| Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza NICE TA158 | Amantadine, Oseltamivir | Not recommended Recommended | 24 Sep 2008 | Current |
| Dabigatran etexilate for preventing venous thromboembolism after hip or knee replacement surgery NICE TA157 | Dabigatran Etexilate | Recommended | 24 Sep 2008 | Current |
| Routine antenatal anti-D prophylaxis for women who are rhesus D negative NICE TA156 | — | Recommended | 27 Aug 2008 | Current |
| Ranibizumab and pegaptanib for the treatment of age-related macular degeneration NICE TA155 | Ranibizumab | Recommended Not recommended | 27 Aug 2008 Updated 20 May 2024 | Current |
| Entecavir for the treatment of chronic hepatitis B NICE TA153 | Entecavir | Recommended | 27 Aug 2008 | Current |
| Drug-eluting stents for the treatment of coronary artery disease NICE TA152 | — | Optimised | 23 Jul 2008 Updated 18 Nov 2020 | Current |
| Continuous subcutaneous insulin infusion for the treatment of diabetes mellitus NICE TA151 | — | Optimised | 23 Jul 2008 | Current |
| Adalimumab for treating moderate to severe plaque psoriasis NICE TA146 | Adalimumab | Recommended | 25 Jun 2008 | Current |
| Cetuximab for the treatment of locally advanced squamous cell cancer of the head and neck NICE TA145 | Cetuximab | Optimised | 25 Jun 2008 | Current |
| Rimonabant for the treatment of overweight and obese adults NICE TA144 | — | Optimised | 23 Jun 2008 | Current |
| Adalimumab, etanercept and infliximab for ankylosing spondylitis NICE TA143 | Adalimumab, Etanercept, Infliximab | Recommended Not recommended | 28 May 2008 | Replaced by TA383 |
| Epoetin alfa, epoetin beta and darbepoetin alfa for cancer treatment-induced anaemia NICE TA142 | — | Optimised | 28 May 2008 | Replaced by TA323 |
| Continuous positive airway pressure for the treatment of obstructive sleep apnoea/hypopnoea syndrome NICE TA139 | — | Recommended | 26 Mar 2008 Updated 20 Aug 2021 | Current |
| Inhaled corticosteroids for the treatment of chronic asthma in adults and in children aged 12 years and over NICE TA138 | Budesonide | Recommended | 26 Mar 2008 | Current |
| Rituximab for the treatment of relapsed or refractory stage 3 or 4 follicular non-Hodgkin's lymphoma NICE TA137 | Rituximab | Recommended | 27 Feb 2008 | Current |
| Pemetrexed for the treatment of malignant pleural mesothelioma NICE TA135 | Pemetrexed | Recommended | 23 Jan 2008 | Current |
| Infliximab for treating moderate to severe plaque psoriasis NICE TA134 | — | Optimised | 23 Jan 2008 | Current |
| Omalizumab for severe persistent allergic asthma NICE TA133 | Omalizumab | Recommended | 28 Nov 2007 | Replaced |
| Ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia NICE TA132 | Ezetimibe | Recommended | 28 Nov 2007 | Current |
| Inhaled corticosteroids for the treatment of chronic asthma in children under the age of 12 years NICE TA131 | Budesonide | Recommended | 28 Nov 2007 | Current |
| Adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis NICE TA130 | Adalimumab, Etanercept, Infliximab | Not recommended Optimised | 22 Oct 2007 | Replaced by TA375 |
| Bortezomib monotherapy for relapsed multiple myeloma NICE TA129 | Bortezomib | Recommended | 23 Oct 2007 | Current |
| Stapled haemorrhoidopexy for the treatment of haemorrhoids NICE TA128 | — | Recommended | 26 Sep 2007 | Current |
| Natalizumab for treating rapidly evolving severe relapsing–remitting multiple sclerosis NICE TA127 | Natalizumab | Optimised | 22 Aug 2007 Updated 21 May 2024 | Current |
| Rituximab for the treatment of rheumatoid arthritis NICE TA126 | Rituximab | Recommended | 22 Aug 2007 | Current |
| Adalimumab for the treatment of psoriatic arthritis NICE TA125 | Adalimumab | Recommended | 22 Aug 2007 | Current |
