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Trackers› Clinical trials› Illinois
Clinical trial register · United States · industry-sponsored

Clinical Trials in Illinois, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9119 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 25 Sep 2026, 03:16 UTC
9119
Studies in scope
industry-sponsored, all four open statuses
4952
Recruiting now
open to new participants
2205
Lead sponsors
across recruiting studies
Top states
California 5301 Florida 4401 Illinois 2480 Georgia 2350 Arizona 2233
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca110 AbbVie101 Eli Lilly and Company71 Merck Sharp & Dohme LLC63 Novartis Pharmaceuticals60
State
California5301 Florida4401 Illinois2480 Georgia2350 Arizona2233
All 51 states
Target enrolment
to

Trials with a site in Illinois

2480 of 9119 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
REDUCED 1 - Renal Denervation Using Ultrasonic Catheter EmitteD Energy Study /
NCT05372679Uncontrolled Stage 2 Hypertension
SoniVie Inc.
Not applicable
25
Alabama, Arkansas, Connecticut, Illinois, Minnesota, New York, North Carolina, South Carolina
2022-11-11
Active, closed
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
NCT05583227Eosinophilic Esophagitis
DrugTezepelumab
AstraZeneca
Phase 3
368
Arizona, Arkansas, California, Colorado, Florida, Illinois, Iowa, Kansas
2022-11-10
Active, closed
A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)
NCT05490446Myelodysplastic Syndromes
DrugTebapivat
Agios Pharmaceuticals, Inc.
Phase 2
87
California, Connecticut, Florida, Illinois, Missouri, New York, North Carolina
2022-11-07
Active, closed
LAMBDA 002 (Lung Registry) Study
NCT05170425Lung Transplant Rejection
Natera, Inc.
Observational
154
California, Illinois, Maryland, Michigan, Missouri, New York, Ohio, Texas
2022-11-04
Active, closed
An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome
NCT05367960Fragile X Syndrome
Tetra Discovery Partners
Phase 3
314
California, Colorado, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2022-11-01
Active, closed
Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type
NCT05397639Agitation, Alzheimer's Type Dementia
Suven Life Sciences Limited
Phase 3
375
California, Connecticut, Florida, Illinois, New Jersey, New York, Ohio, South Carolina
2022-11-01
Recruiting
Study Evaluating UCART20x22 in B-Cell Non-Hodgkin Lymphoma
NCT05607420B-cell Non-Hodgkin Lymphoma (B-NHL)
DrugAlemtuzumab
Cellectis S.A.
Phase 1/2
80
Illinois, Massachusetts, New Jersey, Texas
2022-11-01
Active, closed
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
NCT05567796Obesity
DrugsCagrilintide·Semaglutide
Novo Nordisk A/S
Phase 3
3,400
Alabama, California, Colorado, Florida, Georgia, Hawaii, Illinois, Indiana
2022-11-01
Recruiting
Phase 2 Study for the Patient, Who Has Diagnosed With Small Cell Lung Cancer (SCLC) or Non Small Cell Lung Cancer (NSCLC) or Renal Cell Carcinoma (RCC) and Finished the First Line Stand Treatment , Need More Treatment
NCT05363280Small Cell Lung Cancer, Renal Cell Carcinoma (RCC), Non-Small Cell Lung
DrugAL8326
Advenchen Pharmaceuticals, LLC.
Phase 2
80
Alabama, Florida, Illinois, Missouri, Ohio
2022-11-01
Active, closed
A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
NCT05585320Advanced Solid Tumor, Pancreatic Adenocarcinoma, Malignant Melanoma (Cutaneous), Non-small Cell Lung Cancer (NSCLC)
DrugsModified FOLFIRINOX·Dabrafenib·Pembrolizumab
Immuneering Corporation
Phase 1/2
209
Arizona, California, Colorado, Florida, Illinois, Massachusetts, Minnesota, New York
2022-10-31
Active, closed
A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH
NCT05389449Paroxysmal Nocturnal Hemoglobinuria
DrugDanicopan
Alexion Pharmaceuticals, Inc.
