Real-time Motion Management During Prostate and Lung Radiotherapy
Condition(s) studied
Investigational drug(s) / intervention(s)
Triggered imaging on TrueBeam with margin reduction: At interim analysis the Planning target volume (PTV) will be reduced based on the accuracy of the TrueBeam triggered imaging motion management technique.
Synchrony MLC tracking on fiducials with margin reduction: At interim analysis the Planning target volume (PTV) will be reduced based on the accuracy of the Radixact Synchrony motion management technique.
Synchrony MLC tracking and lung adaptive model with margin reduction: At interim analysis the Planning target volume (PTV) will be reduced based on the accuracy of the Radixact Synchrony motion management technique for lung cancer.
Study summary
The goal of this interventional non-inferiority trial is to assess the accuracy of different real-time motion management radiotherapy techniques. The main question the study aims to answer are:
* What are the target margins for radiotherapy with motion management that are not inferior to target margin without motion management
* What are the dosimetric and geometrical accuracy to patient for the motion management techniques.
Participants will answer QoL questionary, and the accuracy of treatment will be assessed from treatment data.
Eligibility
Primary outcome measure(s)
- Dosemetric accuracy — At treatment completion, approximately 1-4 weeks
Dose coverage defined as dose to 99% of clinical target volume (CTV) (D99%) to target including margin for other uncertainties.
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Skåne University Hospital | Lund | Skåne County |
More Region Skane trials in Sweden
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05844761 on ClinicalTrials.gov ↗ ← All trials in Sweden