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Trackers› Clinical trials› Leipzig
Clinical trial register · Germany

Clinical Trials in Leipzig, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5051 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:51 UTC
5051
Studies in scope
all four open statuses
2882
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1584 Hamburg 889 Essen 760 Dresden 707 Heidelberg 627
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca26 Eli Lilly and Company22 University of Leipzig21 Novartis Pharmaceuticals20 Janssen Research & Development, LLC17
Site location
Berlin1584 Hamburg889 Essen760 Dresden707 Heidelberg627
All 635 locations
Target enrolment
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Trials with a site in Leipzig

511 of 5051 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Active, closed
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)
NCT04544436Multiple Sclerosis
DrugsOcrelizumab·Methylprednisolone
Hoffmann-La Roche
Phase 3
864
Berlin, Bochum, Dresden, Kiel, Leipzig, Ulm, Wiesbaden
2020-11-26
Active, closed
Evaluation of Safety and Performance of the Omega™ LAA (Left Atrial Appendage) Occluder and Omega™ Delivery System in Patients With Non-Valvular Atrial Fibrillation and High Bleeding Risk
NCT04829929Non-Valvular Atrial Fibrillation
Eclipse Medical Ltd.
Not applicable
200
Frankfurt, Berlin, Leipzig
2020-11-17
Recruiting
LANDMARK Trial: a Randomised Controlled Trial of Myval THV
NCT04275726Aortic Valve Stenosis
Meril Life Sciences Pvt. Ltd.
Not applicable
988
Bad Nauheim, Leipzig, Bad Krozingen, Braunschweig, Dresden, Hamburg, Regensburg
2020-11-04
Recruiting
Abbott Vascular Medical Device Registry
NCT04573660Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
Abbott Medical Devices
Observational
3,784
Frankfurt am Main, Mainz, Leipzig, Bad Bevensen, Kiel
2020-10-25
Recruiting
Comparison of Vessel-FFR Versus FFR in Intermediate Coronary Stenoses
NCT03497637Coronary Artery Disease, Coronary Artery Stenoses
Helios Health Institute GmbH
Not applicable
1,054
Dresden, Erlangen, Essen, Giessen, Leipzig, Ludwigshafen, Neuss
2020-10-23
Active, closed
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
NCT04590963Squamous Cell Carcinoma of the Head and Neck
DrugsMonalizumab·Cetuximab
AstraZeneca
Phase 3
370
Berlin, Essen, Freiburg im Breisgau, Hanover, Leipzig, Ulm, Würzburg
2020-10-02
Active, closed
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
NCT04526665Primary Biliary Cirrhosis
DrugElafibranor
Ipsen
Phase 3
161
Berlin, Frankfurt, Hanover, Kiel, Leipzig, Mainz
2020-09-24
Active, closed
A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
NCT04557098Hematological Malignancies
DrugTeclistamab
Janssen Research & Development, LLC
Phase 2
194
Heidelberg, Leipzig, Tübingen, Würzburg
2020-09-17
Active, closed
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome
NCT04401748Myelodysplastic Syndrome (MDS)
DrugsVenclexta·Azacitidine·Venetoclax
AbbVie
Phase 3
531
Mannheim, Mutlangen, Munich, Hanover, Cologne, Düsseldorf, Leipzig, Berlin
2020-09-10
Active, closed
BGP+ Stent as Bridging Stent in BEVAR
NCT03982940Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture
Marc Bosiers, MD
Not applicable
118
Heidelberg, Kiel, Aachen, Hamburg, Leipzig, Munich, Münster, Nuremberg
2020-09-09
Active, closed
Diagnosing Heart Failure With Preserved Ejection Fraction in Patients With Unexplained Dyspnea (Diagnose-HFpEF)
NCT04688905Dyspnea
University of Leipzig
Observational
30
Leipzig
2020-09-09
Active, closed
Prospective and Non-randomized Registry of CardioCel 3D
NCT04175327Intracardiac and Septal Defects, Valve and Anulus Repair, Great Vessel Reconstruction, Peripheral Vessel Reconstruction
LeMaitre Vascular
Observational
200
Leipzig
2020-08-28
Active, closed
An Observational Real-world Study Evaluating Severe Tricuspid Regurgitation Patients Treated With the Abbott TriClip™ Device (bRIGHT)
NCT04483089Tricuspid Valve Regurgitation
Abbott Medical Devices
Observational
511
Bonn, Mainz, Leipzig, Bad Berka, Bad Oeynhausen, Bad Rothenfelde, Berlin, Dortmund
2020-08-27
