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Trackers› Clinical trials› Madrid
Clinical trial register · Spain

Clinical Trials in Madrid, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Spain and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5875 matching records held by the registry are in this view. Synced 11 Oct 2026, 03:18 UTC
5875
Studies in scope
all four open statuses
3096
Recruiting now
open to new participants
1137
Lead sponsors
across recruiting studies
Top sites
Madrid 92 Barcelona 85 Seville 48 Valencia 41 Málaga 28
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca183 Janssen Research & Development, LLC109 Merck Sharp & Dohme LLC106 Novartis Pharmaceuticals100 Hoffmann-La Roche92 Clear sponsor filter
Site location
Madrid92 Barcelona85 Seville48 Valencia41 Málaga28
All 87 locations
Target enrolment
to

Trials with a site in Madrid

92 of 5875 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Spain
Start
Recruiting
Hoffmann-La Roche
Phase 3
380
Marbella, Pamplona, Barcelona, Madrid, Salamanca
2026-06-23
Recruiting
Hoffmann-La Roche
Phase 2/3
650
EL Palmar (EL Palmar), San Cristóbal de La Laguna, Bilbao, Barcelona, Granada, Jaén, Madrid, Málaga
2026-05-21
Recruiting
Hoffmann-La Roche
Phase 3
138
Barcelona, Madrid, Málaga, Seville, Valencia
2026-05-15
Recruiting
Hoffmann-La Roche
Phase 3
360
Barcelona, Madrid, Málaga, Seville, Valencia
2026-04-27
Recruiting
Hoffmann-La Roche
Phase 2
80
L'Hospitalet de Llobregat, Barcelona, Granada, Madrid, Valencia
2026-04-07
Recruiting
Hoffmann-La Roche
Phase 3
1,600
Badalona, A Coruña, Ferrol, Pozuelo de Alarcón, Barcelona, Madrid, Málaga, Seville
2026-03-23
Recruiting
Hoffmann-La Roche
Phase 3
2,000
Santander, A Coruña, Pamplona, Barcelona, Madrid, Seville, Valencia
2026-03-16
Recruiting
Hoffmann-La Roche
Phase 2
100
Barakaldo, Córdoba, Madrid, Valencia
2026-03-11
Recruiting
Hoffmann-La Roche
Phase 2
80
Barcelona, Granada, Madrid, Valencia
2026-02-18
Recruiting
Hoffmann-La Roche
Phase 3
250
Madrid, Seville, Valencia
2025-11-27
Recruiting
Hoffmann-La Roche
Phase 3
900
Elche, Sant Cugat del Vallès, Donostia / San Sebastian, A Coruña, Alcorcón, Pozuelo de Alarcón, Barcelona, Madrid
2025-11-24
Active, closed
Hoffmann-La Roche
Phase 2
193
Las Palmas de Gran Canaria, EL Palmar (EL Palmar), Albacete, Alicante, Barcelona, Madrid, Seville
2025-11-13
Active, closed
Hoffmann-La Roche
Phase 3
1,060
Santander, Barcelona, Madrid, Seville, Valencia
2025-11-12
Recruiting
Hoffmann-La Roche
Phase 3
600
Palma de Mallorca, Santander, Las Palmas de Gran Canaria, Pamplona, Barcelona, Madrid, Málaga, Seville
2025-10-24
Recruiting
Hoffmann-La Roche
Phase 2
12
Madrid, Seville
2025-10-06
Active, closed
Hoffmann-La Roche
Phase 3
1,101
Sant Cugat del Vallès, Terrassa, Donostia / San Sebastian, Lleida, Pozuelo de Alarcón, Barcelona, Córdoba, Madrid
2025-09-17
Recruiting
Hoffmann-La Roche
Phase 2
120
Barcelona, Madrid, Salamanca, Seville, Valencia
2025-09-09
Recruiting
Hoffmann-La Roche
Phase 3
75
Madrid, Seville
2025-06-27
Recruiting
Hoffmann-La Roche
Phase 3
425
Alcorcón, Majadahonda, Madrid, Zaragoza
2025-05-12
Recruiting
Hoffmann-La Roche
Phase 1