Phase 3
80
California, Illinois, Maryland, Missouri, New York, Ohio, Texas
2022-10-28
Active, closed
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
NCT05169515Non-Hodgkin Lymphoma
DrugsIberdomide·Golcadomide·Mosunetuzumab·Glofitamab
Hoffmann-La Roche
Phase 1
121
California, Colorado, Florida, Illinois, North Carolina, Texas
2022-10-26
Active, closed
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
NCT05284747Cardiovascular Disease, Myocardial Infarction, Stroke, Coronary Revascularization
DrugEvolocumab
Amgen
Phase 4
6,019
Alabama, Arizona, California, Colorado, Connecticut, Florida, Idaho, Illinois
2022-10-26
Recruiting
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
NCT05552222Multiple Myeloma
DrugsTalquetamab·Teclistamab·Daratumumab·Lenalidomide
Janssen Research & Development, LLC
Phase 3
1,590
Arizona, California, Connecticut, Delaware, Florida, Georgia, Illinois, Iowa
2022-10-25
Active, closed
The GOREยฎ VIABAHNยฎ FORTEGRA Venous Stent IVC Study
NCT05409976Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates
Not applicable
136
California, District of Columbia, Illinois, Michigan, New York, North Carolina, Virginia
2022-10-25
Active, closed
A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension
NCT05203510Pulmonary Arterial Hypertension
DrugTreprostinil
United Therapeutics
Phase 4
52
Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana, Massachusetts
2022-10-20
Active, closed
A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis
NCT05559359Atopic Dermatitis, Eczema
DrugLebrikizumab
Eli Lilly and Company
Phase 3
377
Alabama, Arizona, Arkansas, California, Connecticut, Florida, Idaho, Illinois
2022-10-18
Active, closed
Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) Deficiency
NCT05345171OTC Deficiency
Ultragenyx Pharmaceutical Inc
Phase 3
37
California, Colorado, Illinois, Ohio
2022-10-18
Active, closed
A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment
NCT05455320Multiple Myeloma
DrugsTalquetamab·Pomalidomide·Daratumumab·Dexamethasone
Janssen Research & Development, LLC
Phase 3
864
Arizona, Arkansas, Connecticut, District of Columbia, Florida, Illinois, Kansas, Louisiana
2022-10-13
Recruiting
International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder
NCT05590715Autism Spectrum Disorder
Stalicla SA
Observational
1,500
Arizona, California, Florida, Illinois, Missouri, New Mexico, Texas, Utah
2022-10-13
Recruiting
M-Vizionโ„ข Macroscopic Radiographic Study
NCT05721859Revision Hip Arthroplasty
Medacta USA
Observational
70
Illinois, Massachusetts, New Hampshire, North Carolina, Pennsylvania, Utah
2022-10-12
Active, closed
Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer
NCT05502237Non-small Cell Lung Cancer
DrugsDomvanalimab·Zimberelimab·Nab-paclitaxel·Pemetrexed
Gilead Sciences
Phase 3
1,021
California, District of Columbia, Florida, Illinois, North Carolina, Ohio, Oregon, Pennsylvania
2022-10-12
Active, closed
A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors
NCT05537740Advanced Solid Tumors
DrugPembrolizumab
Bayer
Phase 1
129
Illinois, North Carolina, Texas, Utah
2022-10-11
Active, closed
A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815
NCT05557045Advanced Cancer, Metastatic Cancer, Solid Tumor, Melanoma
Jazz Pharmaceuticals
Phase 1
98
California, Colorado, Florida, Illinois, New York, Oklahoma, Pennsylvania, Tennessee
2022-10-10
Active, closed
Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies
NCT05397496B-cell Non-Hodgkin Lymphoma (B-NHL), B-cell Acute Lymphoblastic Leukemia (B-ALL)
DrugPIT565
Novartis Pharmaceuticals
Phase 1
61
Florida, Illinois, Kansas, New York, Oregon
2022-10-03
Active, closed
Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)
NCT05509023Atopic Dermatitis
DrugBempikibart
Q32 Bio Inc.