Active, closed
Combination of Ranibizumab and Targeted Laser Photocoagulation
NCT04444492Central Retinal Vein Occlusion With Macular Edema
DrugsLucentis·Ranibizumab
University of Giessen
Phase 3
88
Freiburg im Breisgau, Giessen, Hanover, Leipzig, Ludwigshafen, Marburg, München, Münster
2020-08-25
Recruiting
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)
NCT04419649Myelodysplastic Syndromes, Cytopenia
DrugElritercept
Takeda
Phase 2
160
Bayreuth, Berlin, Bonn, Düsseldorf, Esslingen am Neckar, Halle, Leipzig, Mainz
2020-08-19
Active, closed
Phase III Study of MR-Guided Focused Ultrasound Surgery for the Treatment of Uterine Fibroids Compared to Myomectomy
NCT03948789Uterine Fibroids
Krankenhaus Nordwest
Phase 3
127
Frankfurt am Main, Göttingen, Leipzig, Stuttgart
2020-07-15
Active, closed
Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study
NCT04371055Ischemic Stroke, Atrial Fibrillation
University of Leipzig
Not applicable
5,227
München, Nuremberg, Bremen, Leipzig, Berlin, Altenburg, Aschaffenburg, Augsburg
2020-07-07
Recruiting
Safety and Early Signs of Efficacy of IL12-L19L19.
NCT04471987Advanced Solid Tumor, Metastatic Solid Tumor
Philogen S.p.A.
Phase 1
80
Hamburg, Heidelberg, Leipzig, Tübingen
2020-07-01
Active, closed
Innoventric Trillium™ Stent Graft First-in-Human (FIH) Study
NCT04289870Tricuspid Regurgitation
Innoventric LTD
Not applicable
20
Bad Oeynhausen, Berlin, Leipzig
2020-06-24
Active, closed
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease
NCT04232553Crohn's Disease
DrugMirikizumab
Eli Lilly and Company
Phase 3
996
Pforzheim, Würzburg, Frankfurt am Main, Lauterbach, Hanover, Bottrop, Wipperfürth, Leipzig
2020-06-22
Active, closed
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
NCT04181827Multiple Myeloma
DrugsCilta-cel·Pomalidomide·Bortezomib·Daratumumab
Janssen Research & Development, LLC
Phase 3
419
Cologne, Dresden, Hamburg, Leipzig, Tübingen, Würzburg
2020-06-12
Active, closed
Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System
NCT04201132Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis
Contego Medical, Inc.
Not applicable
305
Bad Krozingen, Berlin, Frankfurt, Hamburg, Leipzig, Radebeul
2020-06-12
Active, closed
Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat in Participants With RRMM
NCT07084896Multiple Myeloma
DrugsNirogacestat·Belantamab mafodotin
GlaxoSmithKline
Phase 1/2
106
Frankfurt, Kiel, Leipzig
2020-06-08
Recruiting
Acotec DCB Post Market Clinical Follow-up
NCT04393389Peripheral Artery Disease
Acotec Scientific Co., Ltd
Observational
3,000
Halle, Eilenburg, Leipzig, Radebeul, Riesa, Sonneberg, Torgau
2020-06-04
Active, closed
Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
NCT04379596Gastric Cancer
DrugsVolrustomig·Rilvegostomig·Trastuzumab deruxtecan·Fluorouracil
AstraZeneca
Phase 2
452
Frankfurt, Hamburg, Leipzig, Mannheim, München
2020-06-03
Active, closed
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer
NCT04269200Endometrial Neoplasms
DrugsOlaparib·Durvalumab·Paclitaxel·Carboplatin
AstraZeneca
Phase 3
805
Bonn, Chemnitz, Dresden, Leipzig
2020-05-05
Active, closed
A Post Market Clinical Follow-up Study With the aneXys Cup
NCT03274830Arthroplasty, Replacement, Hip
Mathys Ltd Bettlach
Observational
102
Berlin, Leipzig
2020-03-05
Recruiting
The Leipzig TAVI Registry
NCT05015452Aortic Valve Stenosis
Helios Health Institute GmbH
Observational
20,000
Leipzig
2020-03-01
Active, closed
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension
NCT04175600Hypertension, Pulmonary
DrugSelexipag
Actelion
Phase 3
138
Freiburg im Breisgau, Heidelberg, Leipzig, München
2020-01-16
Active, closed
Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group
NCT04230759Anal Cancer, Anal Carcinoma, Anal Cancer Stage III, Anal Cancer Stage II
DrugDurvalumab
Goethe University
Phase 2
180
Darmstadt, Dresden, Freiburg im Breisgau, Essen, Kiel, Leipzig, Magdeburg, Mainz
2020-01-07
Active, closed
Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia
NCT04150887Leukemia, Myeloid, Acute
DrugsCusatuzumab·Venclexta·Azacitidine·Venetoclax
OncoVerity, Inc.