405
Pamplona, Barcelona, Madrid
2025-04-30
Active, closed
Hoffmann-La Roche
Observational
44
Madrid, Seville
2025-04-29
Recruiting
Hoffmann-La Roche
Phase 3
450
Elche, L'Hospitalet de Llobregat, Pamplona/iruña, Bilbao, Barcelona, Madrid, Málaga, Seville
2025-04-09
Active, closed
Hoffmann-La Roche
Phase 2
162
Santiago de Compostela, Pamplona, Córdoba, Madrid
2025-04-01
Recruiting
Hoffmann-La Roche
Phase 3
600
Santander, Galdacao, Madrid, Murcia, Valencia, Valladolid
2025-03-17
Active, closed
Hoffmann-La Roche
Phase 4
274
Sant Cugat de Valles, Majadahonda, Burjassot, Valencia(España), Madrid, Seville
2025-03-14
Active, closed
Hoffmann-La Roche
Phase 2
62
L'Hospitalet de Llobregat, Sant Andreu de la Barca, Madrid, Seville, Zaragoza
2024-12-09
Active, closed
Hoffmann-La Roche
Phase 3
338
L'Hospitalet de Llobregat, Seville, Barcelona, Madrid, Málaga, Valencia, Zaragoza
2024-09-23
Active, closed
Hoffmann-La Roche
Phase 1
34
Pamplona, Barcelona, Madrid
2024-09-16
Active, closed
Hoffmann-La Roche
Phase 2
256
Sant Cugat del Vallès, Donostia / San Sebastian, Pozuelo de Alarcón, Salamaca, Barcelona, Córdoba, Madrid, Seville
2024-05-02
Recruiting
Hoffmann-La Roche
Phase 4
320
Madrid, Seville, Valencia
2024-04-02
Active, closed
Hoffmann-La Roche
Phase 1
70
Madrid
2023-12-18
Recruiting
Hoffmann-La Roche
Phase 3
1,100
Santiago de Compostela, Madrid, Valencia
2023-11-22
Recruiting
Hoffmann-La Roche
Phase 1/2
200
Badalona, Madrid, Valencia
2023-11-14
Recruiting
Hoffmann-La Roche
Phase 1/2
60
Esplugues de Llobregat, Madrid, Málaga
2023-09-21
Active, closed
Hoffmann-La Roche
Phase 3
1,130
Santiago de Compostela, Pozuelo de Alarcón, Pamplona, Barcelona, Madrid, Seville, Valencia
2023-09-18
Active, closed
Hoffmann-La Roche
Phase 3
687
Navarra, Pamplona/iruña, Oviedo, Barcelona, Jaén, Madrid, Valencia
2023-09-14
Recruiting
Hoffmann-La Roche
Phase 3
230
A Coruña, Barcelona, Madrid, Málaga, Seville
2023-09-08
Active, closed
Hoffmann-La Roche
Phase 3
459
Lleida, Barcelona, Córdoba, Lugo, Madrid, Seville
2023-08-08
Recruiting
Hoffmann-La Roche
Phase 1/2
320
Badalona, Barcelona, Madrid, Seville, Valencia
2023-06-20
Recruiting
Hoffmann-La Roche
Phase 3
420
L'Hospitalet de Llobregat, Santiago de Compostela, San Cristóbal de La Laguna, Barcelona, Cáceres, Madrid, Málaga, Murcia
2023-06-07
Active, closed
Hoffmann-La Roche
Phase 2
199
Córdoba, Barcelona, Madrid, Seville, Valencia
2023-04-21
Active, closed
Hoffmann-La Roche
Phase 2
204
Barcelona, Madrid
2023-04-13
Active, closed
Hoffmann-La Roche
Phase 2
301
Barakaldo, Badajoz, Barcelona, Burgos, Madrid, Seville, Valencia
2023-02-03
Recruiting
Hoffmann-La Roche
Phase 1/2
65
Barcelona, Madrid
2022-11-16
Active, closed
Hoffmann-La Roche
Phase 1
121
L'Hospitalet de Llobregat, Valencia, Barcelona, Madrid, Salamanca
2022-10-26
Active, closed
Hoffmann-La Roche
Phase 1/2
90
Barcelona, Madrid
2022-10-17
Active, closed
Hoffmann-La Roche
Phase 3
922
Sant Andreu de la Barca, Santiago de Compostela, San Cristóbal de La Laguna, Barcelona, Granada, Huelva, Madrid, Málaga
2022-07-18
Active, closed
Hoffmann-La Roche
Phase 4
136
A Coruña, Barcelona, Madrid, Málaga
2022-06-20
Active, closed
