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Trackers› Clinical trials› Leipzig
Clinical trial register · Germany

Clinical Trials in Leipzig, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5051 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:51 UTC
5051
Studies in scope
all four open statuses
2882
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1584 Hamburg 889 Essen 760 Dresden 707 Heidelberg 627
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Recruitment status
Phase
Lead sponsor
AstraZeneca26 Eli Lilly and Company22 University of Leipzig21 Novartis Pharmaceuticals20 Janssen Research & Development, LLC17
Site location
Berlin1584 Hamburg889 Essen760 Dresden707 Heidelberg627
All 635 locations
Target enrolment
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Trials with a site in Leipzig

511 of 5051 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Active, closed
A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment
NCT05455320Multiple Myeloma
DrugsTalquetamab·Pomalidomide·Daratumumab·Dexamethasone
Janssen Research & Development, LLC
Phase 3
864
Berlin, Cologne, Hamburg, Heidelberg, Leipzig, Mainz, Würzburg
2022-10-13
Active, closed
Study Investigating Patient-Reported Outcomes in Lower-risk MDS Patients
NCT05582902MDS, MDS/MPN
University of Leipzig
Observational
60
Berlin, Chemnitz, Dresden, Düsseldorf, Jena, Leipzig, Mainz, Mannheim
2022-10-11
Active, closed
A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies
NCT05453903Leukemia, Myeloid, Acute
DrugsBleximenib·Idarubicin·Daunorubicin·Cytarabine
Janssen Research & Development, LLC
Phase 1
196
Berlin, Dresden, Heidelberg, Leipzig, Ulm
2022-10-04
Recruiting
Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
NCT05327114Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
DrugNipocalimab
Janssen Research & Development, LLC
Phase 2/3
201
Berlin, Bochum, Halle, Hanover, Leipzig, Potsdam
2022-09-23
Active, closed
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
NCT05409066Follicular Lymphoma (FL)
DrugsEpcoritamab·Lenalidomide·Rituximab
Genmab
Phase 3
549
Tübingen, Würzburg, Giessen, Kassel, Göttingen, Bonn, Dresden, Leipzig
2022-09-20
Recruiting
Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis
NCT04098146Mandibular Reconstruction, Segmental Mandibular Defects
AO Innovation Translation Center
Observational
300
Tübingen, Aachen, Berlin, Hanover, Heidelberg, Leipzig, Munich, Ulm
2022-09-12
By invitation
Outcome of Patients With Severe Functional TR According to Medical, Transcatheter or Surgical Treatment
NCT05825898Tricuspid Regurgitation
Ottawa Heart Institute Research Corporation
Observational
3,500
Bad Oeynhausen, Berlin, Bonn, Cologne, Frankfurt, Hamburg, Leipzig, Mainz
2022-09-01
Recruiting
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
NCT05386108Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms
DrugsElacestrant·Abemaciclib
Stemline Therapeutics, Inc.
Phase 1/2
73
Bayreuth, Cologne, Dresden, Düsseldorf, Erlangen, Hanover, Leipzig, Worms
2022-08-31
Active, closed
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)
NCT05500222NASH, Cirrhosis, Liver
DrugResmetirom
Madrigal Pharmaceuticals, Inc.
