Sponsor · clinical trials

Abbott Medical Devices clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA, Italy, Germany, Spain, France, Israel, Netherlands, UK, Australia, Canada, Switzerland, Denmark, Belgium, Austria, Japan, Poland, Czechia, Portugal, Taiwan, Sweden, Ireland, India, China, Mexico, Singapore, Turkey, Brazil, South Korea and Norway registers with Abbott Medical Devices as lead sponsor. Synced 11 Nov 2026

65Current trials

27Recruiting now

1Drug in these trials

29Trial registers

Maintained by Sreepriya Prasannan

MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany

Compiled from ClinicalTrials.gov and CTIS registry records · Synced 11 Nov 2026 · Editorial standards

At a glance

Abbott Medical Devices is the lead sponsor of 65 current clinical trials in our USA, Italy, Germany, Spain, France, Israel, Netherlands, UK, Australia, Canada, Switzerland, Denmark, Belgium, Austria, Japan, Poland, Czechia, Portugal, Taiwan, Sweden, Ireland, India, China, Mexico, Singapore, Turkey, Brazil, South Korea and Norway registers. 27 are recruiting patients now. The most common phase is Not applicable. The drugs named most often in its trials are NOAC. The most-studied condition is Bradycardia.

Company profiles on this site (news, sites, medicines, approvals): Abbott Ireland (IE) →Abbott Laboratories (US) →