Hoffmann-La Roche
Phase 2/3
97
Esplugues de Llobregas, Madrid, Valencia
2022-06-02
Active, closed
Hoffmann-La Roche
Phase 3
188
Esplugues de Llobregas, Barcelona, Madrid, Seville
2022-05-19
Recruiting
Hoffmann-La Roche
Phase 2
40
Esplugas de Llobregat, Madrid, Valencia
2022-05-12
Active, closed
Hoffmann-La Roche
Phase 3
1,300
L'Hospitalet de Llobregat, Salt, Santiago de Compostela, Majadahonda, Bilbao, Barcelona, Madrid, Málaga
2022-05-03
Active, closed
Hoffmann-La Roche
Phase 2
46
Barcelona, Madrid, Salamanca
2022-03-22
Active, closed
Hoffmann-La Roche
Phase 3
660
A Coruña, Barcelona, Madrid, Málaga, Seville
2021-11-18
Active, closed
Hoffmann-La Roche
Phase 3
478
Guipuzcoa, Madrid, Murcia, Seville, Valencia
2021-10-27
Active, closed
Hoffmann-La Roche
Phase 3
303
Barcelona, Madrid
2021-10-26
Recruiting
Hoffmann-La Roche
Phase 1
542
Donostia / San Sebastian, Majadahonda, Barcelona, Madrid, Valencia, Zaragoza
2021-10-22
Active, closed
Hoffmann-La Roche
Phase 2
176
Barcelona, Madrid, Málaga
2021-10-07
Active, closed
Hoffmann-La Roche
Phase 3
217
A Coruña, Barcelona, Madrid, Málaga
2021-09-30
Active, closed
Hoffmann-La Roche
Phase 1/2
42
Madrid, Seville, Valencia
2021-09-14
Active, closed
Hoffmann-La Roche
Phase 3
451
L'Hospitalet de Llobregat, San Cugat Del Valles, Majadahonda, Pamplona, Oviedo, Barcelona, Córdoba, Madrid
2021-07-14
Active, closed
Hoffmann-La Roche
Phase 3
142
L'Hospitalet de Llobregat, Barcelona, Madrid, Seville
2021-06-25
Recruiting
Hoffmann-La Roche
Phase 1/2
316
Barcelona, Madrid, Valencia
2021-06-22
Active, closed
Hoffmann-La Roche
Phase 3
761
Sabadell, Santander, Córdoba, Donostia / San Sebastian, Barcelona, Madrid, Seville, Valencia
2021-05-03
Active, closed
Hoffmann-La Roche
Phase 3
557
Palma de Mallorca, Santiago de Compostela, Pamplona/iruña, Córdoba, Madrid, Valencia, Zaragoza
2021-04-26
Active, closed
Hoffmann-La Roche
Phase 3
746
L'Hospitalet de Llobregat, Pozuelo de Alarcón, EL Palmar (EL Palmar), Vigo, Barcelona, Madrid, Málaga, Seville
2021-03-17
Active, closed
Hoffmann-La Roche
Phase 1/2
241
Sant Cugat del Vallès, Donostia / San Sebastian, Barcelona, Madrid, Valencia
2021-03-15
Active, closed
Hoffmann-La Roche
Phase 3
270
Barcelona, Madrid, Seville, Valencia
2021-02-23
Active, closed
Hoffmann-La Roche
Phase 3
55
Esplugues de Llobregat, Madrid, Seville
2021-02-04
Active, closed
Hoffmann-La Roche
Phase 2
920
Esplugues de Llobregas, Barcelona, Madrid, Valencia
2021-01-18
Active, closed
Hoffmann-La Roche
Phase 3
769
Pozuelo de Alarcón, Barcelona, Madrid, Murcia
2020-12-03
Active, closed
Hoffmann-La Roche
Phase 3
985
A Coruña, Lleida, Pozuelo de Alarcón, Vigo, Barcelona, Cadiz, Madrid, Málaga
2020-10-26
Active, closed
Hoffmann-La Roche
Phase 3
992
L'Hospitalet de Llobregat, Donostia / San Sebastian, Pozuelo de Alarcón, A Coruña, Barcelona, Madrid, Seville, Valencia
2020-10-09
Active, closed
Hoffmann-La Roche
Phase 3
210
Bilbao, Badalona, Las Palmas de Gran Canaria, Barcelona, Cáceres, Madrid, Salamanca
2020-10-08
Active, closed
Hoffmann-La Roche
Phase 3
190
Badalona, Santiago de Compostela, Asturias, Bilbao, Barcelona, Madrid, Málaga, Salamanca
2020-09-30
Active, closed