Phase 2
102
Alabama, California, Florida, Georgia, Idaho, Illinois, Indiana, Maryland
2022-09-30
Recruiting
Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief
NCT05432479Infantile Colic
The Archer-Daniels-Midland Company
Not applicable
80
Illinois
2022-09-30
Recruiting
A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies
NCT05443126NSCLC
DrugPemetrexed
Ellipses Pharma
Phase 1/2
265
California, District of Columbia, Florida, Illinois, Kentucky, Massachusetts, Michigan, New York
2022-09-30
Active, closed
Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRฮฑ) Expressing, Platinum-sensitive Epithelial Ovarian Cancer
NCT05456685High Grade Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer
DrugsMirvetuximab Soravtansine·Carboplatin
AbbVie
Phase 2
125
Arizona, California, Connecticut, Florida, Georgia, Illinois, Louisiana, Massachusetts
2022-09-28
Recruiting
Post-Market Study to Assess iTind Safety in Comparison to UroLift
NCT04757116Benign Prostatic Hyperplasia (BPH)
Olympus Corporation of the Americas
Not applicable
256
Arizona, California, Illinois, Louisiana, Minnesota, Nebraska, Nevada, New York
2022-09-26
Recruiting
A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
NCT05431088Sickle Cell Disease
Pfizer
Phase 2/3
389
Alabama, Connecticut, Florida, Georgia, Illinois, Louisiana, Michigan, Mississippi
2022-09-22
Active, closed
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
NCT05409066Follicular Lymphoma (FL)
DrugsEpcoritamab·Lenalidomide·Rituximab
Genmab
Phase 3
549
Arizona, Arkansas, California, Georgia, Hawaii, Illinois, Indiana, Louisiana
2022-09-20
Active, closed
Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePortยฎ Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOTโ„ข_CA)
NCT05574361Liver Transplantation
Organ Recovery Systems, Inc.
Not applicable
385
Illinois, New Jersey, Ohio, Utah
2022-09-19
Recruiting
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
NCT05519449Prostate Cancer, Metastatic Castration-resistant Prostate Cancer, Castration Resistant Prostatic Cancer
Janux Therapeutics
Phase 1
272
Alabama, Arizona, California, Connecticut, Florida, Illinois, Maryland, Minnesota
2022-09-15
Active, closed
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
NCT05531565Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus
DrugLitifilimab
Biogen
Phase 2/3
450
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2022-09-13
Active, closed
Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer
NCT05425940Colorectal Cancer
DrugsZanzalintinib·Regorafenib·Atezolizumab
Exelixis
Phase 3
901
Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana
2022-09-07
By invitation
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease
NCT04905693Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Progressive Pulmonary Fibrosis
DrugTreprostinil
United Therapeutics
Phase 3
1,850
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2022-09-06
Recruiting
TVMR With the INNOVALVE System Trial - Early Feasibility Study
NCT04919980Mitral Valve Regurgitation (Degenerative or Functional)
Edwards Lifesciences
Not applicable
85
California, Florida, Georgia, Illinois, Michigan, Minnesota, Missouri, New Jersey
2022-09-01
Recruiting
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
NCT05533697Advanced Solid Tumors
DrugsIpilimumab·Nivolumab·Pembrolizumab
ModernaTX, Inc.
Phase 1/2
361
California, Colorado, District of Columbia, Florida, Illinois, Massachusetts, Michigan, Missouri
2022-09-01
Recruiting
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
NCT05386108Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms
DrugsElacestrant·Abemaciclib
Stemline Therapeutics, Inc.
Phase 1/2
73
California, Illinois, Massachusetts, Michigan, Ohio, Oregon, Tennessee, Texas
2022-08-31
Active, closed
Safety, Tolerability and PK of Subcutaneous D-4517.2 in Subjects With Wet AMD or DME
NCT05387837Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Ashvattha Therapeutics, Inc.
Phase 2
50
California, Illinois, Indiana, Maryland, Massachusetts, Missouri, New Jersey, Pennsylvania
2022-08-31
Recruiting
Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
NCT05394103Advanced Cancer, Metastatic Cancer
DrugPembrolizumab
Qurient Co., Ltd.
Phase 1/2
130
Arizona, California, Florida, Illinois, Minnesota, New Jersey, Texas
2022-08-30
Recruiting
Use of the REGENETENโ„ข Bioinductive Implant System in High Grade Partial-thickness Tears
NCT05444465Rotator Cuff Injuries
Smith & Nephew, Inc.
