Electrical Impedance Tomography-Based Prognostic Model for ARDS

NCT06967207 · tracked via the Priya Life Science China tracker

Sponsor

XiaoJing Zou,MD

Phase

Observational

Started

2025-04-15

Last updated

2025-05-13

Condition(s) studied

Acute Respiratory Distress Syndrome (ARDS)Ventilator-induced Lung Injury

Investigational drug(s) / intervention(s)

Not applicable- observational study

Not applicable- observational study: Not applicable- observational study

Study summary

This multicenter, prospective, observational study aims to develop and validate an EIT-based prognostic model for ARDS. By focusing on the pathophysiological characteristics of ARDS and the causes of ventilator-induced lung injury, the investigators intend to establish a prognostic model that reveals lung injury and heterogeneity, enabling risk stratification and guiding individualized treatment.

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: 1. Meet the new 2023 ARDS global definition; 2. Age 18-80 years Exclusion Criteria: 1. Expected death within 24 hours of screening; 2. Metastatic cancer (active malignancy with distant metastases); 3. Severe psychiatric disorders; 4. Pregnancy or postpartum status; 5. Pneumothorax or moderate to large pleural effusion without adequate drainage; 6. Chronic respiratory failure; 7. Patients with pulmonary embolism or pulmonary hypertension; 8. Heart failure patients: EF \<50% or NYHA class III or IV; 9. Patient/family refusal to participate; 10. Participation in another interventional trial within 3 months prior to enrollment

Primary outcome measure(s)

28-day mortality rate — From date of study enrollment (Day 0) until Day 28

Trial sites (4)

Facility	City	Region	Status
Department of Critical Care Medicine, Guangdong Provincial People's Hospital	Guangzhou	Guangdong	Recruiting
Department of Critical Care Medicine, Renmin Hospital of Wuhan University	Wuhan	Hubei	Recruiting
Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China Department of	Wuhan	Hubei	Recruiting
Department of Emergency, Zhongshan Hospital, Fudan University	Shanghai	Shanghai Municipality	Recruiting

More XiaoJing Zou,MD trials in China

Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS Recruiting

Other trials for the same condition

Electrical Impedance Tomography-Guided Identification of the Optimal Lateral Position in Postoperative ARDS Recruiting

RSPO3/SDC-1 Pathway Dysfunction in Alveolar Repair After ARDS in Older Adults Starting soon

Mechanism Study of Ventilator-Induced Lung Injury in Elderly People. Recruiting

A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation Recruiting

The Feasibility of Pulmonary Perfusion Assessment Using Sodium Bicarbonate Contrast With Electrical Impedance Tomography: A Prospective Pilot Study Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06967207 on ClinicalTrials.gov ↗ ← All trials in China