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Trackers› Clinical trials› California
Clinical trial register · United States · industry-sponsored

Clinical Trials in California, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9132 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 12 Oct 2026, 03:16 UTC
9132
Studies in scope
industry-sponsored, all four open statuses
4964
Recruiting now
open to new participants
2194
Lead sponsors
across recruiting studies
Top states
California 33 Florida 28 Texas 22 Colorado 20 Illinois 16
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
GRAIL, Inc.3 MBrace Therapeutics1 Exai Bio Inc.1 Actuate Therapeutics Inc.1 Conjupro Biotherapeutics, Inc.1
State
California33 Florida28 Texas22 Colorado20 Illinois16
All 41 states
Target enrolment
to

Trials with a site in California

33 of 9132 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
By invitation
Certis Oncology Solutions, Inc
Observational
40
California
2025-12-11
Recruiting
Harbinger Health
Observational
2,450
California, Colorado, Florida, Georgia, Illinois, Iowa, Kansas, Louisiana
2025-07-11
Active, closed
A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
NCT06533059Cancer, Breast Cancer, Endometrial Cancer, Metastatic Cancer
Alterome Therapeutics, Inc.
Phase 1
110
California, Colorado, Florida, Massachusetts, Missouri, Tennessee, Texas, Virginia
2024-08-22
Recruiting
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
NCT06440005Cancer, Advanced Cancer, Locally Advanced Carcinoma, Metastatic Solid Tumor
Angiex, Inc.
Phase 1
80
California, Florida, Missouri, Tennessee, Texas, Virginia
2024-07-22
Recruiting
GRAIL, Inc.
Not applicable
50,000
Arkansas, California, Florida, Georgia, Indiana, Louisiana, Missouri, Oregon
2024-07-12
Recruiting
Tempus AI
Observational
500
Alabama, California, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky
2024-06-26
Recruiting
MBrace Therapeutics
Phase 1/2
130
California, Colorado, Georgia, Illinois, Indiana, Michigan, Nevada, New Jersey
2023-11-07
Recruiting
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
NCT05970497Cancer, Melanoma Stage III, Melanoma Stage IV, Cutaneous Melanoma
DrugsKB707·Opdualag·Keytruda·Pembrolizumab
Krystal Biotech, Inc.
Phase 1/2
240
California, Florida, Indiana, Michigan, Nebraska, New Jersey, New York, Ohio
2023-10-31
Recruiting
Exai Bio Inc.
Observational
2,400
California, Nevada
2023-07-14
Active, closed
Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02)
NCT05520099Immunotherapy, Cancer, Bladder Cancer, Urothelial Carcinoma Bladder
Elephas
Observational
416
Arkansas, California, Florida, Kentucky, Maryland, New Jersey, New York, North Carolina
2023-06-26
Recruiting
Conjupro Biotherapeutics, Inc.
Phase 1
132
California, Colorado, Florida, New Hampshire, Pennsylvania, Tennessee, Texas, Virginia
2023-06-06
Recruiting
FOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT05919264Cancer, Colorectal Cancer, Solid Tumor, Locally Advanced Solid Tumor
DrugsLonsurf·MFOLFOX6·Trifluridine/Tipiracil·Avastin
Parabilis Medicines, Inc.
Phase 1/2
619
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Maryland, Massachusetts
2023-05-23
Active, closed
DEKA Biosciences
Phase 1
39
California, New York, Oklahoma, Texas, Virginia
2023-04-03
Active, closed
Nectin Therapeutics Ltd
Phase 1
90
California, Louisiana, Texas
2022-09-01
Recruiting
N-Power Medicine
Observational
20,000
California, Delaware, Illinois, New Mexico, Pennsylvania, Texas
2022-08-01
By invitation
AstraZeneca
Phase 3
214
California, Colorado, Tennessee
2022-04-19
Recruiting
Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System
NCT05406167Cancer, Cancer Central Nervous System, Cancer Thoracic, Cancer, Gastrointestinal
RefleXion Medical
Observational
500
California, Connecticut, Pennsylvania, Texas
2022-04-12
Recruiting
Phase I Human Analytics (HALO) Study
NCT05423860Cardiovascular Diseases, Cancer, Dementia, Traumatic Brain Injury
HALO Diagnostics
Observational
2,000
California
2022-03-16
Active, closed