Phase 3
845
Leipzig, Mainz, Berlin
2022-08-26
Recruiting
A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery
NCT05156983Coagulation Disorder
Takeda
Phase 3
440
Murnau am Staffelsee, Dresden, Leipzig
2022-08-24
Recruiting
Resuscitation Registry in CHD
NCT05373498Cardiac Arrest, Congenital Heart Disease
Leipzig Heart Science gGmbH
Observational
400
Leipzig, Berlin, Bonn
2022-08-18
Recruiting
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
NCT05489705Obstructive Hypertrophic Cardiomyopathy
DrugMavacamten
Bristol-Myers Squibb
Observational
1,700
Aalen, Erlangen, Münster, Dresden, Leipzig, Bernau, Berlin
2022-08-16
Active, closed
An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice
NCT05494606Ulcerative Colitis
AbbVie
Observational
785
Dachau, Darmstadt, Frankfurt am Main, Kassel, Remscheid, Ludwigshafen am Rhein, Saarbrücken, Leipzig
2022-08-15
Recruiting
Perpetual Observational Study - Ventilator Associated Pneumonia
NCT05719259Ventilator Associated Pneumonia
European Clinical Research Alliance for Infectious Diseases (ECRAID)
Observational
20,000
Leipzig
2022-08-03
Recruiting
Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy
NCT05442710Sepsis, Severe
Artcline GmbH
Phase 2
142
Freiburg im Breisgau, Regensburg, Bonn, Cologne, Aue, Leipzig, Halle, Kiel
2022-07-24
Recruiting
A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas
NCT05475925LGLL - Large Granular Lymphocytic Leukemia, Primary Cutaneous Gamma-Delta T-Cell Lymphoma, Primary Cutaneous CD8+ Aggressive Epidermotropic T-Cell Lymphoma, Hepatosplenic T-cell Lymphoma
DrugDibotatug
Dren Bio
Phase 1/2
200
Berlin, Cologne, Leipzig
2022-07-13
Recruiting
International Wilson's Disease Patient Registry (iWilson Registry)
NCT05239858Wilson's Disease
Orphalan
Observational
500
Berlin, Düsseldorf, Hanover, Leipzig
2022-06-29
Active, closed
A Trial to Assess the Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With PLD
NCT05281328Polycystic Liver Disease
DrugCAM2029
Camurus AB
Phase 2/3
71
Hanover, Leipzig, Münster
2022-06-28
Recruiting
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
NCT05429632Adult Acute Myeloid Leukemia
Priothera SAS
Phase 3
366
Freiburg im Breisgau, Halle, Jena, Leipzig, Munich
2022-06-16
Active, closed
A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma
NCT05283720Non-Hodgkin Lymphoma
DrugsGolcadomide·Polatuzumab Vedotin·Epcoritamab·Doxorubicin Hydrochloride
Genmab
Phase 2
264
Ulm, Augsburg, Regensburg, Würzburg, Marburg, Leipzig
2022-06-14
Active, closed
MOTIV BTK Randomized Controlled Trial
NCT05406622Critical Limb Ischemia
REVA Medical, Inc.
Not applicable
292
Leipzig
2022-06-10
Recruiting
A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)
NCT05813678Phenylketonuria (PKU)
DrugPegvaliase
BioMarin Pharmaceutical
Observational
450
Cottbus, Hamburg, Leipzig, Mainz, Münster, Ulm
2022-06-06
Recruiting
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
NCT05076175Colitis, Ulcerative
DrugOzanimod
Bristol-Myers Squibb
Phase 2/3
120
München, Leipzig, Dresden
2022-05-30
Active, closed
An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
NCT05300724Age-Related Macular Degeneration
Genentech, Inc.
Observational
400
Bonn, Freiburg im Breisgau, Göttingen, Hanover, Leipzig, Münster, Tübingen
2022-05-27
Active, closed
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
NCT05269004Multiple Sclerosis
DrugOcrelizumab
Hoffmann-La Roche
Phase 3
1,300
Tübingen, Ulm, Bayreuth, Munich, Westerstede, Düsseldorf, Chemnitz, Leipzig
2022-05-03
Active, closed
Evolut™ EXPAND TAVR II Pivotal Trial
NCT05149755Moderate Aortic Valve Stenosis
Medtronic Cardiovascular
Not applicable
650
Bad Krozingen, Bonn, Dortmund, Leipzig, Mainz, München
2022-04-27
Active, closed
Safety and Effectiveness Evaluation of iCover Covered Stent for the Treatment of the Aorto-iliac Occlusive Disease
NCT05192616Angioplasty, Peripheral Arterial Disease, Iliac Artery Disease, Covered Stent
iVascular S.L.U.