Phase 1
61
Hamburg, Leipzig, München
2019-12-23
Recruiting
Medtronic Cardiac Surgery PMCF Registry
NCT04073420Valve Disease, Heart
Medtronic Cardiac Surgery
Observational
2,700
Bad Rothenfelde, Dresden, Düsseldorf, Hamburg, Leipzig, München
2019-12-02
Recruiting
Quality of Life in Women With X-linked Adrenoleukodystrophy
NCT04675749X-linked Adrenoleukodystrophy
Leipzig University Medical Center
Observational
200
Leipzig
2019-12-01
Active, closed
HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
NCT04153149Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
DrugVutrisiran
Alnylam Pharmaceuticals
Phase 3
655
Frankfurt am Main, Leipzig, Essen, Göttingen, Heidelberg, Münster, Würzburg
2019-11-26
Active, closed
Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia
NCT04232241Acute Myeloid Leukemia in Remission, Acute Lymphoblastic Leukemia in Remission, Myelodysplastic Syndromes
Universitätsklinikum Hamburg-Eppendorf
Phase 2
167
Düsseldorf, Essen, Frankfurt, Freiburg im Breisgau, Hamburg, Hanover, Leipzig, Münster
2019-11-14
Active, closed
IMGN632 as Monotherapy or With Venetoclax and/or Azacitidine for Participants With CD123-Positive Acute Myeloid Leukemia
NCT04086264Acute Myeloid Leukemia
DrugsIMGN632·Azacitidine·Venetoclax
AbbVie
Phase 1/2
218
Ulm, Münster, Leipzig
2019-11-06
Recruiting
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
NCT04065399Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Mixed Lineage Acute Leukemia, Mixed Phenotype Acute Leukemia
DrugsCobicistat·Revumenib
Syndax Pharmaceuticals
Phase 1/2
447
Ulm, Essen, Greifswald, Gutenberg, Hamburg, Leipzig, Nuremberg
2019-11-05
Active, closed
An All-Comers Observational Study of the MicroStent™ Peripheral Vascular Stent System in Subjects With Peripheral Arterial Disease
NCT04110327Peripheral Arterial Disease, Critical Lower Limb Ischemia
Micro Medical Solution, Inc.
Observational
300
Arnsberg, Bad Krozingen, Leipzig
2019-10-31
Recruiting
Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)
NCT04075084Tachycardia, Atrial Fibrillation, Syncope, Bradycardia
Biotronik SE & Co. KG
Observational
1,400
Ahaus, Bad Nauheim, Bad Neustadt an der Saale, Dresden, Erfurt, Herford, Leipzig, Mitte
2019-10-28
Active, closed
SJM Masters HP 15mm Rotatable Mechanical Heart Valve as Aortic Valve Replacement Therapy
NCT03924661Aortic Valve Disease
Abbott Medical Devices
Observational
20
Stuttgart, München, Leipzig, Hanover
2019-10-24
Recruiting
Alloplastic Total Temporomandibular Joint (TMJ) Replacement Registry
NCT03991728Temporomandibular Joint Disorders
AO Innovation Translation Center
Observational
200
Hanover, Leipzig, Mainz, Munich
2019-10-15
Active, closed
Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
NCT04126200Multiple Myeloma
DrugsFeladilimab·Nirogacestat·Belantamab mafodotin·Isatuximab
GlaxoSmithKline
Phase 1/2
208
Frankfurt, Hamburg, Kiel, Leipzig
2019-10-07
By invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
NCT03683186PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension
United Therapeutics
Phase 3
1,000
Heidelberg, Greifswald, Mainz, Homburg, Leipzig, Donaueschingen, Dresden, Hamburg
2019-09-23
Active, closed
Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patients
NCT04121455Glioblastoma
DrugsTemozolomide·Keytruda·Bevacizumab·Pembrolizumab
TME Pharma AG
Phase 1/2
117
Bonn, Essen, Leipzig, Mannheim, Münster, Tübingen
2019-09-12
Recruiting
Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections
