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Clinical Trials in China / NCT05981677
Recruiting Observational

Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents

NCT05981677 · tracked via the Priya Life Science China tracker
Sponsor
University of Electronic Science and Technology of China
Phase
Observational
Started
2023-12-06
Last updated
2024-04-11

Condition(s) studied

Nonsuicidal Self InjuryRisk-Taking

Study summary

Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this maladaptive behavior, especially for adolescents. Accumulating evidence suggests that decision processes and risk-taking are strongly influenced by the affective state of the individual. However, whether these interactions are disrupted in NSSI adolescents has not been systematically examined. In the current study, the investigators modified one of the most widely used paradigms for measuring an individual's risk decision-making, the Balloon Analogue Risk Task (BART). The investigators combine social reward (green balloon), punishment (red balloon), and control feedback (yellow balloon), to investigate whether the NSSI adolescents have dysfunctional risk-taking behavior while facing different social outcomes. The investigators recruit one group of NSSI adolescents (n = 40) and one health control (HC) group (n = 40), to compare their risk-related decisions during the emotional BART. The investigators hypothesize that compared to HC, NSSI adolescents will show altered effects of social reward and punishment on risk-related decision-making, in particular higher risk avoidance in the context of social punishment.

Eligibility

Sex
ALL
Min age
15 Years
Max age
18 Years
Healthy volunteers
Accepted
Inclusion Criteria: * 15-18 years * right-handed * normal or corrected normal visual acuity * meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year) Exclusion Criteria: * diagnosis of borderline personality disorder, major depressive disorder, other * psychiatric disorders, etc. * high suicidal risk * recent use of medications that can affect neural activity * have received or are receiving Dialectical Behavior Therapy (DBT) other treatment for emotional problems within the past 6 months * have a contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning)

Primary outcome measure(s)

  • Risky avoidance measured by BART — About 20 minutes
    Adjusted number of pumps (average number of pumps excluding balloons that exploded) as the index of risk avoidance. Alterations in the patients will be determined by using ANOVA models with the group (NSSI vs. HC) as a between-subject factor and emotional feedback (social reward, social punishment, and control) as a within-subject factor.
  • Decision-making measured by BART — About 20 minutes
    Earned money (total amount of money earned in the task) as the index of decision-making. Alterations in the patients will be determined by using ANOVA models with the group (NSSI vs. HC) as a between-subject factor and emotional feedback (social reward, social punishment, and control) as a within-subject factor.

Trial sites (1)

FacilityCityRegionStatus
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu Sichuan Recruiting

More University of Electronic Science and Technology of China trials in China

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Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts Recruiting
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Other trials for the same condition

Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts Recruiting
Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents Recruiting
Altered Neural Pain Empathic Reactivity in NSSI Adolescents Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05981677 on ClinicalTrials.gov ↗ ← All trials in China