Observational
241
Bad Krozingen, Kaiserslautern, Leipzig, Berlin, Rendsburg
2022-04-27
Recruiting
Intraamniotic Administrations of ER004 to Male Subjects With X-linked Hypohidrotic Ectodermal Dysplasia
NCT04980638X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED)
EspeRare Foundation
Phase 2
20
Erlangen, Leipzig
2022-04-26
Recruiting
Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study
NCT05022485Tibial Fractures, Fracture Infection
Zimmer Biomet
Observational
500
Marburg, Leipzig, Regensburg
2022-04-11
Active, closed
Olorofim Aspergillus Infection Study
NCT05101187Invasive Aspergillosis
DrugAmbisome
F2G Biotech GmbH
Phase 3
225
Leipzig, Berlin, Cologne, Hamburg-Eppendorf
2022-03-31
Active, closed
Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
NCT05317416Multiple Myeloma
DrugsElranatamab·Lenalidomide
Pfizer
Phase 3
854
Würzburg, Mainz, Leipzig, Kiel, Berlin, Chemnitz, Essen, München
2022-03-25
Recruiting
Impact of Microbiome-changing Interventions on Food Decision-making
NCT05353504Overweight and Obesity
Max Planck Institute for Human Cognitive and Brain Sciences
Not applicable
90
Leipzig
2022-03-08
Active, closed
Fragility Fractures of the Pelvis (FFP)
NCT04182776Pelvic Fracture
AO Innovation Translation Center
Observational
420
Hamburg, Leipzig, Mainz
2022-03-01
Recruiting
Study of Progression of Community Acquired Pneumonia in the Hospital in Patients With More Severe Preexisting Diseases and Immunosuppression
NCT05688774Pneumonia, Sepsis, Shock, Septic
Pneumonia Research Network on Genetic Resistance and Susceptibility for the Evolution of Severe Seps
Observational
300
Berlin, Dessau, Hamburg, Leipzig, Marburg, Münster, Rotenburg (Wümme)
2022-02-28
Active, closed
A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis
NCT05070858Generalized Myasthenia Gravis
DrugsCemdisiran·Pozelimab
Regeneron Pharmaceuticals
Phase 3
288
München, Essen, Münster, Leipzig, Berlin, Jena
2021-12-14
Active, closed
Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65).
NCT05116189Ovarian Cancer, Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms
DrugsDocetaxel·Paclitaxel·Bevacizumab·Pembrolizumab
Merck Sharp & Dohme LLC
Phase 3
643
Erlangen, Bonn, Düsseldorf, Krefeld, Saarbrücken, Dresden, Leipzig, Berlin
2021-12-13
Active, closed
A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)
NCT04770779Transfusion-dependent Alpha-Thalassemia, Transfusion-dependent Beta-Thalassemia
DrugMitapivat
Agios Pharmaceuticals, Inc.
Phase 3
258
Berlin, Essen, Leipzig
2021-11-30
Recruiting
A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma
NCT05160584Relapsed/Refractory Multiple Myeloma
Janssen Pharmaceutica N.V., Belgium
Observational
300
Berin, Cologne, Dresden, Hamburg, Hamm, Heidelberg, Karlsruhe, Leipzig
2021-11-18
Active, closed
A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure
NCT04988295Carcinoma, Non-Small-Cell Lung
DrugsLazertinib·Amivantamab·Pemetrexed·Carboplatin
Janssen Research & Development, LLC
Phase 3
776
Berlin, Hamburg, Heidelberg, Heilbronn, Leipzig, Moers, München, Recklinghausen
2021-11-17
Active, closed
Pulmonary Vein Isolation vs SHAM-pulmonary Vein Isolation for Symptomatic Relief in Patients With AF
NCT05119231Atrial Fibrillation
University of Leipzig
Not applicable
262
Coburg, Giessen, Münster, Dresden, Berlin, Leipzig
2021-11-12
Active, closed
Assessment of Effectiveness and Safety of Luspatercept in Patients Suffering From Lower-risk Myelodysplastic Syndrome.
