TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

NCT06207032 · tracked via the Priya Life Science USA tracker

Sponsor

Tempus AI

Phase

Observational

Started

2024-06-26

Last updated

2026-02-24

Condition(s) studied

Cancer

Study summary

This study is a non-interventional, multicenter, multicohort evaluation of participants with cancer who will undergo longitudinal plasma ctDNA biomarker profiling at specific time points in addition to standard of care therapy.

Eligibility

Sex

ALL

Min age

18 Years

Max age

99 Years

Healthy volunteers

Inclusion Criteria: 1. ≥18 years of age 2. Willing to participate in the research 3. Able to provide informed consent 4. Must be diagnosed with cancer Exclusion Criteria: 1\. Not willing or able to have additional blood samples collected

Primary outcome measure(s)

Changes in ctDNA from baseline, on-treatment and post-treatment blood samples. — 5 years
Assess ctDNA kinetics using ctDNA clearance factors such as time to clearance, best overall clearance rate, best confirmed clearance, and time to ctDNA recurrence and correlate with standard of care therapy real-world outcomes such as overall survival, progression-free survival, time to next treatment, and time to treatment discontinuation.

Trial sites (32)

Facility	City	Region	Status
Alabama Oncology	Birmingham	Alabama	Recruiting
PIH Health Whittier Hospital & PIH Health Physicians	Whittier	California	Recruiting
Eastern CT and Hematology and Oncology Associates	Norwich	Connecticut	Recruiting
Cancer Specialists of North Florida	Jacksonville	Florida	Recruiting
Morehouse	Atlanta	Georgia	Recruiting
Piedmont Healthcare	Atlanta	Georgia	Recruiting
Southern Illinois Healthcare	Carterville	Illinois	Recruiting
Hope and Healing Cancer Services	Hinsdale	Illinois	Recruiting
Cancer Care Specialists of Illinois	O'Fallon	Illinois	Recruiting
Illinois Cancer Care	Peoria	Illinois	Recruiting
Northwest Oncology and Hematology	Rolling Meadows	Illinois	Terminated
Fort Wayne	Fort Wayne	Indiana	Terminated
Goshen Center for Cancer Care	Goshen	Indiana	Recruiting
St. Claire Healthcare	Morehead	Kentucky	Terminated
Frederick Health Regional System	Frederick	Maryland	Recruiting
Southcoast Centers for Cancer Care	Fairhaven	Massachusetts	Recruiting
Hannibal Regional Healthcare System, Inc.	Hannibal	Missouri	Recruiting
Lake Regional Health	Osage Beach	Missouri	Recruiting
Mosaic Life Care	Saint Joseph	Missouri	Active Not Recruiting
Oncology Hematology Associates	Springfield	Missouri	Recruiting
Hope Cancer Care of Nevada	Las Vegas	Nevada	Terminated
Cancer Care Specialists - Reno	Reno	Nevada	Recruiting
New Jersey Cancer Center	Belleville	New Jersey	Terminated
Regional Cancer Care Associates	Belleville	New Jersey	Terminated
Hematology Oncology Associates of Central NY	East Syracuse	New York	Recruiting
Cayuga Medical Center	Ithaca	New York	Recruiting
Sanford Roger Maris Cancer Center (Fargo)	Fargo	North Dakota	Recruiting
Aultman Medical Group	Canton	Ohio	Recruiting
Taylor Cancer Research Center	Maumee	Ohio	Recruiting
Cancer Care Associates of York	York	Pennsylvania	Recruiting
Cancer Care Northwest	Spokane	Washington	Recruiting
Pan American Center for Oncology Trials	Rio Piedras	Puerto Rico	Recruiting

More Tempus AI trials in the USA

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies Recruiting

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies Recruiting

Tempus Small Cell Lung Cancer Observational Study (Sculptor) Recruiting

Tempus Open Link for Individual Voices in Innovative Analytics Registry: Platform Protocol for Multimodal Real-World Evidence in Cancer Recruiting

GEMINI-NSCLC: NSCLC Biomarker Study Recruiting

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A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06207032 on ClinicalTrials.gov ↗ ← All trials in the USA