Hoffmann-La Roche
Phase 1/2
210
Argentona, Santiago de Compostela, A Gudiña, Las Cabezas de San Juan, Barcelona, Jaén, Madrid, Seville
2020-09-03
Active, closed
Hoffmann-La Roche
Phase 1/2
237
Madrid, Málaga
2020-08-12
Active, closed
Hoffmann-La Roche
Phase 3
271
Barcelona, Madrid
2020-08-10
Active, closed
Hoffmann-La Roche
Phase 2/3
325
Badalona, Pamplona, San Cristóbal de La Laguna, Barcelona, Jaén, Madrid, Seville, Valencia
2020-01-29
Active, closed
Dose Escalation Study of a PD1-LAG3 Bispecific Antibody in Patients With Advanced and/or Metastatic Solid Tumors
NCT04140500Solid Tumors, Metastatic Melanoma, Non-small Cell Lung Cancer, Esophageal Squamous Cell Carcinoma
DrugTobemstomig
Hoffmann-La Roche
Phase 1/2
170
Pamplona, Barcelona, Madrid
2019-11-11
Active, closed
Hoffmann-La Roche
Phase 1/2
498
Barcelona, Madrid, Málaga
2019-08-13
Active, closed
Hoffmann-La Roche
Phase 3
1,013
Pozuelo de Alarcón, El Palmar, Vigo, Barcelona, Madrid, Salamanca, Seville, Valencia
2019-08-12
Active, closed
Hoffmann-La Roche
Phase 3
1,000
Barcelona, Madrid
2019-02-28
Active, closed
Hoffmann-La Roche
Phase 1/2
422
Barcelona, Cáceres, Madrid, Seville
2018-09-25
Active, closed
Hoffmann-La Roche
Phase 3
257
Barcelona, Madrid, Seville, Valencia
2018-08-16
Active, closed
Hoffmann-La Roche
Phase 1/2
211
Barcelona, Madrid, Málaga, Valencia
2018-05-08
Recruiting
Hoffmann-La Roche
Phase 1/2
1,132
Seville, Barcelona, Madrid
2018-03-30
Active, closed
Hoffmann-La Roche
Phase 2/3
1,000
L'Hospitalet de Llobregat, Santiago de Compostela, Pamplona, Alicante, Barcelona, Madrid, Málaga, Seville
2017-09-22
Active, closed
Hoffmann-La Roche
Phase 2
316
Sant Cugat del Vallès, Donostia / San Sebastian, Alcorcón, Pamplona/iruña, Barcelona, Madrid, Seville
2017-06-27
Active, closed
Hoffmann-La Roche
Phase 1/2
940
Badalona, L'Hospitalet de Llobregat, Santander, Barcelona, Madrid
2017-02-21
Active, closed
Hoffmann-La Roche
Phase 1/2
69
Madrid
2016-05-03
Active, closed
Hoffmann-La Roche
Phase 2
534
Fuenlabrada, Barcelona, Madrid, Málaga, Seville
2015-11-19
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Spanish investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 October 2026. https://priyalifescience.com/clinical-trials-spain/city/madrid

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Spain and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,875 studies in total at the last sync on 11 Oct 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 92 of those studies with a site in Madrid that also match the filters currently applied.

How many clinical trials are recruiting in Madrid?

31 of the 92 studies on this page are recruiting new participants as of the 11 Oct 2026, 03:18 UTC sync. A further 0 have not yet opened recruitment, 61 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Madrid), 92 studies
PhaseStudiesRecruitingShare
Phase 3441547.8%
Phase 218619.6%
Phase 1/217618.5%
Phase 1525.4%
Phase 2/3414.3%
Phase 4313.3%
Observational101.1%

Most active sponsors

Lead sponsors with the most studies (Madrid)
Lead sponsorStudiesRecruiting
Hoffmann-La Roche9231
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.