NCT04832607AdV Infection, EBV Infection, CMV Infection, Stem Cell Transplant Complications
Tobias Feuchtinger
Phase 3
149
Berlin, Dresden, Düsseldorf, Essen, Freiburg im Breisgau, Hanover, Leipzig, Munich
2019-08-27
Active, closed
TRILUMINATE Pivotal Trial
NCT03904147Tricuspid Regurgitation
Abbott Medical Devices
Not applicable
572
München, Bonn, Mainz, Leipzig
2019-08-21
Recruiting
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
NCT04064060Myelodysplastic Syndromes (MDS), Beta-thalassemia, Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
DrugLuspatercept
Celgene
Phase 3
665
Berlin, Dresden, Düsseldorf, Halle, Hamburg, Hanover, Leipzig, Mainz
2019-08-12
Active, closed
Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine
NCT03836040Migraine
DrugAimovig
Amgen
Phase 3
457
Berlin, Essen, Greifswald, Kiel, Leipzig
2019-07-19
Active, closed
A Study of the Temporary Spur Stent for the Treatment of Narrowing and Blockages in the Arteries Below the Knee
NCT03807531Peripheral Arterial Disease
ReFlow Medical, Inc.
Not applicable
100
Arnsberg, Bad Krozingen, Leipzig, Rosenheim
2019-07-11
Active, closed
IMPEDE and IMPEDE-FX Embolization Plug Registry
NCT04044443Peripheral Vascular Embolization
Shape Memory Medical, Inc.
Observational
108
Dresden, Heidelberg, Kiel, Leipzig, München, Nuremberg, Stuttgart, Würzburg
2019-07-09
Active, closed
Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL
NCT03960840Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Diffuse Large B-cell Lymphoma, Acute Lymphoblastic Leukemia
DrugIbrutinib
Novartis Pharmaceuticals
Phase 1/2
217
Frankfurt am Main, Leipzig
2019-06-26
Recruiting
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress
NCT03968393Stroke, Atrial Fibrillation
DrugsNon-Vitamin K Anticoagulant·NOAC·Dabigatran·Edoxaban
Population Health Research Institute
Phase 4
2,270
Leipzig
2019-06-14
Recruiting
Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk
NCT04029363Mitral Regurgitation
HighLife SAS
Not applicable
120
Bad Krozingen, Bonn, Dresden, Hamburg, Heidelberg, Leipzig, Munich, Rostock
2019-05-28
Active, closed
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
NCT03253263Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Intraventricular Hemorrhage, Retinopathy of Prematurity (ROP)
OHB Neonatology Ltd.
Phase 2
295
Leipzig, Nuremberg
2019-05-09
Active, closed
Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment
NCT03847428Hepatocellular Carcinoma
DrugsAvastin·Durvalumab·Bevacizumab
AstraZeneca
Phase 3
908
Berlin, Bonn, Chemnitz, Cologne, Freiburg im Breisgau, Heidelberg, Leipzig, Lübeck
2019-04-29
Active, closed
Inspiris Resilia Durability Registry
NCT03666741Aortic Valve Stenosis
Institut für Pharmakologie und Präventive Medizin
Observational
400
Freiburg im Breisgau, Leipzig
2019-04-26
Active, closed
Automatic PredICtion of Edema After Stroke
NCT04057690Stroke, Acute, Brain Edema
University Hospital Tuebingen
Observational
1,687
Berlin, Bonn, Bremen, Düsseldorf, Hamburg, Hanover, Heidelberg, Leipzig
2019-04-01
Active, closed
A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis
NCT03900429NASH - Nonalcoholic Steatohepatitis
DrugResmetirom
Madrigal Pharmaceuticals, Inc.
Phase 3
1,759
Berlin, Frankfurt am Main, Homburg, Leipzig, Mainz, Würzburg
2019-03-28
Recruiting
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia
NCT03850574Leukemia, Myeloid, Acute, Refractory AML, Relapsed Adult AML, Myelodysplastic Syndrome With Excess Blasts-2
DrugsAzacitidine·Venetoclax
Aptose Biosciences Inc.