Not applicable
234
Georgia, Illinois, Maryland, Ohio, Pennsylvania, Texas, Wisconsin
2022-08-30
Recruiting
Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
NCT05455619HR+/HER2-negative Breast Cancer, Metastatic Breast Cancer
SynDevRx, Inc.
Phase 1/2
52
California, Florida, Illinois, Michigan, Ohio, Pennsylvania, Tennessee, Texas
2022-08-26
Active, closed
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)
NCT05500222NASH, Cirrhosis, Liver
DrugResmetirom
Madrigal Pharmaceuticals, Inc.
Phase 3
845
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Illinois
2022-08-26
Recruiting
A Prospective Sub-Study of the Global Hypophosphatasia Registry
NCT05234567Hypophosphatasia
DrugAsfotase alfa
Alexion Pharmaceuticals, Inc.
Observational
30
Connecticut, Illinois, Massachusetts, Missouri, New York, Ohio, Pennsylvania, Tennessee
2022-08-25
Recruiting
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
NCT05511363Psychosis Associated With Alzheimer's Disease
DrugKarXT
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
410
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, New York
2022-08-23
By invitation
Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis
NCT05374590Generalized Myasthenia Gravis, gMG
DrugsEfgartigimod PH20·Efgartigimod
argenx
Phase 2/3
12
Illinois, North Carolina, Virginia
2022-08-18
Active, closed
GammaTile and Stupp in Newly Diagnosed GBM
NCT05342883Glioblastoma
GT Medical Technologies, Inc.
Phase 4
61
Arizona, California, Florida, Georgia, Illinois, Indiana, Kansas, Michigan
2022-08-17
Active, closed
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen
NCT05502341HIV-1-infection
DrugsBIC/LEN FDC·Bictegravir·Lenacapavir
Gilead Sciences
Phase 2/3
689
California, Colorado, Connecticut, Florida, Georgia, Illinois, Missouri, New Jersey
2022-08-16
Active, closed
MiSight 1 Day Safety Post-Approval Study
NCT05285527Myopia
CooperVision, Inc.
Not applicable
2,400
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Illinois, Indiana
2022-08-15
Recruiting
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
NCT05377996Triple Negative Breast Cancer, Breast Cancer, Endometrial Cancer, Ovarian Cancer
Day One Biopharmaceuticals, Inc.
Phase 1/2
360
Arizona, California, Florida, Georgia, Illinois, Massachusetts, Michigan, Minnesota
2022-08-15
Recruiting
Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V
NCT05268289Lupus Nephritis
DrugIptacopan
Novartis Pharmaceuticals
Phase 2
240
Arizona, California, Colorado, Florida, Illinois, Kansas, Louisiana, Maryland
2022-08-10
Active, closed
A Study of Belzutifan (MK-6482) in Combination With Palbociclib Versus Belzutifan Monotherapy in Participants With Advanced Renal Cell Carcinoma (MK-6482-024/LITESPARK-024)
NCT05468697Renal Cell Carcinoma
DrugsBelzutifan·Palbociclib
Merck Sharp & Dohme LLC
Phase 1/2
60
District of Columbia, Illinois, Massachusetts, Utah
2022-08-10
Active, closed
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT
NCT04858776Iliofemoral; Thrombosis
Mercator MedSystems, Inc.
Phase 2
60
Connecticut, Florida, Illinois, Louisiana, Maryland, New York, North Carolina, Ohio
2022-08-08
Active, closed
Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome
NCT05349214Sjogren Syndrome
DrugIanalumab
Novartis Pharmaceuticals
Phase 3
506
California, Florida, Georgia, Illinois, Kansas, Massachusetts, New Mexico, New York
2022-08-04
Active, closed
A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)
NCT05306340Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
DrugsGiredestrant·Tamoxifen·Exemestane·Everolimus
Genentech, Inc.
Phase 3
373
Alaska, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois
2022-08-03
Active, closed
Evaluation of Rifaximin SSD for Delaying Encephalopathy Decompensation in Patients With Cirrhosis
NCT05297448Hepatic Encephalopathy
DrugRifaximin SSD
Bausch Health Americas, Inc.
