Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline

Condition(s) studied

Investigational drug(s) / intervention(s)

multi-modal targeted intervention (e.g., cognitive training, exercise, games): The Intervention group will be given recommended interventions tailored to individuals based on their risks (e.g., physical exercise programs, cognitive training, dietary advice, control of blood pressure and cholesterol, healthy diet, control obesity, stop smoking,reduce alcohol excess)

Study summary

This study investigates the neural mechanisms of cognitive function decline, cognitive assessment methods for subjects with mild cognitive dysfunction (Mild cognitive impairment, MCI, or cognitive decline milder than MCI), and the approaches used to improve and restore cognitive function.

Eligibility

Primary outcome measure(s)

• Change in Cognitive function (SCD-9) — Change from Baseline Cognitive test results at 3 months.
  The SCD-9 questionnaire is used to assess cognitive function of participants.
• Change in Cognitive function (MoCA) — Change from Baseline Cognitive test results at 3 months.
  The Montreal Cognitive Assessment test is used to assess cognitive function of participants.
• Change in Cognitive function (AD8) — Change from Baseline Cognitive test results at 3 months.
  The AD8 test is used to assess cognitive function of participants.
• Change in Cognitive function (CDR) — Change from Baseline Cognitive test results at 3 months.
  The Clinical Dementia Rating (CDR) test is used to assess cognitive function of participants.

Trial sites (1)

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