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Trackers› Clinical trials› Alzheimer Disease
Clinical trial register · United States · industry-sponsored

Alzheimer Disease Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9159 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 25 Oct 2026, 03:16 UTC
9159
Studies in scope
industry-sponsored, all four open statuses
4969
Recruiting now
open to new participants
2198
Lead sponsors
across recruiting studies
Top states
Florida 34 California 28 Georgia 20 Arizona 14 Massachusetts 12
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Eli Lilly and Company12 Bristol-Myers Squibb3 Hopeful Aging2 Cognito Therapeutics, Inc.2 Alzheimer's Light LLC2
State
Florida34 California28 Georgia20 Arizona14 Massachusetts12
All 37 states
Target enrolment
to

Alzheimer Disease trials in the USA

48 of 9159 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Not yet open
A Study of LY4560736 in Healthy Participants and Participants With Alzheimer's Disease (AD)
NCT07843459Healthy Volunteers, Alzheimer Disease, Amyloid, Plaque, Amyloid
Eli Lilly and Company
Phase 1
111
California, Florida, Georgia, Michigan
2026-10
Not yet open
Callahan-Young LLC DBA Jigsawdio
Not applicable
80
North Carolina, Texas
2026-10
Recruiting
DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau
NCT07142278Alzheimer Disease, Alzheimer Disease (AD), Preclinical Alzheimer's Disease
Nuravax, Inc.
Phase 1
24
Florida
2026-09-25
Recruiting
Eli Lilly and Company
Phase 1
179
California, Florida, Georgia, Michigan
2026-09-09
Not yet open
2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients
NCT06432166Alzheimer Disease, Mild Cognitive Impairment
MTI Biotech Inc
Phase 1/2
48
Tennessee
2026-09-01
Recruiting
Eli Lilly and Company
Phase 3
550
Arizona, California, Florida, Georgia, Idaho, Illinois, Indiana, Iowa
2026-05-22
Recruiting
Eli Lilly and Company
Phase 1
30
California, Florida, Michigan
2026-05-21
Recruiting
Alpha Cognition, Inc
Phase 4
150
California, Florida, Georgia, Illinois, Indiana, Massachusetts, Michigan, Missouri
2026-05-20
Recruiting
Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
NCT07178210Alzheimer Disease, Lymphatic Obstruction
MMI (Medical Microinstruments, Inc.)
Not applicable
15
California, Florida, New York
2026-04-30
Recruiting
Bristol-Myers Squibb
Phase 3
325
Arizona, California, Florida, Ohio
2026-03-25
Recruiting
Bristol-Myers Squibb
Phase 3
650
Arizona, California, Florida, Georgia, Maryland, Massachusetts, Michigan, Minnesota
2025-12-02
Recruiting
Making Connections Thru Music
NCT06079216Dementia, Alzheimer Disease, Vascular Dementia
Hopeful Aging
Not applicable
196
Massachusetts
2025-12-01
By invitation
Research Study for Patients With Neurological Diseases Which Evaluates the Patient Experience of the MemorEM Device
NCT07222605Alzheimer Disease, Parkinson Disease, Frontotemporal Dementia, Cortico Basal Degeneration
eQ8Health Corporation d/b/a CareONE Concierge
Not applicable
1,000
Georgia
2025-12-01
Recruiting
A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease
NCT07787182Healthy Volunteers, Alzheimer Disease, Amyloid, Plaque, Amyloid
DrugLY4405094
Eli Lilly and Company
Phase 1
68
California, Florida, Georgia, Michigan
2025-10-14
Recruiting
Eli Lilly and Company
Phase 3
3,400
Texas
2025-08-25
Recruiting
Bristol-Myers Squibb
Phase 3
426
Arizona, California, Colorado, Florida, Louisiana, Maryland, Massachusetts, Michigan
2025-07-10
Recruiting
CereMark Pharma, LLC
Phase 3
230
Illinois
2025-07-01
Recruiting
NKGen Biotech, Inc.
Phase 2
30
California
2025-06-30
Recruiting
Celgene
Phase 2
120
Alabama, Arizona, California, Colorado, District of Columbia, Florida, Georgia, Hawaii
2025-06-09
Recruiting
The BRAIN App (Phase 2 SBIR)
NCT06298474Dementia, Alzheimer Disease, Vascular Dementia
Hopeful Aging
Not applicable
120
Massachusetts
2025-05-15
By invitation
Software Validation Study-Cognitive Status Indicator
NCT06809725Alzheimer Disease, Mild Cognitive Impairment, Dementia
Spark Neuro Inc.
Not applicable
600
Florida
2025-03-31
Recruiting
Amydis Inc.
Phase 2
25
Arizona
2025-03-07
Recruiting
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
NCT06847321Alzheimer Disease, Alzheimer Disease Due to P. Gingivalis
Lighthouse Pharmaceuticals, Inc.
Phase 2
300
Arizona, California, Colorado, Florida, Georgia, Kansas, Louisiana, Maryland
2025-02-17
Active, closed
A Spanish-language Caregiver-Enabled Care Program
NCT06631144Dementia, Dementia Alzheimers, Alzheimer Disease, Caregiver
Ceresti Health, Inc.
Not applicable
270
California
2024-12-04
Recruiting
Eli Lilly and Company
Phase 1
128
California, Florida, Georgia, Michigan, New Jersey, North Carolina
2024-10-29
Recruiting
Eli Lilly and Company
Observational
6,250
Alabama
2024-10-07
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
406
Arizona, California, Connecticut, Florida, Georgia, Massachusetts, Michigan, Mississippi
2024-09-26
Recruiting
Intra-Cellular Therapies, Inc.
Phase 2
370
California, Florida, Georgia, New Jersey, North Carolina, Texas, Washington
2024-08-15
Recruiting
Eli Lilly and Company
Phase 1
48
Florida, Georgia, Massachusetts, New Jersey, North Carolina
2024-08-15
Active, closed
Janssen Pharmaceutica N.V., Belgium
Phase 2
55
Arizona, California, Connecticut, Florida, Illinois, Michigan, Mississippi, New Jersey
2024-07-22
Active, closed
Effect of 10 mg Xanamem on Dementia Due to Alzheimer's Disease
NCT06125951Dementia Moderate, Dementia, Mild, Alzheimer Disease
Actinogen Medical
Phase 2/3
247
California, Colorado, Florida, Georgia, New Jersey, New York, Ohio, Oregon
2024-04-12
By invitation
Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)
NCT06245031Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia, Mild
Cognito Therapeutics, Inc.
Not applicable
402
Arizona, California, Colorado, Florida, Georgia, Illinois, Maine, Massachusetts
2024-02-29
Active, closed
Acumen Pharmaceuticals
Phase 2
542
California, Connecticut, District of Columbia, Florida, Georgia, Illinois, Massachusetts, Mississippi
2024-02-29
Active, closed
Alzamend Neuro, Inc.
Phase 1/2
30
Florida
2023-07-05
Active, closed
Lexeo Therapeutics
Phase 1
10
Florida, North Carolina
2023-05-08
Recruiting
Herrick Medical LLC
Not applicable
40
New Jersey
2023-05-01
Active, closed
Oligomerix, Inc
Phase 1
76
California
2023-01-20
Active, closed
AriBio Co., Ltd.
Phase 3
1,535
Arizona, California, Colorado, Florida, Georgia, Illinois, Louisiana, Massachusetts
2022-12-23
Recruiting
[18F]PI-2620 Phase 3 Histopathological Study
NCT05641688Alzheimer Disease
Lantheus Biosciences Ltd.
Phase 3
200
Arizona, California, Florida, Massachusetts, Nebraska, New Hampshire, New York, North Carolina
2022-12-01
Active, closed
Clinical Trial on Agitation in Alzheimer's Dementia
NCT05543681Alzheimer Disease, Agitation,Psychomotor, Care Giving Burden, NPS
IGC Pharma, LLC
Phase 2
164
Florida, Louisiana, Maryland, Missouri, New York, Oklahoma, Rhode Island, Texas
2022-10-11
Active, closed
Eli Lilly and Company
Phase 3
2,996
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Idaho
2021-08-27
Recruiting
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
NCT04800588Alzheimer Disease, Cognitive Decline, Aging
Neurobehavioral Systems, Inc.
Not applicable
2,000
California
2021-05-05
Active, closed
Eli Lilly and Company
Phase 3
1,736
Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida, Georgia
2020-06-19
Recruiting
Longitudinal Cognitive Assessment by BoCA
NCT04114994Alzheimer Disease, Mild Cognitive Impairment, Vascular Dementia, Frontotemporal Dementia
Alzheimer's Light LLC
Observational
10,000
Florida
2019-10-01
Recruiting
InSightec
Not applicable
50
Florida, New York, Ohio, Texas, West Virginia
2018-09-28
Active, closed
Multi-Center Study of Sensory Stimulation to Improve Brain Function
NCT03556280Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia Alzheimers
Cognito Therapeutics, Inc.
Not applicable
60
Florida, Massachusetts, New Jersey
2018-04-24
Recruiting
Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
NCT03657745Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognition Disorders in Old Age
Alzheimer's Light LLC
Observational
2,000
Florida
2018-01-01
Active, closed
Eli Lilly and Company
Observational
1,400
California, Colorado, Connecticut, Florida, Georgia, Indiana, Kansas, Kentucky
2016-10-29
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 25 October 2026. https://priyalifescience.com/clinical-trials-usa/condition/alzheimer-disease