ClinicalTrials.gov trials by status

Recruiting2742%
Active, closed3554%
By invitation35%

Trials by phase

Not applicable3351%
Observational3249%

Clinical trials sponsored by Abbott Medical Devices

65 on ClinicalTrials.gov

Study	Phase	Status	Start	Registers
Abbott Structural Heart Device Registry NCT06590467 · Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect	Observational	Recruiting	2024-08	Ireland, UK, USA, Germany, France, Spain, Italy, Denmark, Poland
Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration NCT07523620 · Atrial Fibrillation (AF), Paroxysmal AF, Persistent Atrial Fibrillation	Not applicable	Recruiting	2026-03	Ireland, UK, Germany, Spain, Italy, Belgium, Denmark, Poland, Czechia
Left Bundle Branch Area Pacing (LBBAP) PMCF Study NCT07217392 · Bradycardia, Right Ventricular Pacing, Heart Failure	Not applicable	Recruiting	2025-07	India, Germany, France, Spain, Italy, Brazil, Singapore
LEAP 2 Chronic EFS NCT07287423 · ClinicalTrials.gov ↗ · Cardiac Pacemaker, Cardiac Rhythm Disorder, Bradycardia	Not applicable	Recruiting	2025-12	Czechia
Aveir Leadless Pacemaker Japan PMS NCT07106788 · ClinicalTrials.gov ↗ · Leadless Pacemaker	Observational	Recruiting	2025-05	Japan
CardioMEMS HF System Coverage With Evidence Development Study NCT06779552 · Heart Failure	Observational	Recruiting	2025-02	USA
Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator NCT03876054 · Chronic Pain	Observational	Recruiting	2019-03	UK, USA, Germany, Spain, Italy, Netherlands, Belgium, Switzerland, Australia
Evaluation of the DuoVT PFA System for Ventricular Tachycardia NCT07706712 · ClinicalTrials.gov ↗ · Ventricular Tachycardia	Not applicable	Recruiting	2026-09	Spain, Italy, Czechia
Navitor Japan Study NCT07193888 · ClinicalTrials.gov ↗ · Severe Aortic Stenosis	Observational	Recruiting	2025-10	Japan
Valved Graft PMCF Study NCT04754217 · Aortic Valve Disease, Ascending Aorta Abnormality, Aortic Dissection	Observational	Recruiting	2021-07	UK, USA, Germany, France, Spain, Italy, Denmark, Poland, Austria
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND) NCT06423430 · Treatment Resistant Depression	Not applicable	Recruiting	2024-09	USA, Israel
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure NCT06526195 · Heart Failure, Heart Diseases, Cardiovascular Diseases	Not applicable	Recruiting	2024-12	USA, Germany, Italy, Netherlands, Denmark, Austria, Czechia, Mexico, Israel
Abbott Vascular Medical Device Registry NCT04573660 · Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions	Observational	Recruiting	2020-10	USA, China, Germany, France, Spain, Italy, Netherlands, Belgium, Switzerland, Austria, Taiwan, Australia
Post-Market Clinical Follow Up Study With Navitor Valve NCT06008080 · Aortic Stenosis	Observational	Recruiting	2023-09	UK, Germany, France, Spain, Italy, Netherlands, Sweden, Switzerland, Portugal, Australia, Israel
Cephea Early Feasibility Study NCT05061004 · Mitral Regurgitation	Not applicable	Recruiting	2022-04	USA, Canada
Abbott DBS Post-Market Study of Outcomes for Indications Over Time NCT04071847 · Movement Disorders, Parkinson Disease, Essential Tremor	Observational	Recruiting	2019-11	UK, USA, Germany, France, Spain, Italy, Taiwan, Australia
TriClip Japan Post-Approval Study NCT07509658 · ClinicalTrials.gov ↗ · Tricuspid Regurgitation	Observational	Recruiting	2026-03	Japan
Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study NCT04761120 · Mitral Regurgitation, Tricuspid Regurgitation, Valvular Heart Disease	Observational	Recruiting	2021-02	USA, Germany, France, Spain, Italy, Netherlands
Acute Response to Left Bundle Branch Area Pacing With SyncAV NCT06436053 · ClinicalTrials.gov ↗ · Heart Failure	Observational	Recruiting	2024-05	Italy
Aveir AR Coverage With Evidence Development (CED) Study NCT06100770 · Cardiac Pacemaker, Arrhythmia, Bradycardia	Observational	Recruiting	2024-01	USA
Abbott Cephea Mitral Valve Disease Registry NCT07069673 · Mitral Regurgitation, Mitral Stenosis, Mitral Valve Disease	Observational	Recruiting	2025-08	USA
Agilis RF TSP Early Feasibility Study NCT07361445 · ClinicalTrials.gov ↗ · Cardiac Arrythmias, Left Atrial Appendage Closure	Not applicable	Recruiting	2026-02	USA
A Post-Market Assessment of the Safety and Performance of the TriClip™ System NCT07586995 · Tricuspid Regurgitation (TR)	Observational	Recruiting	2026-07	USA, Germany, France, Spain, Italy
Aveir DR Real-World Evidence Post-Approval Study NCT05935007 · Cardiac Pacemaker, Arrythmia, Bradycardia	Observational	Recruiting	2023-10	USA
ViewFlex X ICE First-in-Human Study NCT06772493 · Cardiac Arrhythmias	Observational	Recruiting	2024-12	USA
TriClip CED RWE Study NCT06920745 · Tricuspid Regurgitation	Observational	Recruiting	2025-07	USA
Grid eXplore Mapping Study NCT07421076 · ClinicalTrials.gov ↗ · Paroxysmal Atrial Fibrillation (PAF)	Not applicable	Recruiting	2026-04	China
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation NCT05932615 · Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease	Not applicable	By invitation	2024-03	UK, USA, Germany, France, Italy, Netherlands, Belgium, Sweden, Denmark, Switzerland, Canada, Australia, Israel
CardioMEMS HF System Real-World Evidence Post-Approval Study NCT06306573 · ClinicalTrials.gov ↗ · Heart Failure NYHA Class II, Heart Failure NYHA Class III	Observational	By invitation	2022-12	USA
Health App Data Collection Study NCT06595615 · Cardiac Disease	Observational	By invitation	2025-04	USA
PARADIGM: Amplatzer Valvular Plug for PVL Closure NCT04489823 · Paravalvular Aortic Regurgitation	Not applicable	Active, closed	2020-12	UK, USA, Spain, Italy, Netherlands, Poland, Canada
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial NCT03108456 · Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction	Not applicable	Active, closed	2017-03	USA, Mexico, Israel
Early Feasibility Study (EFS) of Abbott's Balloon-expandable (BE) TAVI System for the Treatment of Severe, Symptomatic Aortic Stenosis NCT07116551 · ClinicalTrials.gov ↗ · Symptomatic Severe Aortic Stenosis	Not applicable	Active, closed	2025-10	USA, France