| Varenicline for smoking cessation NICE TA123 | Varenicline | Recommended | 25 Jul 2007 | Current |
| Alteplase for the treatment of acute ischaemic stroke NICE TA122 | Alteplase | Recommended | 27 Jun 2007 | Replaced by TA264 |
| Carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma NICE TA121 | Temozolomide | Recommended | 27 Jun 2007 | Current |
| Cardiac resynchronisation therapy for the treatment of heart failure NICE TA120 | — | Recommended | 23 May 2007 | Replaced by TA314 |
| Cinacalcet for the treatment of secondary hyperparathyroidism in patients with end-stage renal disease on maintenance dialysis therapy NICE TA117 | — | Optimised | 24 Jan 2007 | Current |
| Gemcitabine for the treatment of metastatic breast cancer NICE TA116 | Gemcitabine | Recommended | 24 Jan 2007 | Current |
| Naltrexone for the management of opioid dependence NICE TA115 | Naltrexone | Recommended | 24 Jan 2007 | Current |
| Methadone and buprenorphine for the management of opioid dependence NICE TA114 | Buprenorphine, Methadone | Recommended | 24 Jan 2007 | Current |
| Inhaled insulin for the treatment of type 1 and type 2 diabetes NICE TA113 | — | Optimised | 13 Dec 2006 | Current |
| Hormonal therapies for the adjuvant treatment of early oestrogen-receptor-positive breast cancer NICE TA112 | Anastrozole, Exemestane, Letrozole | Recommended | 22 Nov 2006 | Current |
| Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease NICE TA111 | Donepezil, Galantamine, Memantine | Optimised Only in research | 22 Nov 2006 | Current |
| Rituximab for the treatment of follicular lymphoma NICE TA110 | Rituximab | Recommended | 27 Sep 2006 | Replaced by TA243 |
| Docetaxel for the adjuvant treatment of early node-positive breast cancer NICE TA109 | Docetaxel | Recommended | 26 Sep 2006 | Current |
| Trastuzumab for the adjuvant treatment of early-stage HER2-positive breast cancer NICE TA107 | Trastuzumab | Recommended | 23 Aug 2006 | Current |
| Peginterferon alfa and ribavirin for the treatment of mild chronic hepatitis C NICE TA106 | Peginterferon alfa-2b | Recommended | 23 Aug 2006 Updated 27 Nov 2013 | Current |
| Laparoscopic surgery for colorectal cancer NICE TA105 | — | Recommended | 23 Aug 2006 | Current |
| Etanercept and infliximab for the treatment of psoriatic arthritis NICE TA104 | Etanercept, Infliximab | Recommended Optimised | 26 Jul 2006 | Replaced by TA199 |
| Etanercept and efalizumab for treating moderate to severe plaque psoriasis NICE TA103 | Etanercept | Optimised Recommended | 26 Jul 2006 Updated 1 Sep 2009 | Current |
| Parent-training/education programmes in the management of children with conduct disorders NICE TA102 | — | Recommended | 26 Jul 2006 | Current |
| Docetaxel for the treatment of hormone-refractory metastatic prostate cancer NICE TA101 | Docetaxel | Recommended | 28 Jun 2006 | Current |
| Capecitabine and oxaliplatin in the adjuvant treatment of stage 3 (Dukes' C) colon cancer NICE TA100 | Capecitabine, Oxaliplatin | Recommended | 26 Apr 2006 | Current |
| Immunosuppressive therapy for renal transplantation in children and adolescents NICE TA99 | Basiliximab, Sirolimus, Tacrolimus, Mycophenolate Mofetil | Not recommended Recommended Optimised | 26 Apr 2006 | Current |
| Methylphenidate, atomoxetine and dexamfetamine for attention deficit hyperactivity disorder (ADHD) in children and adolescents NICE TA98 | Atomoxetine, Methylphenidate | Recommended | 22 Mar 2006 | Current |
| Computerised cognitive behaviour therapy for depression and anxiety NICE TA97 | — | Not recommended Recommended Only in research | 22 Feb 2006 | Withdrawn |
| Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis B NICE TA96 | — | Optimised Recommended | 22 Feb 2006 | Current |
