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Priya Life Science Clinical trial register
Trackers› Clinical trials› Mild Cognitive Impairment
Clinical trial register · United States · industry-sponsored

Mild Cognitive Impairment Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9128 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 04 Nov 2026, 03:16 UTC
9128
Studies in scope
industry-sponsored, all four open statuses
4968
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
Florida 9 California 4 Georgia 3 New York 3 Colorado 2
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Phase
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Mild Cognitive Impairment trials in the USA

13 of 9128 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Not yet open
Callahan-Young LLC DBA Jigsawdio
Not applicable
80
North Carolina, Texas
2026-10
Not yet open
2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients
NCT06432166Alzheimer Disease, Mild Cognitive Impairment
MTI Biotech Inc
Phase 1/2
48
Tennessee
2026-09-01
By invitation
Software Validation Study-Cognitive Status Indicator
NCT06809725Alzheimer Disease, Mild Cognitive Impairment, Dementia
Spark Neuro Inc.
Not applicable
600
Florida
2025-03-31
Not yet open
Power Life Sciences Inc.
Observational
500
California
2025-02
Recruiting
GAP Innovations, PBC
Observational
1,200
Florida, Illinois, Michigan, Nevada, New York, Ohio, Pennsylvania, Rhode Island
2024-09-26
By invitation
Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)
NCT06245031Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia, Mild
Cognito Therapeutics, Inc.
Not applicable
402
Arizona, California, Colorado, Florida, Georgia, Illinois, Maine, Massachusetts
2024-02-29
Recruiting
Home Sleep Therapy for Older Adults With MCI
NCT05771844Mild Cognitive Impairment, Sleep, Transcranial Electrical Stimulation, Machine Learning
Brain Electrophysiology Laboratory Company
Not applicable
60
North Carolina, Oregon
2023-02-08
Active, closed
A Novel Computer-Based Functional Skills Assessment and Training Program
NCT04679441Mild Cognitive Impairment, Healthy Aging
i-Function, Inc.
Phase 2
180
Florida, New York
2021-08-01
Active, closed
Aptinyx
Phase 2
99
Arizona, California, Florida, Georgia, Michigan, Minnesota, New Jersey, New York
2019-11-14
Recruiting
Longitudinal Cognitive Assessment by BoCA
NCT04114994Alzheimer Disease, Mild Cognitive Impairment, Vascular Dementia, Frontotemporal Dementia
Alzheimer's Light LLC
Observational
10,000
Florida
2019-10-01
Active, closed
Multi-Center Study of Sensory Stimulation to Improve Brain Function
NCT03556280Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia Alzheimers
Cognito Therapeutics, Inc.
Not applicable
60
Florida, Massachusetts, New Jersey
2018-04-24
Recruiting
Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
NCT03657745Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognition Disorders in Old Age
Alzheimer's Light LLC
Observational
2,000
Florida
2018-01-01
Active, closed
Eli Lilly and Company
Observational
1,400
California, Colorado, Connecticut, Florida, Georgia, Indiana, Kansas, Kentucky
2016-10-29
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 4 November 2026. https://priyalifescience.com/clinical-trials-usa/condition/mild-cognitive-impairment

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,128 studies in total at the last sync on 04 Nov 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 13 of those studies listing the condition Mild Cognitive Impairment.

How many Mild Cognitive Impairment trials are recruiting in the US?

4 of the 13 studies on this page are recruiting new participants as of the 04 Nov 2026, 03:16 UTC sync. A further 3 have not yet opened recruitment, 4 are active but closed to new participants, and 2 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Mild Cognitive Impairment), 13 studies
PhaseStudiesRecruitingShare
Not applicable5138.5%
Observational5338.5%
Phase 22015.4%
Phase 1/2107.7%

Most active sponsors

Lead sponsors with the most studies (Mild Cognitive Impairment)
Lead sponsorStudiesRecruiting
Alzheimer's Light LLC22
Cognito Therapeutics, Inc.20
Aptinyx10
Brain Electrophysiology Laboratory Company11
Callahan-Young LLC DBA Jigsawdio10
Eli Lilly and Company10
GAP Innovations, PBC11
i-Function, Inc.10
MTI Biotech Inc10
Power Life Sciences Inc.10

Top states

Top states (Mild Cognitive Impairment), by number of studies with a site there
StateStudies
Florida9
California4
Georgia3
New York3
Arizona2
Colorado2
Illinois2
Massachusetts2
Michigan2
New Jersey2
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.