-02-25
Active, closed
A Natural History Study to TRACK Brain and Spinal Cord Changes in Individuals with Friedreich Ataxia (TRACK-FA)
NCT04349514Friedreich Ataxia
Monash University
Observational
300
Aachen
2021-02-10
Active, closed
Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia
NCT04579367Hypercholesterolemia, Mixed Dyslipidemia
DrugBempedoic acid
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Observational
5,000
Aachen, Amberg, Aue, Bad Elster, Bad Friedrichshall, Bad Homburg, Bad Krozingen, Bad Segeberg
2021-01-15
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 30 September 2026. https://priyalifescience.com/clinical-trials-germany/city/aachen?page=2

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,051 studies in total at the last sync on 26 Sep 2026, 19:51 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 267 of those studies with a site in Aachen.

How many clinical trials are recruiting in Aachen?

144 of the 267 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:51 UTC sync. A further 7 have not yet opened recruitment, 113 are active but closed to new participants, and 3 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.