NCT05181592Myelodysplastic Syndromes
DrugsReblozyl·Luspatercept
GWT-TUD GmbH
Phase 3
70
Leipzig, München
2021-10-27
Active, closed
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer
NCT05113251Breast Neoplasms, Breast Cancer, HER2-positive Early Breast Cancer
DrugsHerzuma·Perjeta·Herceptin·Cytoxan
AstraZeneca
Phase 3
927
Augsburg, Berlin, Erlangen, Hamburg, Heidelberg, Kiel, Leipzig, Mönchengladbach
2021-10-25
Active, closed
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular
Not applicable
1,899
Erlangen, Giessen, Homburg, Leipzig, Lübeck
2021-10-20
Active, closed
A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)
NCT05104866Breast Cancer
DrugsVinorelbine·Eribulin·Datopotamab deruxtecan·Capecitabine
AstraZeneca
Phase 3
732
Heidelberg, Homburg, Leipzig, München, Ravensburg
2021-10-18
Active, closed
Study of Lacutamab in Peripheral T-cell Lymphoma
NCT04984837Peripheral T Cell Lymphoma, Relapse/Recurrence
DrugsOxaliplatine·Gemcitabine
The Lymphoma Academic Research Organisation
Phase 2
49
Berlin, Goettigen, Halle, Leipzig, Regensburg
2021-10-05
Recruiting
Safe and Timely Antithrombotic Removal (STAR) Registry
NCT05077124Hemorrhage, Surgical, Hemorrhage Postoperative, Blood Loss, Surgical, Blood Loss, Postoperative
CytoSorbents, Inc
Observational
1,000
Coswig, Erlangen, Essen, Hamburg, Hanover, Heidelberg, Kiel, Leipzig
2021-09-30
Recruiting
Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis
NCT05133843Coronary Artery Stenosis, Transcatheter Aortic Valve Implantation
Helios Health Institute GmbH
Not applicable
50
Leipzig
2021-09-29
Active, closed
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
NCT05050136Primary Biliary Cholangitis, PBC
DrugVolixibat
Mirum Pharmaceuticals, Inc.
Phase 2
333
Chemnitz, Frankfurt, Hanover, Kiel, Leipzig, Magdeburg, Münster, Tübingen
2021-09-22
Active, closed
A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
NCT04965493Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugsRiabni·Ruxience·Truxima·Venclyxto
Loxo Oncology, Inc.
Phase 3
600
Chemnitz, Essen, Kerpener, Koelner Platz 1, Leipzig, Rostock, Würzburg
2021-09-20
Recruiting
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
NCT05006716B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma
DrugTacabrutideg
BeOne Medicines
Phase 1/2
645
Cologne, Dresden, Leipzig, Lübeck, Mainz, München, Ulm
2021-09-13
Active, closed
RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation
NCT05036018Aortic Valve Stenosis
Leipzig Heart Science gGmbH
Not applicable
836
Bad Berka, Bad Oeynhausen, Cologne, Dortmund, Giessen, Leipzig, München, Tübingen
2021-08-30
Active, closed
Predictive Multimodal Signatures Associated With Response to Treatment and Prognosis of Patients With Stage IV Non-small Cell Lung Cancer
NCT04994795Non-small Cell Lung Cancer Metastatic
Sophia Genetics SAS
Observational
4,000
Leipzig
2021-08-21
Active, closed
A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy
NCT04923893Multiple Myeloma
DrugsCilta-cel·Bortezomib·Lenalidomide·Fludarabine
Janssen Research & Development, LLC
Phase 3
743
Berlin, Dresden, Freiburg im Breisgau, Hamburg, Heidelberg, Leipzig, Mainz, München
2021-08-19
Active, closed
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728NASH - Nonalcoholic Steatohepatitis
Inventiva Pharma
Phase 3
1,000
Wiesbaden, Mainz, Homburg, Chemnitz, Dresden, Leipzig, Lübeck, Berlin
2021-08-19
Recruiting
Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients
NCT04844866Diffuse Large B-cell Lymphoma
Miltenyi Biomedicine GmbH
Phase 2
213
Augsburg, Bochum, Cologne, Erlangen, Essen, Hamburg, Heidelberg, Leipzig
2021-08-18
Active, closed
Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma
NCT04674683Unresectable or Metastatic Melanoma, Progressive Brain Metastasis
DrugsChidamide·Nivolumab
HUYABIO International, LLC.