Remote Optimization, Adjustment and Measurement for Deep Brain Stimulation NCT05269862 · Parkinson Disease	Not applicable	Active, closed	2022-03	UK, USA, Germany, Spain, Israel
Amplatzer Amulet LAAO vs. NOAC NCT04226547 · Atrial Fibrillation, Stroke, Bleeding Drug: NOAC	Not applicable	Active, closed	2020-07	UK, USA, Germany, France, Spain, Italy, Netherlands, Denmark, Poland, Switzerland, Czechia, Turkey, Canada, Mexico, Japan, Australia, Israel
Abbott Medical - VERITAS Study NCT06707688 · Atrial Fibrillation (AF), Stoke	Not applicable	Active, closed	2024-11	USA, Germany, France, Spain, Italy, Belgium, Denmark, Switzerland, Canada
Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation NCT04788888 · Symptomatic Severe Aortic Stenosis	Not applicable	Active, closed	2021-07	UK, Germany, France, Spain, Italy, Netherlands, Denmark, Switzerland, Austria, Australia, Israel
An Observational Real-world Study Evaluating Severe Tricuspid Regurgitation Patients Treated With the Abbott TriClip™ Device (bRIGHT) NCT04483089 · ClinicalTrials.gov ↗ · Tricuspid Valve Regurgitation	Observational	Active, closed	2020-08	Germany, Spain, Italy, Netherlands, Denmark, Switzerland, Austria, Portugal
Cephea South America Feasibility Study NCT07244939 · ClinicalTrials.gov ↗ · Mitral Regurgitation, Mitral Stenosis	Not applicable	Active, closed	2025-06	Brazil
BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF NCT07181590 · Paroxysmal AF, Atrial Arrhythmia, Atrial Fibrillation	Not applicable	Active, closed	2025-12	Ireland, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Denmark, Poland, Austria, Portugal
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation NCT03433274 · Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency	Not applicable	Active, closed	2018-06	USA, Canada, Israel
Amplatzer Piccolo Occluder Japan Post-marketing Database Surveillance NCT04371081 · ClinicalTrials.gov ↗ · Patent Ductus Arteriosus	Observational	Active, closed	2020-04	Japan
Portico Next Generation Approval Study NCT04011722 · Symptomatic Severe Aortic Stenosis	Not applicable	Active, closed	2019-09	UK, USA, Italy, Denmark, Australia
Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation NCT04818502 · Mitral Valve Regurgitation	Observational	Active, closed	2021-05	UK, Germany, France, Spain, Italy, Netherlands, Belgium, Switzerland, Austria, Czechia, Norway, Israel
SyncAV Post-Market Trial NCT04100148 · Congestive Heart Failure	Not applicable	Active, closed	2019-10	UK, USA, India, China, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Poland, Austria, Portugal, Canada, Japan, South Korea, Taiwan
AMPLATZER PFO Occluder Post Approval Study NCT03309332 · Stroke, Patent Foramen Ovale	Not applicable	Active, closed	2018-01	UK, USA, Germany, Italy, Switzerland, Portugal, Turkey, Canada, Israel
MitraClip EXPAND G4 Study NCT04177394 · ClinicalTrials.gov ↗ · Mitral Valve Regurgitation, Mitral Regurgitation	Observational	Active, closed	2020-01	USA, Germany, France, Spain, Italy, Netherlands, Canada, Japan, Israel
ASCEND CSP IDE Study NCT06830746 · Heart Failure, Ventricular Arrythmia	Not applicable	Active, closed	2025-04	USA, India, France, Spain, Italy, Switzerland, Canada, Singapore, Australia, Israel
Abbott Atrial Fibrillation Post Approval Study NCT05434650 · Atrial Arrhythmia, Atrium; Fibrillation, Atrial Tachycardia	Observational	Active, closed	2022-10	USA, Israel
VOLT CE Mark Study NCT06106594 · ClinicalTrials.gov ↗ · Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation	Not applicable	Active, closed	2023-10	Germany, Spain, Netherlands, Belgium, Austria, Czechia, Australia
LIFE-BTK Randomized Controlled Trial NCT04227899 · Critical Limb Ischemia (CLI)	Not applicable	Active, closed	2020-08	USA, Taiwan, Singapore, Australia
LIFE-BTK PK Sub-study NCT05208905 · Critical Limb Ischemia (CLI)	Not applicable	Active, closed	2022-02	USA, Taiwan, Australia
TRILUMINATE Pivotal Trial NCT03904147 · ClinicalTrials.gov ↗ · Tricuspid Regurgitation	Not applicable	Active, closed	2019-08	USA, Germany, Spain, Italy, Canada, Israel
MitraClip REPAIR MR Study NCT04198870 · Mitral Valve Regurgitation	Not applicable	Active, closed	2020-07	USA, Germany, Switzerland, Canada
Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial NCT02000115 · Aortic Valve Stenosis	Not applicable	Active, closed	2014-05	USA, Australia, Israel
TECTONIC CAD IVL IDE Study NCT06885177 · Coronary Artery Calcification, Coronary Artery Disease, Stenotic Coronary Lesion	Not applicable	Active, closed	2025-04	USA, Israel
Aveir VR Real-World Evidence Post-Approval Study NCT05270499 · ClinicalTrials.gov ↗ · Cardiac Pacemaker, Arrythmia, Bradycardia	Observational	Active, closed	2022-06	USA
A Clinical Evaluation of AMJ-401 NCT07373353 · ClinicalTrials.gov ↗ · Ischemic Heart Disease (IHD)	Not applicable	Active, closed	2025-12	Japan
SJM Masters HP 15mm Rotatable Mechanical Heart Valve as Aortic Valve Replacement Therapy NCT03924661 · Aortic Valve Disease	Observational	Active, closed	2019-10	USA, Germany
Esprit BTK Post-Approval Study NCT06656364 · Chronic Limb-Threatening Ischemia	Not applicable	Active, closed	2024-10	USA
XIENCE Skypoint Large Vessel Post Approval Study NCT05423379 · ClinicalTrials.gov ↗ · Coronary Artery Disease	Observational	Active, closed	2022-09	USA, France, Spain
Abbott Ventricular Tachycardia PAS NCT05839873 · Ventricular Tachycardia	Observational	Active, closed	2023-07	USA
Aveir VR Coverage With Evidence Development Post-Approval Study NCT05336877 · Cardiac Pacemaker, Arrythmia, Bradycardia	Observational	Active, closed	2022-06	USA
Amulet™ ADVANCE LAA NCT05997446 · ClinicalTrials.gov ↗ · Atrial Fibrillation, Stroke, Bleeding	Observational	Active, closed	2023-07	USA
AVEIR DR Coverage With Evidence Development (CED) Study NCT05932602 · Cardiac Pacemaker, Arrythmia, Bradycardia	Observational	Active, closed	2023-10	USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