Phase 3
466
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2022-08-03
Active, closed
First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors
NCT05489237Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumor (GIST), Digestive System Disease, Gastrointestinal Diseases
DrugIDRX-42
IDRX, Inc., a wholly owned subsidiary of GSK, LLC
Phase 1
276
Florida, Illinois, Massachusetts, Missouri, New York, Oregon, Pennsylvania, Texas
2022-08-03
Active, closed
A Study to Learn How Safe and Tolerable Vonsetamig is in Adult Patients With Chronic Kidney Disease (CKD) Who Need Kidney Transplantation and Are Highly Sensitized to Human Leukocyte Antigen (HLA)
NCT05092347Chronic Kidney Disease (CKD)
DrugVonsetamig
Regeneron Pharmaceuticals
Phase 1/2
43
California, Connecticut, District of Columbia, Illinois, Maryland, Minnesota, New York, Pennsylvania
2022-08-02
Recruiting
A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data
NCT06877884Cancer
N-Power Medicine
Observational
20,000
California, Delaware, Illinois, New Mexico, Pennsylvania, Texas
2022-08-01
Recruiting
A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM
NCT05303467Glioblastoma Multiforme, Recurrent Glioblastoma
Boston Scientific Corporation
Phase 1
36
Alabama, California, Florida, Illinois, Maryland, Missouri, New York, Texas
2022-07-30
Active, closed
Noninterventional Study Evaluating Parkinson's Disease Diary Use
NCT05363046Parkinson's Disease
BlueRock Therapeutics
Observational
194
Arizona, California, Colorado, Florida, Illinois, Kansas, Kentucky, Massachusetts
2022-07-29
Active, closed
Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF
NCT05389215Idiopathic Pulmonary Fibrosis
Daewoong Pharmaceutical Co. LTD.
Phase 2
102
Arizona, California, Illinois, Kansas, Massachusetts, Michigan, Missouri, North Carolina
2022-07-29
Active, closed
A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II)
NCT05371613Mucopolysaccharidosis II
DrugsIdursulfase·Tividenofusp alfa
Denali Therapeutics Inc.
Phase 2/3
65
California, Illinois, New Jersey, North Carolina, Ohio, Pennsylvania, Texas, Utah
2022-07-21
Active, closed
A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)
NCT05458297Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Follicular Lymphoma, Richter Transformation Lymphoma
DrugsZilovertamab vedotin·Nemtabrutinib
Merck Sharp & Dohme LLC
Phase 2
189
Alaska, Arizona, Colorado, Illinois, Kansas, Kentucky, Maryland, Massachusetts
2022-07-21
Active, closed
Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
NCT05382299Triple Negative Breast Cancer, PD-L1 Negative
DrugsSacituzumab Govitecan·Nab-paclitaxel·Gemcitabine·Carboplatin
Gilead Sciences
Phase 3
623
Arizona, California, Colorado, Florida, Georgia, Illinois, Iowa, Kentucky
2022-07-20
Active, closed
First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors
NCT05438329Advanced Solid Tumor
DrugsDB-1305/BNT325·Pumitamig
DualityBio Inc.
Phase 1/2
1,123
Arizona, California, District of Columbia, Florida, Hawaii, Illinois, Michigan, Nevada
2022-07-19
Recruiting
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
NCT06426628Pulmonary Nodule, Solitary, Lung Cancer
Veracyte, Inc.
Observational
2,400
Connecticut, Florida, Illinois, Kansas, Kentucky, Louisiana, Maryland, Massachusetts
2022-07-18
Active, closed
Study of Anitocabtagene-autoleucel in Relapsed or Refractory Multiple Myeloma (iMMagine-1)
NCT05396885Multiple Myeloma
DrugAnitocabtagene-autoleucel
Kite, A Gilead Company
Phase 2
136
Arizona, Arkansas, Colorado, Florida, Georgia, Illinois, Maryland, Massachusetts
2022-07-15
Recruiting
Tempus Small Cell Lung Cancer Observational Study (Sculptor)
NCT05257551Small Cell Lung Cancer
Tempus AI
Observational
200
California, Colorado, Illinois, Maryland, New Jersey, North Carolina, Ohio, Oklahoma
2022-07-13
By invitation
ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study
NCT05481827Age Related Macular Degeneration (AMD)
Gyroscope Therapeutics Limited
Phase 2
225
California, Colorado, Florida, Illinois, Indiana, Iowa, Maryland, Massachusetts
2022-07-12
Active, closed
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
NCT05360446Coronary Artery Disease
DrugInclisiran sodium
Novartis Pharmaceuticals
Phase 3
609
Alabama, Alaska, California, Connecticut, District of Columbia, Florida, Illinois, Indiana
2022-07-08
Active, closed
Roll-over Study to Allow Continued Access to Ribociclib
NCT05161195Metastatic Breast Cancer
DrugsGoserelin·Tamoxifen·Anastrozole·Ribociclib
Novartis Pharmaceuticals
Phase 4
134
Arizona, Arkansas, California, Colorado, Florida, Georgia, Illinois, Indiana
2022-07-07
Active, closed
A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy
NCT05337553Spinal Muscular Atrophy, Neuromuscular Diseases, SMA
DrugTaldefgrobep alfa
Biohaven Pharmaceuticals, Inc.
