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Clinical Trials in China / NCT07416370
Enrolling by invitation Not applicable

Neurofeedback Training of Anterior Insula Activity Based on Unidimensional vs. Multidimensional Interoceptive Regulation Strategies

NCT07416370 · tracked via the Priya Life Science China tracker
Sponsor
University of Electronic Science and Technology of China
Phase
Not applicable
Started
2026-02-02
Last updated
2026-02-18

Condition(s) studied

Healthy

Investigational drug(s) / intervention(s)

real-time fMRI neurofeedback training

real-time fMRI neurofeedback training: Real-time neurofeedback information is computed using the Turbo Brain voyager (TBV) 4.0 software (Brain Innovation, Maastricht, The Netherlands). Functional images are collected and processed in real time based on contrasts of regulation vs. rest conditions. The blood oxygen level dependent (BOLD) signal of the target region is then transformed into visual bars and displayed to participants via the projector screen. Both groups will undergo the same paradigm, but with different interoception strategies.

Study summary

The purpose of this study is to compare the neural and behavioral effects of real-time functional magnetic resonance imaging (fMRI) neurofeedback training using two different interoceptive strategies: a unidimensional heartbeat detection strategy and a multidimensional interoception strategy. Specifically, the study compares the efficacy of these two regulation strategies in regulating activity of the anterior insula, a key brain region involved in interoceptive and emotional processing.

Eligibility

Sex
ALL
Min age
18 Years
Max age
30 Years
Healthy volunteers
Accepted
Inclusion Criteria: * No past or current psychiatric or neurological or other main disorders. Exclusion Criteria: * Current use of medications. * History of brain injury Medical or mental illness * Contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning).

Primary outcome measure(s)

  • Neural activity of the anterior insula based on blood oxygen level-dependent (BOLD) signal — 1 hour
    The anterior insula activity induced during the regulation block compared to the baseline block.

Trial sites (1)

FacilityCityRegionStatus
University of Electronic Science and Technology of China Chengdu Sichuan

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07416370 on ClinicalTrials.gov ↗ ← All trials in China