Phase 3
450
Berlin, Cologne, Dresden, Erfurt, Essen, Freiburg im Breisgau, Heidelberg, Leipzig
2021-08-12
Active, closed
OSE2101 Alone or in Combination With Pembrolizumab vs BSC in Patient With Platinum-sensitive Recurrent OC
NCT04713514Platinum-sensitive Ovarian Cancer, Relapsed Ovarian Cancer
DrugsTedopi·Keytruda·Pembrolizumab
ARCAGY/ GINECO GROUP
Phase 2
180
Dresden, Essen, Leipzig, Mainz, Mannheim, Ulm
2021-08-05
Active, closed
Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases
NCT04640142Primary Immune Deficiency
Octapharma
Phase 3
50
Leipzig, Munich
2021-08-04
Active, closed
Statin-Intolerance Registry
NCT04975594Dyslipidemias
University of Leipzig
Observational
1,000
Leipzig
2021-08-01
By invitation
A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus
NCT04976322Systemic Lupus Erythematosus
UCB Biopharma SRL
Phase 3
760
Cologne, Freiburg im Breisgau, Herne, Leipzig, Tübingen, Vogelsang-gommern
2021-07-27
Recruiting
The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial
NCT04284839Bleeding Post Cardiac Surgery, Indication for Anticoagulation
DrugsDOAC·Dabigatran·Edoxaban·Warfarin
Population Health Research Institute
Phase 3
3,500
Leipzig, Jena, Bonn, Essen, Hamburg
2021-07-18
Recruiting
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
NCT04951622Myasthenia Gravis
DrugNipocalimab
Janssen Research & Development, LLC
Phase 3
199
Berlin, Göttingen, Leipzig, Lübeck, Ulm, Wiesbaden
2021-07-15
Active, closed
Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation
NCT04788888Symptomatic Severe Aortic Stenosis
Abbott Medical Devices
Not applicable
434
Bad Nauheim, Berlin, Dortmund, Dresden, Frankfurt, Hamburg, Leipzig, München
2021-07-13
Active, closed
Remote Ischemic Conditioning With Local Ischemic Postconditioning in High-Risk ST-elevation Myocardial Infarction
NCT04844931ST Elevation Myocardial Infarction
Helios Health Institute GmbH
Not applicable
250
Bremen, Dresden, Düsseldorf, Essen, Hamburg, Leipzig, Ludwigshafen, Lübeck
2021-07-05
Active, closed
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral GB2064 in Participants With Myelofibrosis
NCT04679870Myelofibrosis
Galecto Biotech AB
Phase 2
21
Düsseldorf, Heidelberg, Leipzig, München
2021-06-09
Active, closed
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus
NCT04877691Systemic Lupus Erythematosus
DrugAnifrolumab
AstraZeneca
Phase 3
367
Berlin, Cologne, Leipzig, Tübingen
2021-06-08
Active, closed
Proof-of-concept Study for SAR441344 (Frexalimab) in Relapsing Multiple Sclerosis
NCT04879628Multiple Sclerosis
DrugsMRI contrast-enhancing preparations·Frexalimab
Sanofi
Phase 2
129
Leipzig, Münster
2021-06-07
Recruiting
Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
NCT05337631HNSCC, Oral Cavity Cancer, Oropharynx Cancer, Hypopharynx Cancer
University Hospital Freiburg
Observational
1,500
Berlin, Erlangen, Frankfurt, Giessen, Halle, Jena, Kiel, Leipzig
2021-06-01
Recruiting
A Study of BGB-11417 in Participants With Myeloid Malignancies
NCT04771130Acute Myeloid Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasm
DrugsPosaconazole·Sonrotoclax·Azacitidine
BeOne Medicines
Phase 1/2
260
Leipzig, Ulm
2021-05-24
Active, closed
Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)
NCT04704934Gastric Cancer, Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
DrugsRamucirumab·Trastuzumab deruxtecan·Paclitaxel
Daiichi Sankyo
Phase 3
490
Berlin, Dresden Sachsen, Essen, Frankfurt Am Main Hessen, Hamburg, Kln Nordrhein-westfalen, Leipzig
2021-05-21
Recruiting
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
NCT04503395Aortic Aneurysm, Abdominal
FCRE (Foundation for Cardiovascular Research and Education)
Not applicable
204
Aachen, Leipzig, München, Münster
2021-05-21
Active, closed
Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC
NCT04821622Prostate Cancer
DrugsTalazoparib·Enzalutamide
Pfizer
Phase 3
599
Göttingen, Wesel, Jena, Berlin, Duisburg, Frankfurt, Heidelberg, Leipzig
2021-05-12
Recruiting
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
