California Cognitive Assessment Battery: The California Cognitive Assessment Battery (CCAB) is a collection of computerized cognitive tests that will be telemedically administered to participants in their homes using a tablet computer and accessories provided by the research team. Testing may also occur in research laboratories. Previous versions of CCAB tests have been described in 16 manuscripts which describe (a) the psychometric characteristics of normative data collected in large participant populations (300 to 2,300 subjects for different tests) and (b) the sensitivity of CCAB tests for detecting performance abnormalities in patients with traumatic brain injury (TBI) and in control participants simulating the cognitive deficits that follow mild TBI.
Study summary
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed computerized cognitive tests. These tests are designed to permit the early detection of individuals at risk of age-related cognitive decline.
Eligibility
Sex
ALL
Min age
18 Years
Max age
89 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Must be able to use computer mouse and touch screen
* Must speak English as a primary language
* Must speak Spanish as a primary language (for Latino participants completing our Spanish translation)
Exclusion Criteria:
* History of psychiatric disorder
* History of stroke or transient ischemic attack
* History of substance abuse
* History of medical or sensory disorders that are incompatible with effective testing
* History of traumatic brain injury with hospitalization and extended loss of consciousness
* History of epilepsy
* History of depression or anxiety
Primary outcome measure(s)
Longitudinal normative data collection from healthy participants — Longitudinal testing at six-month intervals Multiple behavioral outcome measures will be obtained from each cognitive test including measures of response time (in milliseconds) and accuracy (in percent correct). Recordings of subject's verbal responses will also be analyzed phonologically and automatically transcribed to permit the lexical, syntactic, and semantic analysis of speech output. Questionnaire data will be used to identify factors that may influence performance on the cognitive tests. The primary outcome measures are the scores obtained during enrollment testing that predict a decline in longitudinal performance.
Trial sites (1)
Facility
City
Region
Status
Neurobehavioral Systems, Inc.
Berkeley
California
Recruiting
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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