Phase 1/2
240
Leipzig, Berlin
2019-03-11
Active, closed
Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX
NCT03754790Hemophilia
DrugFitusiran
Genzyme, a Sanofi Company
Phase 3
281
Berlin, Leipzig
2019-01-09
Active, closed
BEST SFA Pilot Study - Best Endovascular STrategy for Complex Lesions of the Superficial Femoral Artery
NCT03776799Peripheral Arterial Disease
University of Leipzig
Not applicable
120
Leipzig
2019-01-01
Active, closed
Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS
NCT03650114Relapsing Multiple Sclerosis
Drugs13-valent pneumococcal conjugate vaccine·23-valent pneumococcal polysaccharide vaccine·Ofatumumab
Novartis Pharmaceuticals
Phase 3
1,882
Munich, Neuburg A.d. Donau, Unterhaching, Marburg, Cologne, Dresden, Leipzig, Barsinghausen
2018-12-28
Active, closed
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
NCT03614260Hypertension, Vascular Diseases, Cardiovascular Diseases
ReCor Medical, Inc.
Not applicable
224
Erlangen, Homburg, Karlsruhe, Konstanz, Leipzig, Lübeck
2018-12-14
Active, closed
Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial
NCT03706833Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
Edwards Lifesciences
Not applicable
1,247
Bad Oeynhausen, Cologne, Dresden, Essen, Giessen, Hamburg, Heidelberg, Leipzig
2018-11-30
Active, closed
A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in Participants With Prostate Cancer
NCT03706365Prostate Cancer
DrugsAbiraterone acetate·Abemaciclib·Prednisone
Eli Lilly and Company
Phase 2/3
393
Nürtingen, Tübingen, Holzminden, Cologne, Mettmann, Münster, Wesel, Leipzig
2018-11-26
Active, closed
Reducing Lung CongestIon Symptoms in Advanced Heart Failure
NCT03499236Heart Failure
V-Wave Ltd
Not applicable
605
Berlin, Hamburg, Leipzig, München, Remscheid, Rostock
2018-09-19
Active, closed
The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial
NCT03447938Coronary Artery Disease
Ottawa Heart Institute Research Corporation
Not applicable
176
Leipzig, Stuttgart
2018-09-01
Active, closed
International Alfapump Cohort Study
NCT04326946Liver Cirrhoses, Malignant Ascites
Sequana Medical N.V.
Observational
400
Leipzig
2018-08-14
Active, closed
A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastric Cancer.
NCT03504397Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
DrugsZolbetuximab·Folinic acid·Fluorouracil·Oxaliplatin
Astellas Pharma Global Development, Inc.
Phase 3
565
Munich, München, Mainz, Dresden, Leipzig, Halle, Magdeburg, Berlin
2018-06-21
Recruiting
Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds ("MUC-FIRE" Trial)
NCT03469609Enterostomy
University of Leipzig
Not applicable
120
Tübingen, München, Frankfurt am Main, Hanover, Witten, Mainz, Dresden, Leipzig
2018-06-18
Active, closed
Observation of Clinical Routine Care for Heart Failure Patients Implanted With BIOTRONIK CRT Devices
NCT03366545Heart Failure
Biotronik SE & Co. KG
Observational
3,030
Leipzig, Bad Berka, Bad Oeynhausen, Berlin, Brandenburg, Buchholz, Erlangen, Giessen
2018-05-14
Active, closed
Extended Access of Momelotinib in Adults With Myelofibrosis
NCT03441113Neoplasms, Post-polycythemia Vera Myelofibrosis (Post-PV MF), Primary Myelofibrosis (PMF), Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)
GlaxoSmithKline
Phase 2
237
Aachen, Cologne, Dresden, Halle, Leipzig, Lübeck, Mainz
2018-05-03
Active, closed
Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)
NCT03425643Non-small Cell Lung Cancer
DrugsPemetrexed·Keytruda·Gemcitabine·Cisplatin
Merck Sharp & Dohme LLC
Phase 3
797
Esslingen am Neckar, Immenhausen, Düsseldorf, Hemer, Rheine, Koblenz, Dresden, Leipzig
2018-04-24
Active, closed
To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.