| Implantable cardioverter defibrillators for arrhythmias NICE TA95 | — | Recommended | 25 Jan 2006 | Replaced by TA314 |
| Statins for the prevention of cardiovascular events NICE TA94 | Atorvastatin, Pravastatin, Rosuvastatin, Simvastatin | Recommended | 25 Jan 2006 | Current |
| Colorectal cancer (advanced) - irinotecan, oxaliplatin and raltitrexed NICE TA93 | Irinotecan, Oxaliplatin, Raltitrexed | Recommended Only in research | 24 Aug 2005 | Current |
| Paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan for second-line or subsequent treatment of advanced ovarian cancer NICE TA91 | Pegylated liposomal doxorubicin, Topotecan, Paclitaxel | Recommended | 25 May 2005 | Replaced by TA389 |
| Clopidogrel and modified-release dipyridamole in the prevention of occlusive vascular events NICE TA90 | Dipyridamole, Clopidogrel | Optimised | 25 May 2005 | Current |
| Dual‑chamber pacemakers for symptomatic bradycardia due to sick sinus syndrome and/or atrioventricular block NICE TA88 | — | Recommended | 23 Feb 2005 Updated 1 Nov 2014 | Current |
| The clinical effectiveness and cost effectiveness of technologies for the secondary prevention of osteoporotic fractures in postmenopausal women NICE TA87 | Alendronate, Etidronate, Teriparatide | Optimised | 26 Jan 2005 | Current |
| Imatinib for the treatment of unresectable and/or metastatic gastro-intestinal stromal tumours NICE TA86 | Imatinib | Recommended | 27 Oct 2004 Updated 1 Nov 2010 | Current |
| Immunosuppressive therapy for renal transplantation in adults NICE TA85 | Mycophenolate Mofetil, Sirolimus, Tacrolimus | Recommended Optimised | 22 Sep 2004 | Replaced by TA481 |
| Drotrecogin alfa (activated) for severe sepsis NICE TA84 | — | Recommended | 22 Sep 2004 | Current |
| Laparoscopic surgery for inguinal hernia repair NICE TA83 | — | Recommended | 22 Sep 2004 | Current |
| Tacrolimus and pimecrolimus for atopic eczema NICE TA82 | Pimecrolimus, Tacrolimus | Recommended | 25 Aug 2004 | Current |
| Frequency of application of topical corticosteroids for atopic eczema NICE TA81 | Clobetasol Propionate, Fluticasone propionate, Hydrocortisone, Mometasone furoate | Recommended | 25 Aug 2004 | Current |
| Clopidogrel in the treatment of non-ST-segment-elevation acute coronary syndrome NICE TA80 | Clopidogrel | Optimised | 28 Jul 2004 | Replaced |
| Newer drugs for epilepsy in children NICE TA79 | Gabapentin, Lamotrigine, Topiramate | Recommended | 28 Apr 2004 | Current |
| Fluid-filled thermal balloon and microwave endometrial ablation techniques for heavy menstrual bleeding NICE TA78 | — | Recommended | 28 Apr 2004 | Current |
| Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia NICE TA77 | — | Recommended | 28 Apr 2004 | Current |
| Newer drugs for epilepsy in adults NICE TA76 | Gabapentin, Lamotrigine, Levetiracetam, Topiramate | Recommended | 24 Mar 2004 | Current |
| Interferon alfa (pegylated and non-pegylated) and ribavirin for the treatment of chronic hepatitis C NICE TA75 | — | Recommended | 28 Jan 2004 Updated 27 Nov 2013 | Current |
| Pre-hospital initiation of fluid replacement therapy in trauma NICE TA74 | — | Recommended | 28 Jan 2004 | Current |
| Myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarction NICE TA73 | — | Recommended | 26 Nov 2003 Updated 1 Jul 2011 | Current |
| Guidance on the use of coronary artery stents NICE TA71 | — | Recommended Optimised | 22 Oct 2003 Updated 18 Nov 2020 | Current |
| Guidance on the use of imatinib for chronic myeloid leukaemia NICE TA70 | Imatinib | Recommended | 22 Oct 2003 Updated 21 Jan 2016 | Current |
| Guidance on the use of liquid-based cytology for cervical screening NICE TA69 | — | Recommended | 22 Oct 2003 | Current |