NCT07218029Pulmonary Arterial Hypertension
DrugSotatercept
Merck Sharp & Dohme LLC
Phase 3
815
Heidelberg, Munich, Regensburg, Giessen, Hanover, Cologne, Dresden, Leipzig
2021-05-12
Recruiting
Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System
NCT04838249Transsexualism, Transgenderism, Adiposity, Eating Behavior
University of Leipzig
Observational
80
Leipzig
2021-05-05
Active, closed
Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation
NCT04818502Mitral Valve Regurgitation
Abbott Medical Devices
Observational
200
Bad Oeynhausen, Berlin, Bonn, Cologne, Frankfurt, Hamburg, Kiel, Leipzig
2021-05-04
Active, closed
Observational Clinical Investigation of Arthrosamid in Knee Osteoarthritis
NCT05057559Knee Osteoarthritis
Contura
Observational
201
Leipzig, Mainz
2021-04-21
Active, closed
Study Assessing the Efficacy, Safety and PK of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum
NCT04589650PIK3CA-related Overgrowth Spectrum (PROS)
DrugAlpelisib
Novartis Pharmaceuticals
Phase 2
206
Freiburg im Breisgau, Düsseldorf, Leipzig, Hamburg, Heidelberg
2021-04-19
Recruiting
Tendyne European Experience Registry
NCT04898335Mitral Regurgitation
LMU Klinikum
Observational
400
Bad Oeynhausen, Berlin, Bonn, Cologne, Frankfurt, Hamburg, Leipzig, Mainz
2021-04-15
Active, closed
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
NCT04576156Myelofibrosis
DrugImetelstat sodium
Geron Corporation
Phase 3
327
Mannheim, Tübingen, Dresden, Leipzig, Halle
2021-04-12
Active, closed
TRISCEND II Pivotal Trial
NCT04482062Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases
Edwards Lifesciences
Not applicable
864
Bad Oeynhausen, Bonn, Cologne, Dresden, Leipzig, Mainz, München
2021-04-09
Recruiting
Intermittent Fasting to Improve Insulin Secretion
NCT04607096PreDiabetes, Diabetes type2, Intermittent Fasting, Insulin Secretion
University Hospital Tuebingen
Not applicable
200
Berlin, Dresden, Düsseldorf, Heidelberg, Leipzig, Lübeck, Munich, Tübingen
2021-04-08
Active, closed
SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial
NCT04722250Symptomatic Aortic Stenosis, Aortic Valve Stenosis, Aortic Valve Replacement
Medtronic Cardiovascular
Not applicable
1,103
Bad Oeynhausen, Berlin, Dortmund, Düsseldorf, Kiel, Leipzig, Lübeck, München
2021-04-02
Active, closed
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
NCT04822181Non-alcoholic Steatohepatitis
DrugSemaglutide
Novo Nordisk A/S
Phase 3
1,205
Berlin, Bochum, Bonn, Frankfurt, Hanover, Leipzig, Lübeck, Magdeburg
2021-04-01
Recruiting
CRP Apheresis in STEMI
NCT04939805ST Elevation Myocardial Infarction, C-Reactive Protein, Apheresis, Myocardial Injury
Medical University Innsbruck
Not applicable
202
Lübeck, Leipzig
2021-04-01
Recruiting
The Helios Heart Registry: A Standardized Registry for Patients With Specific Cardiac Diseases
NCT04844944Heart Failure, Coronary Artery Disease, Atrial Fibrillation
Helios Health Institute GmbH
Observational
24,000
Berlin, Erfurt, Gifhorn, Hildesheim, Leipzig, Plauen, Schwerin, Siegburg
2021-03-30
Active, closed
Prospective Long-term Evaluation of the Efficacy and Safety of Calistar S for Transvaginal Pelvic Organ Prolapse Repair
NCT03821142Pelvic Organ Prolapse
Promedon
Not applicable
180
Erfurt, Berlin, Freiburg im Breisgau, Leipzig, Tettnang, Tübingen
2021-03-10
Recruiting
A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)
NCT04710576Chronic Graft-versus-host-disease
DrugAxatilimab
Syndax Pharmaceuticals
Phase 2
296
Dresden, Jena, Leipzig, Mainz, Münster, Regensburg
2021-03-04
Active, closed
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
NCT04717414Myeloproliferative Disorders, Myelofibrosis, Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis
DrugLuspatercept
Celgene
Phase 3
313
Aachen, Baden-Warttemberg, Düsseldorf, Halle, Hamburg, Jena, Leipzig, Mannheim
2021-02-25
Recruiting
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
NCT04545502Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection
Vascutek Ltd.
