Study With Various Immunotherapy Treatments in Participants With Lung Cancer
Condition(s) studied
Investigational drug(s) / intervention(s)
Domvanalimab: Administered as specified in the treatment arm
Quemliclustat: Administered as specified in the treatment arm
Zimberelimab: Administered as specified in the treatment arm
Docetaxel: Administered as specified in the treatment arm
Platinum-Based Doublet: Administered as specified in the treatment arm
Study summary
The purpose of this study is to assess the objective response rate (ORR) of immunotherapy-based combination therapy and to assess the safety and tolerability of immunotherapy-based combination therapy.
Eligibility
Primary outcome measure(s)
- Objective response rate (ORR) as measured by Response Evaluation Criteria in Solid Tumors (RECIST v1.1) — Up to 58 months
- The incidence and severity of adverse events (AEs) and serious adverse events (SAEs) — Up to 58 months
Trial sites (53)
| Facility | City | Region | Status |
|---|---|---|---|
| University of Alabama at Birmingham (UAB) | Birmingham | Alabama | |
| University of California San Diego (UCSD) | La Jolla | California | |
| Memorial Cancer Institute at Memorial Regional Hospital | Hollywood | Florida | |
| Hematology Oncology Associates Of The Treasure Coast | Port Saint Lucie | Florida | |
| Florida Cancer Specialists (Administration and Drug Shipment) | The Villages | Florida | |
| Northwestern Memorial Hospital | Chicago | Illinois | |
| Ochsner Clinic Foundation | Jefferson | Louisiana | |
| Henry Ford Hospital | Detroit | Michigan | |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | |
| Medical Oncology Associated, PS (dba Summit Cancer Centers) | Spokane | Washington | |
| The Border Cancer Hospital | Albury | New South Wales | |
| Pindara Private Hospital | Benowa | Queensland | |
| Cancer Research SA Pty Ltd | Adelaide | South Australia | |
| Sir Charles Gairdner Hospital | Nedlands | Western Australia | |
| CHU Bordeaux Centre Francois Magendie Hôpital du Haut Lévèque | Bordeaux | France | |
| Hospices Civils de Lyon Centre Hospitalier Lyon Sud | Lyon | France | |
| Institut De Cancerologie Strasbourg Europe ICANS | Strasboug | France | |
| Hopital FOCH | Suresnes | France | |
| LTD High Technology Hospital Medcenter | Batumi | Georgia | |
| Caucasus Medical Center | Tbilisi | Georgia | |
| Israel Georgian Medical Research Clinic Healthycore | Tbilisi | Georgia | |
| JSC K. Eristavi National Center of Experimental and Clinical Surgery | Tbilisi | Georgia | |
| Ltd Pineo Medical Ecosystem | Tbilisi | Georgia | |
| Istituto Romagnolo per lo Studio dei Tumori-Dino Amadori - IRST | Meldola | Italy | |
| stituto Nazionale per lo Studio e la Cura dei Tumori | Milan | Italy | |
| Istituto Oncologico Veneto IRCCS | Padova | Italy | |
| Azienda Sanitaria Territoriale Pesaro Urbino (AST PU) | Pesaro | Italy | |
| Fondazione IRCCS Istituto Nazionale dei tumori di Milano | Rome | Italy | |
| Szpitale Pomorskie sp. z o.o | Gdynia | Poland | |
| Uniwersyteckie Centrum Kliniczne, im. prof. K. Gibińskiego | Katowice | Poland | |
| Medpolonia Sp. Z.o.o. | Poznan | Poland | |
| Centrum Onkologii - Instytut im. Marii Sk?odowskiej-Curie | Warsaw | Poland | |
| Samsung Changwon Hospital | Changwon-Si | South Korea | |
| Chungbuk National University Hospital | Cheongju-si | South Korea | |
| Chonam National University Hwasun Hospital | Hwasun-gun | South Korea | |
| Korea University Guro Hospital | Seoul | South Korea | |
| Asan Medical Center | Seoul | South Korea | |
| Hospital de la Santa Creu i Sant Pau | Barcelona | Spain | |
| Hospital Universitari Mutua Terrassa | Barcelona | Spain | |
| UOMI Cancer Centre | Barcelona | Spain |
+ 13 more sites — see the full list on the official registry below.
More Gilead Sciences trials in Italy
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05676931 on ClinicalTrials.gov ↗ ← All trials in Italy