| Guidance on the use of photodynamic therapy for age-related macular degeneration NICE TA68 | — | Optimised | 24 Sep 2003 | Current |
| The clinical effectiveness and cost effectiveness of amantadine and oseltamivir for the prophylaxis of influenza NICE TA67 | Amantadine, Oseltamivir | Not recommended Recommended | 24 Sep 2003 | Current |
| The clinical effectiveness and cost effectiveness of new drugs for bipolar disorder NICE TA66 | Olanzapine | Recommended | 24 Sep 2003 | Current |
| Rituximab for aggressive non-Hodgkin's lymphoma NICE TA65 | Rituximab | Recommended Only in research | 24 Sep 2003 | Current |
| Human growth hormone (somatropin) in adults with growth hormone deficiency NICE TA64 | Somatropin | Optimised | 27 Aug 2003 | Current |
| Glitazones in the treatment of type 2 diabetes NICE TA63 | Pioglitazone | Optimised | 27 Aug 2003 | Current |
| Guidance on the use of capecitabine for the treatment of locally advanced or metastatic breast cancer NICE TA62 | Capecitabine | Recommended | 28 May 2003 | Current |
| Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancer NICE TA61 | Capecitabine, Tegafur | Recommended | 27 May 2003 | Current |
| Guidance on the use of patient-education models for diabetes NICE TA60 | — | Recommended | 26 Apr 2003 Updated 1 Aug 2015 | Replaced |
| Guidance on the use of electroconvulsive therapy NICE TA59 | — | Optimised | 26 Apr 2003 Updated 1 Oct 2009 | Current |
| Flu treatment - zanamivir, amantadine and oseltamivir NICE TA58 | Amantadine, Oseltamivir | Not recommended Recommended | 26 Feb 2003 | Current |
| The clinical effectiveness and cost effectiveness of insulin pump therapy NICE TA57 | — | Optimised Not recommended | 26 Feb 2003 | Current |
| The clinical effectiveness and cost effectiveness of tension-free vaginal tape for stress incontinence NICE TA56 | — | Recommended | 26 Feb 2003 | Current |
| Guidance on the use of paclitaxel in the treatment of ovarian cancer NICE TA55 | Paclitaxel | Recommended | 22 Jan 2003 Updated 1 May 2005 | Current |
| Guidance on the use of vinorelbine for the treatment of advanced breast cancer NICE TA54 | Vinorelbine | Not recommended Recommended | 13 Dec 2002 | Current |
| Guidance on the use of long‑acting insulin analogues for the treatment of diabetes – insulin glargine NICE TA53 | Insulin glargine | Recommended Optimised | 6 Dec 2002 Updated 1 Aug 2015 | Replaced |
| Guidance on the use of drugs for early thrombolysis in the treatment of acute myocardial infarction NICE TA52 | Alteplase, Tenecteplase | Recommended | 30 Oct 2002 | Current |
| Imanitib for chronic myeloid leukaemia NICE TA50 | Imatinib | Recommended | 16 Oct 2002 | Replaced by TA70 |
| Guidance on the use of ultrasound locating devices for placing central venous catheters NICE TA49 | — | Not recommended Optimised | 4 Oct 2002 | Current |
| Guidance on home compared with hospital haemodialysis for patients with end-stage renal failure NICE TA48 | — | Recommended | 26 Sep 2002 | Current |
| Guidance on the use of glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromes NICE TA47 | Tirofiban | Recommended | 5 Sep 2002 Updated 1 Mar 2010 | Current |
| The clinical effectiveness and cost effectiveness of surgery for people with morbid obesity NICE TA46 | — | Recommended | 19 Jul 2002 | Current |
| Ovarian cancer (advanced) - paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan NICE TA45 | Pegylated liposomal doxorubicin | Recommended | 19 Jul 2002 | Current |
| The clinical effectiveness and cost effectiveness of newer atypical antipsychotic drugs for schizophrenia NICE TA43 | Olanzapine, Quetiapine, Risperidone | Recommended | 26 Jun 2002 | Current |
| Human growth hormone for the treatment growth failure in children NICE TA42 | Somatropin | Recommended | 27 May 2002 | Current |