NCT03330847Metastatic Triple Negative Breast Cancer
DrugCeralasertib
AstraZeneca
Phase 2
273
Dresden, Frankfurt am Main, Hamburg, Hanover, Leipzig, München, Witten
2018-03-07
Recruiting
Randomization of Single vs Multiple Arterial Grafts
NCT03217006Coronary Artery Disease, Heart Diseases
Weill Medical College of Cornell University
Not applicable
4,300
Duisburg, Düsseldorf, Erlangen, Giessen, Göttingen, Jena, Leipzig, Oeynhausen
2018-01-07
Active, closed
Study of IMGN632 in Patients With Untreated BPDCN and Relapsed/Refractory BPDCN
NCT03386513Blastic Plasmacytoid Dendritic Cell Neoplasm, Myeloproliferative Neoplasm
DrugIMGN632
AbbVie
Phase 1/2
179
Cologne, Leipzig
2018-01-02
Recruiting
Registry for Patients With Lipodystrophy
NCT03553420Lipodystrophy Acquired, Lipodystrophy Congenital
University of Ulm
Observational
5,000
Hanover, Leipzig, Münster, Ulm
2017-12-16
Active, closed
Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma
NCT02984410Oropharyngeal Cancer, Supraglottic Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma
European Organisation for Research and Treatment of Cancer - EORTC
Not applicable
112
Cologne, Halle, Hamburg, Jena, Leipzig, München, Tübingen, Ulm
2017-11-27
Active, closed
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
NCT02912559Colon Adenocarcinoma, DNA Repair Disorder, Lynch Syndrome, Stage III Colon Cancer AJCC v8
DrugsLeucovorin Calcium·Fluorouracil·Adrucil·Atezolizumab
National Cancer Institute (NCI)
Phase 3
712
Dresden, Berlin, Bochum, Cologne, Esslingen am Neckar, Hamburg, Leipzig, Mannheim
2017-10-16
Active, closed
Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
NCT03298451Hepatocellular Carcinoma
DrugsSorafenib·Tremelimumab·Durvalumab
AstraZeneca
Phase 3
1,324
Aachen, Cologne, Essen, Hanover, Heidelberg, Leipzig, Mainz, München
2017-10-11
Recruiting
Registry for Patients With X-Linked Hypophosphatemia
NCT03193476X-Linked Hypophosphatemia
Kyowa Kirin Pharmaceutical Development Ltd
Observational
1,489
Bad Belzig, Bochum, Cologne, Dortmund, Freiburg im Breisgau, Hanover, Leipzig, Mainz
2017-09-12
Active, closed
A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's Disease
NCT03100149Parkinson's Disease
DrugPrasinezumab
Hoffmann-La Roche
Phase 2
316
Berlin, Düsseldorf, Kassel, Leipzig, Marburg, München, Tübingen, Ulm
2017-06-27
Active, closed
Chemotherapy-free Trastuzumab and Pertuzumab in HER2-positive Breast Cancer: FDG-PET Response-adapted Strategy.
NCT03161353Breast Cancer
DrugsPerjeta·Herceptin·Tamoxifen·Pertuzumab
MedSIR
Phase 2
377
Essen, Halle, Heidelberg, Leipzig, Munich, München
2017-06-26
Active, closed
Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation
NCT03173248Newly Diagnosed Acute Myeloid Leukemia (AML), Untreated AML, AML Arising From Myelodysplastic Syndrome (MDS), Leukemia, Myeloid, Acute
DrugsIvosidenib·Azacitidine
Institut de Recherches Internationales Servier
Phase 3
146
Essen, Chemnitz, Berlin, Hanover, Leipzig, München, Ulm
2017-06-26
Active, closed
REDUCE LAP-HF TRIAL II
NCT03088033Heart Failure
Corvia Medical
Not applicable
608
Bad Nauheim, Berlin, Düsseldorf, Freiburg im Breisgau, Göttingen, Hamburg, Heidelberg, Leipzig
2017-06-01
Active, closed
LEADERS FREE II: BioFreedom™ Pivotal Study
NCT02843633Acute Coronary Syndrome, High Bleeding Risk
Biosensors Europe SA
Not applicable
1,203
Bad Segeberg, Leipzig
2017-02-14
Active, closed
An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis
NCT02808780Ulcerative Colitis
Janssen Biotech, Inc.
