Neurofeedback Training of Anterior Insula Activity Based on Unidimensional vs. Multidimensional Interoceptive Regulation Strategies

Condition(s) studied

Investigational drug(s) / intervention(s)

real-time fMRI neurofeedback training: Real-time neurofeedback information is computed using the Turbo Brain voyager (TBV) 4.0 software (Brain Innovation, Maastricht, The Netherlands). Functional images are collected and processed in real time based on contrasts of regulation vs. rest conditions. The blood oxygen level dependent (BOLD) signal of the target region is then transformed into visual bars and displayed to participants via the projector screen. Both groups will undergo the same paradigm, but with different interoception strategies.

Study summary

The purpose of this study is to compare the neural and behavioral effects of real-time functional magnetic resonance imaging (fMRI) neurofeedback training using two different interoceptive strategies: a unidimensional heartbeat detection strategy and a multidimensional interoception strategy. Specifically, the study compares the efficacy of these two regulation strategies in regulating activity of the anterior insula, a key brain region involved in interoceptive and emotional processing.

Eligibility

Primary outcome measure(s)

• Neural activity of the anterior insula based on blood oxygen level-dependent (BOLD) signal — 1 hour
  The anterior insula activity induced during the regulation block compared to the baseline block.

Trial sites (1)

More University of Electronic Science and Technology of China trials in China

Other trials for the same condition