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,159 studies in total at the last sync on 25 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 48 of those studies listing the condition Alzheimer Disease.

How many Alzheimer Disease trials are recruiting in the US?

29 of the 48 studies on this page are recruiting new participants as of the 25 Oct 2026, 03:16 UTC sync. A further 3 have not yet opened recruitment, 13 are active but closed to new participants, and 3 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Alzheimer Disease), 48 studies
PhaseStudiesRecruitingShare
Not applicable12625%
Phase 311822.9%
Phase 19618.8%
Phase 28516.7%
Observational438.3%
Phase 1/2204.2%
Phase 2/3102.1%
Phase 4112.1%

Most active sponsors

Lead sponsors with the most studies (Alzheimer Disease)
Lead sponsorStudiesRecruiting
Eli Lilly and Company128
Bristol-Myers Squibb33
Alzheimer's Light LLC22
Cognito Therapeutics, Inc.20
Hopeful Aging22
Actinogen Medical10
Acumen Pharmaceuticals10
Alpha Cognition, Inc11
Alzamend Neuro, Inc.10
Amydis Inc.11

Top states

Top states (Alzheimer Disease), by number of studies with a site there
StateStudies
Florida34
California28
Georgia20
Arizona14
Massachusetts12
Michigan10
Colorado9
Illinois7
New Jersey7
Connecticut6
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.