Observational
2,000
Berlin, Bonn, Freiburg im Breisgau, Hamburg, Leipzig, Mainz, Munich
2021-02-17
Active, closed
Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2
NCT04229979Acute Myeloid Leukemia
DrugsSargramostim·Gm-Csf·Ara-C·Decitabine
Sellas Life Sciences Group
Phase 3
127
Chemnitz, Leipzig, Rostock
2021-02-08
Active, closed
A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma
NCT04657991Melanoma
DrugsBinimetinib·Encorafenib·Keytruda·Pembrolizumab
Pfizer
Phase 3
257
Tübingen, München, Bonn, Minden, Mainz, Dresden, Leipzig, Kiel
2021-01-15
Active, closed
Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair System
NCT04614402Tricuspid Valve Insufficiency
Edwards Lifesciences
Observational
300
Tübingen, Ulm, München, Cologne, Essen, Bad Oeynhausen, Bonn, Leipzig
2021-01-15
Active, closed
A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1
NCT04534205Unresectable Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Cancer, Recurrent Head and Neck Cancer
DrugPembrolizumab
BioNTech SE
Phase 2/3
358
Berlin, Cologne, Hanover, Heidelberg, Iserlohn, Leipzig, Mainz, München
2021-01-07
Active, closed
A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL
NCT04521231B Cell Precursor Acute Lymphoblastic Leukemia
DrugBlinatumomab
Amgen
Phase 1/2
181
Augsburg, Berlin, Cologne, Jena, Leipzig, Tübingen, Ulm
2021-01-04
Active, closed
A Study in Participants With First-Line Nivolumab Plus Ipilimumb Therapy Combined With Two Cycles of Chemotherapy for Metastatic Non-Small Cell Lung Cancer
NCT04794010Carcinoma, Non-Small-Cell Lung
Bristol-Myers Squibb
Observational
825
Leipzig
2020-12-22
Active, closed
A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer
NCT04607421Neoplasms
DrugsEncorafenib·Leucovorin·Irinotecan·Adrucil
Pfizer
Phase 3
841
Munich, Frankfurt am Main, Hanover, Leipzig, Berlin, Charlottenburg, Dresden, Hamburg
2020-12-21
Active, closed
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)
NCT04663308Primary Sclerosing Cholangitis
DrugVolixibat
Mirum Pharmaceuticals, Inc.
Phase 2
182
Hanover, Bonn, Berlin, Erlangen, Kiel, Leipzig, Magdeburg, Tübingen
2020-12-18
Recruiting
HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT)
NCT04447352Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
DrugsCalciumfolinat·Leucovorin·Adrucil·Docetaxel
Krankenhaus Nordwest
Phase 3
200
Aachen, Dresden, Frankfurt, Halle, Leipzig, Ludwigsburg, Lübeck, Magdeburg
2020-12-17
Active, closed
Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia
NCT04490915Congenital Adrenal Hyperplasia
DrugCrinecerfont
Neurocrine Biosciences
Phase 3
182
Dresden, Essen, Frankfurt, Leipzig, Munich
2020-12-16
Active, closed
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)
NCT04548999Multiple Sclerosis
DrugsOcrelizumab·Methylprednisolone
Hoffmann-La Roche
Phase 3
769
Dresden, Greifswald, Hanover, Leipzig, Münster, Tübingen, Ulm, Wiesbaden
2020-12-03
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 30 September 2026. https://priyalifescience.com/clinical-trials-germany/city/leipzig?page=4

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,051 studies in total at the last sync on 26 Sep 2026, 19:51 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 511 of those studies with a site in Leipzig.

How many clinical trials are recruiting in Leipzig?

251 of the 511 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:51 UTC sync. A further 14 have not yet opened recruitment, 239 are active but closed to new participants, and 7 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.