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Compound · clinical trials

Levofolinate clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 4 trials in our Japan register that name Levofolinate as an intervention. Synced 26 Sep 2026
4Current trials
1Recruiting now
2Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Levofolinate is named as an intervention in 4 current clinical trials in our Japan register. 1 is recruiting patients now. The most common phase is Phase 1. The sponsor with the most trials is Ono Pharmaceutical Co., Ltd (2). The most-studied condition is Metastatic Pancreatic Cancer.

Trials by status

  • Recruiting125%
  • Active, closed375%

Trials by phase

  • Phase 1250%
  • Phase 2250%
01

Clinical trials of Levofolinate

4 trials
StudyPhaseStatusLead sponsorRegisters
An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma
NCT07018570 · ClinicalTrials.gov ↗ · Gastroesophageal Junction (GEJ) Adenocarcinoma
Phase 2 Recruiting National Cancer Center Hospital East Japan
An Open Label Phase 2 Study to Evaluate the Safety and Efficacy of Lenvatinib With Pembrolizumab or Lenvatinib, Pembrolizumab and FLOT in the Neoadjuvant / Adjuvant Treatment for Patients With Gastric Cancer
NCT04745988 · ClinicalTrials.gov ↗ · Gastric Cancer
Phase 2 Active, closed National Cancer Center Hospital East Japan
An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic Cancer
NCT06532344 · ClinicalTrials.gov ↗ · Metastatic Pancreatic Cancer
Phase 1 Active, closed Ono Pharmaceutical Co., Ltd Japan
The Study of ONO-7913, ONO-4538 and the Standard of Care as First-line Treatment in Patients Colorectal Cancer
NCT06540261 · ClinicalTrials.gov ↗ · Unresectable Colorectal Cancer
Phase 1 Active, closed Ono Pharmaceutical Co., Ltd Japan

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Levofolinate

4 conditions
Metastatic Pancreatic Cancer1Gastroesophageal Junction (GEJ) Adenocarcinoma1Unresectable Colorectal Cancer1Gastric Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Ono Pharmaceutical Co., Ltd2
National Cancer Center Hospital East2
04

By country register

RegisterTrialsRecruiting
Clinical trials in Japan41

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Levofolinate trials

How many clinical trials are testing Levofolinate?

4 current trials in our Japan register name Levofolinate as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Levofolinate trials recruiting patients?

Yes. 1 of the 4 trials is recruiting: 1 with sites in Japan. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Levofolinate clinical trials?

Ono Pharmaceutical Co., Ltd (2) and National Cancer Center Hospital East (2). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Levofolinate works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Levofolinate works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Levofolinate (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.