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Priya Life Science Clinical trial register
Trackers› Clinical trials› Neovascular Age-related Macular Degeneration
Clinical trial register · United States · industry-sponsored

Neovascular Age-related Macular Degeneration Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9141 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 18 Oct 2026, 03:16 UTC
9141
Studies in scope
industry-sponsored, all four open statuses
4966
Recruiting now
open to new participants
2196
Lead sponsors
across recruiting studies
Top states
California 14 Florida 12 Illinois 11 Colorado 9 Arizona 9
Narrow the registerReset
Recruitment status
Phase
Target enrolment
to

Neovascular Age-related Macular Degeneration trials in the USA

16 of 9141 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Amgen
Phase 3
304
California, Colorado, Connecticut, Florida, Illinois, Indiana, Maryland, Massachusetts
2026-05-27
Recruiting
AbbVie
Phase 3
561
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa
2025-11-05
Active, closed
Ocular Therapeutix, Inc.
Phase 3
825
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana
2024-11-27
Active, closed
Sanofi
Phase 1/2
66
Arizona, California, Florida, Georgia, Illinois, Maryland, Massachusetts, Nevada
2024-11-21
Active, closed
Regeneron Pharmaceuticals
Phase 3
1,126
California, Colorado, Connecticut, Florida, Georgia, Hawaii, Illinois, Maryland
2024-07-24
Recruiting
Skyline Therapeutics (US) Inc.
Phase 1/2
68
Florida, Massachusetts, Texas, Virginia
2024-02-23
Active, closed
Ocular Therapeutix, Inc.
Phase 3
344
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana
2024-01-29
Active, closed
AiViva BioPharma, Inc.
Phase 1
19
California, Oregon, Texas
2023-03-02
Active, closed
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
NCT05476926Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Branch Retinal Vein Occlusion
Hoffmann-La Roche
Observational
6,000
Arizona, California, Florida, Illinois, Kentucky, Maryland, Michigan, Pennsylvania
2022-11-21
Active, closed
Safety, Tolerability and PK of Subcutaneous D-4517.2 in Subjects With Wet AMD or DME
NCT05387837Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Ashvattha Therapeutics, Inc.
Phase 2
50
California, Illinois, Indiana, Maryland, Massachusetts, Missouri, New Jersey, Pennsylvania
2022-08-31
Active, closed
Adverum Biotechnologies, Inc.
Phase 2
69
Arizona, California, Colorado, Connecticut, Florida, Hawaii, Michigan, Mississippi
2022-08-23
Recruiting
Genentech, Inc.
Phase 4
188
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Iowa
2021-12-14
Active, closed
A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders
NCT05112861Age-Related Macular Degeneration, Neovascular Age-related Macular Degeneration, Wet Macular Degeneration, BRVO - Branch Retinal Vein Occlusion
Outlook Therapeutics, Inc.
Phase 3
120
Illinois, Maryland, Pennsylvania
2021-11-15
Active, closed
Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]
NCT04645212Wet Age-related Macular Degeneration, Neovascular Age-related Macular Degeneration
Adverum Biotechnologies, Inc.
Observational
23
California, Colorado, Florida, Nevada, Pennsylvania, Tennessee, Texas
2020-12-14
By invitation
Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy
NCT03999801Neovascular Age-related Macular Degeneration, Wet Macular Degeneration
AbbVie
Phase 2
865
Arizona, California, Maryland, Massachusetts, Nevada, Pennsylvania, Tennessee, Texas
2019-05-31
Recruiting
Hoffmann-La Roche
Phase 3
1,000
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Iowa
2018-09-20
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 18 October 2026. https://priyalifescience.com/clinical-trials-usa/condition/neovascular-age-related-macular-degeneration

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,141 studies in total at the last sync on 18 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 16 of those studies listing the condition Neovascular Age-related Macular Degeneration.

How many Neovascular Age-related Macular Degeneration trials are recruiting in the US?

5 of the 16 studies on this page are recruiting new participants as of the 18 Oct 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 10 are active but closed to new participants, and 1 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Neovascular Age-related Macular Degeneration), 16 studies
PhaseStudiesRecruitingShare
Phase 37343.8%
Phase 23018.8%
Observational2012.5%
Phase 1/22112.5%
Phase 1106.3%
Phase 4116.3%

Most active sponsors

Lead sponsors with the most studies (Neovascular Age-related Macular Degeneration)
Lead sponsorStudiesRecruiting
AbbVie21
Adverum Biotechnologies, Inc.20
Hoffmann-La Roche21
Ocular Therapeutix, Inc.20
AiViva BioPharma, Inc.10
Amgen11
Ashvattha Therapeutics, Inc.10
Genentech, Inc.11
Outlook Therapeutics, Inc.10
Regeneron Pharmaceuticals10

Top states

Top states (Neovascular Age-related Macular Degeneration), by number of studies with a site there
StateStudies
California14
Florida12
Illinois11
Arizona9
Colorado9
Connecticut7
Georgia7
Maryland7
Indiana5
Massachusetts5
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.