Phase 3
269
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa
2022-07-06
Active, closed
Expander-2 Trial: Randomized Study to Evaluate Safety & Efficacy of the Urocrossยฎ Expander System & Retrieval Sheath
NCT05400980Benign Prostatic Hyperplasia
Prodeon Medical, Inc
Not applicable
240
Illinois, Virginia
2022-07-05
Recruiting
Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery
NCT04918173Congenital Antithrombin Deficiency
Octapharma
Phase 3
38
District of Columbia, Florida, Illinois, New York, North Carolina
2022-07-01
Active, closed
Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis
NCT04991116Psoriatic Arthritis
Sun Pharmaceutical Industries Limited
Phase 3
529
Alabama, Arizona, California, Florida, Georgia, Illinois, Kansas, Missouri
2022-06-30
Recruiting
An Observational Study of Carbagluยฎ for the Treatment of MMA and PA in Adults and Pediatrics
NCT05040178Hyperammonemia, Methylmalonic Acidemia, Propionic Acidemia
DrugCarglumic Acid
RECORDATI GROUP
Observational
20
District of Columbia, Florida, Illinois, Indiana, New York
2022-06-30
Active, closed
Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer
NCT05257408Ovarian Neoplasm, Fallopian Tube Neoplasms, Peritoneal Neoplasms
DrugsNab-paclitaxel /m^2·Relacorilant
Corcept Therapeutics
Phase 3
381
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2022-06-29
Active, closed
(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis
NCT05186753SSM, Mastocytosis, Indolent, Mastocytosis, Systemic, Mastocytosis
DrugBezuclastinib
Cogent Biosciences, Inc.
Phase 2
237
Alabama, Arizona, California, Florida, Georgia, Illinois, Maryland, Massachusetts
2022-06-27
Active, closed
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
NCT05285553Myopia
CooperVision, Inc.
Not applicable
900
Alabama, California, Florida, Illinois, Indiana, Kansas, Massachusetts, Minnesota
2022-06-25
Recruiting
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
NCT05417594Advanced Solid Malignancies
DrugsPalacaparib·Datopotamab deruxtecan·Dato-DXd·Temozolomide
AstraZeneca
Phase 1/2
695
California, Illinois, Massachusetts, New York, Oregon, Texas, Virginia
2022-06-24
Active, closed
Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
NCT04975997Multiple Myeloma
DrugsIberdomide·Bortezomib·Daratumumab·Dexamethasone
Celgene
Phase 3
939
Arkansas, California, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky
2022-06-23
Active, closed
A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
NCT05126758Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases
DrugDeramiocel
Capricor Inc.
Phase 3
106
Arizona, Arkansas, California, Colorado, Georgia, Illinois, Iowa, Massachusetts
2022-06-22
Recruiting
GEMINI-NSCLC: NSCLC Biomarker Study
NCT05236114Non-Small Cell Lung Cancer
Tempus AI
Observational
1,200
Alabama, Arkansas, California, Connecticut, Florida, Georgia, Hawaii, Illinois
2022-06-22
Active, closed
Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age
NCT05422222Cystic Fibrosis
DrugVX-121/TEZ/D-IVA
Vertex Pharmaceuticals Incorporated
Phase 3
210
California, Colorado, Georgia, Illinois, Indiana, Massachusetts, Minnesota, Missouri
2022-06-21
Active, closed
Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
NCT05316701Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Mixed Phenotype Acute Leukemia, Undifferentiated Leukemia
DrugOrca-T
Orca Biosystems, Inc.