Drugs in Abbott Medical Devices trials

1 compound

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

NOAC1

Conditions in Abbott Medical Devices trials

76 conditions

Bradycardia7Cardiac Pacemaker6Mitral Regurgitation6 Heart Failure5 Atrial Fibrillation4Arrythmia4Tricuspid Regurgitation4Atrial Arrhythmia3Persistent Atrial Fibrillation3 Atrial Fibrillation (AF)3Symptomatic Severe Aortic Stenosis3Stroke3 Aortic Valve Disease3Mitral Valve Regurgitation3Coronary Artery Disease3Paroxysmal AF2Heart Diseases2 Parkinson Disease2 Aortic Valve Stenosis2Bleeding2Mitral Stenosis2Ventricular Tachycardia2Cardiovascular Diseases2Critical Limb Ischemia (CLI)2

By trial register

Register	Trials	Recruiting
Clinical trials in USA	47	17
Clinical trials in Italy	27	13
Clinical trials in Germany	26	11
Clinical trials in Spain	25	11
Clinical trials in France	19	8
Clinical trials in Israel	17	3
Clinical trials in Netherlands	15	5
Clinical trials in UK	15	6
Clinical trials in Australia	13	4
Clinical trials in Canada	12	1
Clinical trials in Switzerland	12	3
Clinical trials in Denmark	11	4
Clinical trials in Belgium	9	3
Clinical trials in Austria	9	3
Clinical trials in Japan	8	3
Clinical trials in Poland	7	3
Clinical trials in Czechia	7	4
Clinical trials in Portugal	5	1
Clinical trials in Taiwan	5	2
Clinical trials in Sweden	4	1
Clinical trials in Ireland	3	2
Clinical trials in India	3	1
Clinical trials in China	3	2
Clinical trials in Mexico	3	1
Clinical trials in Singapore	3	1
Clinical trials in Turkey	2	0
Clinical trials in Brazil	2	1
Clinical trials in South Korea	1	0
Clinical trials in Norway	1	0

A trial with sites in more than one country appears in each of those registers.

Other sponsors in Bradycardia

Sponsor	Trials
Medtronic	4
Medtronic Cardiac Rhythm and Heart Failure	4
MicroPort CRM	2
Imperial College London	1
Klinik für Kardiologie, Pneumologie und Angiologie	1

Sponsors with the most current trials registered for this condition.

Questions about Abbott Medical Devices trials

How many clinical trials does Abbott Medical Devices sponsor?

Abbott Medical Devices is the lead sponsor of 65 current trials on ClinicalTrials.gov in our USA, Italy, Germany, Spain, France, Israel, Netherlands, UK, Australia, Canada, Switzerland, Denmark, Belgium, Austria, Japan, Poland, Czechia, Portugal, Taiwan, Sweden, Ireland, India, China, Mexico, Singapore, Turkey, Brazil, South Korea and Norway registers, as of the registry sync on 11 November 2026. Completed and withdrawn studies are not counted.

Are Abbott Medical Devices trials recruiting?

Yes. 27 of its 65 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Abbott Medical Devices testing?

Its current trials name 1 drug or biological as interventions. The most frequent are NOAC (1). The number in brackets is how many of its trials name each drug.

Does Abbott Medical Devices have clinical trials in Ireland?

Yes. 3 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, lead sponsor, phase, overall status, start date, conditions and intervention names
EU Clinical Trials Information System (CTIS) ↗ EU trial numbers, titles, sponsor, phase, status, therapeutic area and member-state countries

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 11 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.