Observational
535
Berlin, Dessau Roblau, Halle, Hamburg, Heidelberg, Kiel, Leipzig, Ludwigshafen
2016-12-16
Active, closed
Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme
NCT02685605Glioblastoma
DrugTemozolomide
Universitätsmedizin Mannheim
Phase 3
314
Augsburg, Berlin, Leipzig, Mannheim, Munich, Stuttgart, Wuppertal
2016-12-09
Recruiting
Prospective Validation Study of the CD8+TEMRA Cells As a Prognostic Biomarker of Healing Outcome After Fracture
NCT06658379Fracture Non Union, Fracture Healing, Long Bone Delayed-Union Fracture, Humerus Shaft Fracture
Charite University, Berlin, Germany
Observational
640
Münster, Dresden, Leipzig, Berlin, Eisenberg
2016-12
Active, closed
A Longitudinal Observational Study of the Natural History and Management of Patients With HCC
NCT02954094Hepatocellular Cancer
Target PharmaSolutions, Inc.
Observational
10,000
Aachen, Berlin, Düsseldorf, Frankfurt, Hanover, Leipzig, Magdeburg, Mainz
2016-12
Recruiting
MEASuRE: Metreleptin Effectiveness And Safety Registry
NCT02325674Generalised Lipodystrophy, Partial Lipodystrophy
DrugMetreleptin
Chiesi Farmaceutici S.p.A.
Observational
100
Ulm, Hanover, Münster, Leipzig
2016-10-11
Active, closed
Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
NCT02864992Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification, Lung Adenocarcinoma Stage IIIB/IV
DrugTepotinib
EMD Serono Research & Development Institute, Inc.
Phase 2
337
Leipzig, Berlin, Chemnitz, Dresden, Erfurt, Gauting, Gera, Göttingen
2016-09-13
Active, closed
Neoadjuvant L19IL2/L19TNF- Pivotal Study
NCT02938299Malignant Melanoma
DrugsL19IL2·Onfekafusp alfa
Philogen S.p.A.
Phase 3
214
Dresden, Hanover, Heidelberg, Kiel, Leipzig, Berlin, Tübingen, Augsburg
2016-07-01
Active, closed
A Study of the ReCor Medical Paradise System in Clinical Hypertension
NCT02649426Hypertension, Vascular Diseases
ReCor Medical, Inc.
Not applicable
282
Düsseldorf, Erlangen, Freiburg im Breisgau, Homburg, Leipzig, Lübeck, Mainz
2016-03
Active, closed
Long-term Follow-up of Participants With Cerebral Adrenoleukodystrophy Who Were Treated With Lenti-D Drug Product
NCT02698579Cerebral Adrenoleukodystrophy (CALD), Adrenoleukodystrophy (ALD), X-Linked Adrenoleukodystrophy (X-ALD)
Genetix Biotherapeutics Inc.
Observational
64
Leipzig
2016-01-22
Active, closed
Study to Evaluate Imetelstat (GRN163L) in Participants With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
NCT02598661Myelodysplastic Syndromes
DrugImetelstat sodium
Geron Corporation
Phase 2/3
289
Freiburg im Breisgau, Dresden, Leipzig, Aschaffenburg, Bonn, Düsseldorf, Mainz
2016-01-12
Active, closed
A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC
NCT02489318Prostate Cancer
DrugApalutamide
Aragon Pharmaceuticals, Inc.
Phase 3
1,052
Bonn, Braunschweig, Eisleben Lutherstadt, Hamburg, Hanover, Leipzig, Lübeck, Nürtingen
2015-11-27
Recruiting
CAR-T Long Term Follow Up (LTFU) Study
NCT02445222Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
Novartis Pharmaceuticals
Phase 3
1,400
Munich, Regensburg, Würzburg, Frankfurt am Main, Cologne, Leipzig, Berlin, Hamburg
2015-11-02
Recruiting
The German ADPKD Tolvaptan Treatment Registry
NCT02497521ADPKD (Autosomal Dominant Polycystic Kidney Disease)
University of Cologne
Observational
2,000
Müllheim, Würzburg, Hanover, Cologne, Nettetal, Leipzig, Lübeck, Berlin
2015-11
Active, closed
Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS)
NCT02215265Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
DrugCisplatin
Lisette Nixon
Phase 3
1,269
Berlin, Giessen, Hamburg, Homburg, Leipzig, Potsdam, Solingen, Ulm
2015-10
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 30 September 2026. https://priyalifescience.com/clinical-trials-germany/city/leipzig?page=5

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,051 studies in total at the last sync on 26 Sep 2026, 19:51 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 511 of those studies with a site in Leipzig.

How many clinical trials are recruiting in Leipzig?

251 of the 511 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:51 UTC sync. A further 14 have not yet opened recruitment, 239 are active but closed to new participants, and 7 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.