Phase 3
187
California, Colorado, Florida, Georgia, Illinois, Massachusetts, Michigan, New York
2022-06-21
Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
NCT05172960Aortic Stenosis, Severe
Edwards Lifesciences
Not applicable
1,234
California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Kansas
2022-06-20
Active, closed
Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria
NCT05270837Phenylketonuria (PKU)
DrugPegvaliase
BioMarin Pharmaceutical
Phase 3
55
Arizona, Arkansas, Colorado, Florida, Illinois, Indiana, Kentucky, Massachusetts
2022-06-17
Recruiting
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
NCT05135091Mesial Temporal Lobe Epilepsy
DrugNRTX-1001
Neurona Therapeutics
Phase 3
88
Alabama, Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Illinois
2022-06-16
Active, closed
A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting
NCT05348733Chronic Kidney Disease, Type 2 Diabetes Mellitus
Bayer
Observational
4,613
Alabama, Arizona, Arkansas, California, Florida, Georgia, Hawaii, Illinois
2022-06-13
Recruiting
Study of XmAbยฎ819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma
NCT05433142Clear Cell Renal Cell Carcinoma
Xencor, Inc.
Phase 1
307
Arizona, California, Connecticut, Florida, Georgia, Illinois, Kentucky, Minnesota
2022-06-13
Active, closed
Non-interventional Study on Osilodrostat in Patients With Endogenous Cushing's Syndrome
NCT05382156Endogenous Cushing's Syndrome
DrugOsilodrostat
RECORDATI GROUP
Observational
206
Arizona, Georgia, Illinois, Indiana, Kentucky, Massachusetts, Michigan, Minnesota
2022-06-13
Active, closed
MOTIV BTK Randomized Controlled Trial
NCT05406622Critical Limb Ischemia
REVA Medical, Inc.
Not applicable
292
California, Colorado, Connecticut, Florida, Georgia, Hawaii, Illinois, Iowa
2022-06-10
Active, closed
ProVee Urethral Expander System IDE Study (ProVIDE)
NCT05186740BPH With Symptomatic Lower Urinary Tract Symptoms
ProVerum Medical
Not applicable
221
California, Florida, Illinois, Nevada, New York, North Carolina, Texas, Virginia
2022-06-09
Recruiting
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
NCT05245500Mesothelioma, Non Small Cell Lung Cancer, Malignant Peripheral Nerve Sheath Tumors, Solid Tumor
DrugBMS-986504
Bristol-Myers Squibb
Phase 1
336
Arizona, Colorado, Florida, Illinois, Massachusetts, Michigan, Minnesota, New Jersey
2022-06-09
Recruiting
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
NCT05384626Locally Advanced Solid Tumor, Metastatic Solid Tumor
DrugsNeladalkib·Repaglinide·Itraconazole·Midazolam
Nuvalent Inc.
Phase 1/2
840
California, Colorado, District of Columbia, Florida, Georgia, Illinois, Maryland, Massachusetts
2022-06-09
Recruiting
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
NCT05365581Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma
DrugsASP2138·Ramucirumab·Leucovorin·Irinotecan
Astellas Pharma Global Development, Inc.
Phase 1
398
California, Illinois, Kansas, New Jersey, New York, North Carolina, Texas, Washington
2022-06-07
Active, closed
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period
NCT05175105Pediatric Pyruvate Kinase Deficiency, Pediatric Hemolytic Anemia
DrugMitapivat
Agios Pharmaceuticals, Inc.
Phase 3
30
California, Colorado, Georgia, Illinois, Massachusetts, Michigan, North Carolina, Pennsylvania
2022-06-06
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 25 September 2026. https://priyalifescience.com/clinical-trials-usa/state/illinois?page=18

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,119 studies in total at the last sync on 25 Sep 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 2,480 of those studies with a site in Illinois.

How many clinical trials are recruiting in Illinois?

1,263 of the 2,480 studies on this page are recruiting new participants as of the 25 Sep 2026, 03:16 UTC sync. A further 37 have not yet opened recruitment, 1,117 are active but closed to new participants, and 63 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.