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Priya Life Science Clinical trial register
Trackers› Clinical trials› Primary Myelofibrosis
Clinical trial register · United States · industry-sponsored

Primary Myelofibrosis Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9128 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 04 Nov 2026, 03:16 UTC
9128
Studies in scope
industry-sponsored, all four open statuses
4968
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 7 Florida 6 Alabama 4 Arizona 4 Michigan 4
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Recruitment status
Phase
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Primary Myelofibrosis trials in the USA

10 of 9128 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk
NCT06468033Primary Myelofibrosis, Myeloproliferative Neoplasm
PharmaEssentia
Phase 3
160
California, District of Columbia, Kansas, Maryland, Missouri, New York, North Carolina, Ohio
2025-07-18
Recruiting
Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis
NCT06517875Primary Myelofibrosis, Myelofibrosis; Primary Myelofibrosis; Post-polycythemia Vera Myelofibrosis; Post-essential Thrombocythemia Myelofibrosis
GlaxoSmithKline
Phase 2
68
Michigan, New York, Tennessee, Texas, Washington
2025-02-28
Recruiting
Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Phase 1
256
California, Florida, Kansas, Massachusetts, Michigan, Missouri, New York, North Carolina
2024-10-03
Recruiting
Kartos Therapeutics, Inc.
Phase 3
600
Alabama, Arizona, California, Colorado, Delaware, District of Columbia, Florida, Iowa
2024-06-03
Recruiting
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
NCT06351631Thrombocythemia, Essential, Primary Myelofibrosis, Myelofibrosis, Post-polycythemia Vera Myelofibrosis
Merck Sharp & Dohme LLC
Phase 3
400
Michigan, North Carolina, Ohio, Pennsylvania
2024-05-23
Recruiting
Telios Pharma, Inc.
Phase 1/2
70
Alabama, Ohio, Texas
2022-06-09
Active, closed
Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2)
NCT04603495Myelofibrosis, Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
Novartis Pharmaceuticals
Phase 3
430
Alabama, Arizona, California, Connecticut, Florida, Illinois, Indiana, Kentucky
2021-04-09
Active, closed
Celgene
Phase 3
313
California, Florida, Illinois, Kentucky, Michigan, Missouri, New Jersey, New York
2021-02-25
Active, closed
GlaxoSmithKline
Phase 2
237
Arizona, California, Colorado, Florida, Georgia, Maryland, Massachusetts, Minnesota
2018-05-03
Active, closed
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis
NCT03165734Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
Swedish Orphan Biovitrum
Phase 3
407
Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Illinois
2017-06-26
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 4 November 2026. https://priyalifescience.com/clinical-trials-usa/condition/primary-myelofibrosis

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,128 studies in total at the last sync on 04 Nov 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 10 of those studies listing the condition Primary Myelofibrosis.

How many Primary Myelofibrosis trials are recruiting in the US?

5 of the 10 studies on this page are recruiting new participants as of the 04 Nov 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 5 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Primary Myelofibrosis), 10 studies
PhaseStudiesRecruitingShare
Phase 36260%
Phase 22120%
Phase 11110%
Phase 1/21110%

Most active sponsors

Lead sponsors with the most studies (Primary Myelofibrosis)
Lead sponsorStudiesRecruiting
GlaxoSmithKline21
Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company11
Celgene10
Kartos Therapeutics, Inc.11
Merck Sharp & Dohme LLC11
Novartis Pharmaceuticals10
PharmaEssentia10
Swedish Orphan Biovitrum10
Telios Pharma, Inc.11

Top states

Top states (Primary Myelofibrosis), by number of studies with a site there
StateStudies
California7
Florida6
Alabama4
Arizona4
Michigan4
New York4
Colorado3
District of Columbia3
Illinois3
Missouri3
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.