PATHFINDER 2: A Multi-Cancer Early Detection Study
NCT05155605Early Detection of Cancer, Cancer
GRAIL, Inc.
Not applicable
35,883
California, Colorado, District of Columbia, Florida, Georgia, Illinois, Louisiana, Maryland
2021-12-08
Active, closed
REFLECTION: A Clinical Practice Learning Program for Galleri®
NCT05205967Early Detection of Cancer, Cancer
GRAIL, Inc.
Observational
14,633
Arizona, California, Florida, Louisiana, Massachusetts, Oregon, Pennsylvania, South Carolina
2021-08-23
Active, closed
A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors
NCT04673942Solid Tumor, Adult, Cancer, Neoplasms, Sarcoma
EpicentRx, Inc.
Phase 2
140
California, Ohio, Texas
2021-03-29
Active, closed
Bayer
Phase 3
402
Alabama, Arizona, California, Colorado, Florida, Illinois, Kentucky, Maryland
2020-10-20
Active, closed
Tizona Therapeutics, Inc
Phase 1
240
Arizona, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Illinois
2020-07-14
Active, closed
Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies
NCT04349436Merkel Cell Carcinoma, Basal Cell Carcinoma, Locally Advanced Cutaneous Squamous Cell Carcinoma, Cancer
Replimune, Inc.
Phase 1/2
69
Arizona, California, Colorado, Florida, Massachusetts, Minnesota, Missouri, New York
2020-05-15
Recruiting
Trial of DFP-14927 in Advanced Solid Tumors
NCT03943004Solid Tumor, Cancer
Delta-Fly Pharma, Inc.
Phase 1
30
California, Texas
2019-09-30
Recruiting
Bristol-Myers Squibb
Phase 2
1,500
Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Illinois
2019-08-09
Recruiting
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
NCT05181826Cancer, Liver Cirrhosis, Chronic Hepatitis, Hepatitis B
Helio Genomics
Observational
1,200
California, Minnesota, Tennessee, Texas
2019-05-21
Active, closed
AbbVie
Phase 1
150
Arkansas, California, Connecticut, Florida, Indiana, Missouri, North Carolina, Pennsylvania
2019-05-21
Recruiting
Immatics US, Inc.
Phase 1/2
375
California, Colorado, Florida, Illinois, Massachusetts, New York, Ohio, Pennsylvania
2019-05-14
Active, closed
9-ING-41 in Patients With Advanced Cancers
NCT03678883Cancer, Pancreatic Cancer, Sarcoma, Renal Cancer
DrugsCCNU·Lomustine·Abraxane·Adriamycin
Actuate Therapeutics Inc.
Phase 2
350
Arizona, California, Delaware, District of Columbia, Florida, Illinois, Iowa, Kansas
2019-01-04
By invitation
Compliant Analysis of Patient Samples and Data
NCT04364503Pregnancy Related, Cancer, Infectious Disease
Sequenom, Inc.
Observational
2,000
California, Colorado, Illinois, New York, North Carolina
2018-03-17
Recruiting
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver
Massive Bio, Inc.
Observational
50,000
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida
2018-01-01
Active, closed
Hoffmann-La Roche
Phase 3
382
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2017-09-20
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 October 2026. https://priyalifescience.com/clinical-trials-usa/state/california

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,132 studies in total at the last sync on 12 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 33 of those studies with a site in California that also match the filters currently applied.

How many clinical trials are recruiting in California?

17 of the 33 studies on this page are recruiting new participants as of the 12 Oct 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 13 are active but closed to new participants, and 3 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (California), 33 studies
PhaseStudiesRecruitingShare
Observational12836.4%
Phase 18324.2%
Phase 1/25415.2%
Phase 2319.1%
Phase 3309.1%
Not applicable216.1%

Most active sponsors

Lead sponsors with the most studies (California)
Lead sponsorStudiesRecruiting
GRAIL, Inc.31
AbbVie10
Actuate Therapeutics Inc.10
Alterome Therapeutics, Inc.10
Angiex, Inc.11
AstraZeneca10
Bayer10
Bristol-Myers Squibb11
Certis Oncology Solutions, Inc10
Conjupro Biotherapeutics, Inc.11
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.