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Trackers› Clinical trials› Heart Failure
Clinical trial register · Canada

Heart Failure Trials in Canada, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Canada and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6553 matching records held by the registry are in this view. Synced 10 Nov 2026, 03:20 UTC
6553
Studies in scope
all four open statuses
3487
Recruiting now
open to new participants
880
Lead sponsors
across recruiting studies
Top sites
Toronto 24 Montreal 15 Edmonton 13 Ottawa 12 Hamilton 11
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
University of Alberta4 Ottawa Heart Institute Research Corporation3 University Health Network, Toronto3 Colorado Prevention Center3 Novo Nordisk A/S3 Population Health Research Institute3 Boehringer Ingelheim2 University of Calgary2 The Hospital for Sick Children2 Cardiology Research UBC2 Alleviant Medical, Inc.2 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's2 Edwards Lifesciences2 NHS Greater Glasgow and Clyde1 Corvia Medical1 Dinesh Thavendiranathan1 Medtronic1 Cytokinetics1 Baylor College of Medicine1 Christine Henri1 Cardiac Dimensions, Inc.1 McGill University Health Centre/Research Institute of the McGill University Health Centre1 Merck Sharp & Dohme LLC1 Centre hospitalier de l'Université de Montréal (CHUM)1 V-Wave Ltd1 Abbott Medical Devices1 Pfizer1 AstraZeneca1 Samantha Anthony1 Subodh Verma1 Habib Khan1 Bruyère Health Research Institute.1 Institute for Clinical Evaluative Sciences1 Alessandro Doria1 Bristol-Myers Squibb1 Hamilton Health Sciences Corporation1
Site location
Toronto24 Montreal15 Edmonton13 Ottawa12 Hamilton11 Vancouver11 Calgary10 Québec6 Winnipeg6 Cambridge5 London5 Halifax5 Newmarket5 Greater Sudbury4 Surrey4 Victoria4 Mississauga3 North York3 Sherbrooke3 Kingston3 Winchester3 Kitchener2 Oakville2 Oshawa2 Peterborough2 North Vancouver2 Sarnia2 Moncton2 Scarborough Village1 Waterloo1 Kelowna1 Thunder Bay1 Richmond1 Chicoutimi1 Sherwood Park1 Abbotsford British Columbia1 Saint John1 St. John's1 Sydney1 Burlington1 Courtice1 Cornwall1 Limoges1 Orléans1 Stoney Creek1 Kamloops1 Brampton1 Hamitlon1
All 48 locations
Target enrolment
to

Heart Failure trials in Canada

56 of 6553 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in Canada
Start
Recruiting
Ted Rogers Understanding of Exacerbations in Heart Failure 2: Monitor
NCT07447908Heart Failure, Heart Failure - NYHA II - IV, Heart Failure Patients, Cardiopulmonary Exercise Test
University Health Network, Toronto
Observational
360
Newmarket, Toronto
2026-06-16
Recruiting
Novo Nordisk A/S
Phase 3
5,610
Calgary, Vancouver, Winnipeg, Moncton, Halifax, Burlington, Courtice, Hamilton
2026-05-11
Recruiting
Clinical Information System Impact on Hospitalized Patients With Chronic Disease
NCT07609381Diabete Mellitus, Kidney Disease, Heart Failure, Coronary Artery Disease
University of Calgary
Observational
124,240
Calgary
2026-01-01
Not yet open
Finerenone and Cardiac Remodeling
NCT07270367Heart Failure
DrugsKerendia·Finerenone
Subodh Verma
Phase 3
156
Cambridge, North York, Toronto
2025-12
Recruiting
Oral Carnitine in Heart Failure Patients
NCT07201714Heart Failure, Carnitine Deficiency
DrugLevocarnitine
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Early Phase 1
20
London
2025-11-12
Recruiting
Cardiology Research UBC
Not applicable
300
Vancouver
2025-11-04
Recruiting
Social Prescribing to Improve Adherence and Outcomes in Women With Heart Failure
NCT06628973Heart Failure, Cardiac Failure, Heart Decompensation, Congestive Heart Failure(CHF)
McGill University Health Centre/Research Institute of the McGill University Health Centre
Not applicable
200
Montreal
2025-10-23
Recruiting
Improving Care and Mental Well-Being for Adults With Heart Failure
NCT07313657Heart Failure, Mental Health, Stress, Anxiety
Bruyère Health Research Institute.
Not applicable
7,300
Cornwall, Limoges, Orléans, Ottawa, Winchester
2025-09-26
Recruiting
Centre hospitalier de l'Université de Montréal (CHUM)
Observational
30
Montreal
2025-09-01
Not yet open
The iPeer2Peer Mentorship Program for Young Adults With Heart Disease
NCT07119216Heart Failure, Mentorship, Peer Support, Peer Support and Chronic Disease
Samantha Anthony
Not applicable
80
Toronto
2025-09
Recruiting
Novo Nordisk A/S
Phase 2
200
Vancouver, Brampton, Hamilton, Mississauga, Ottawa, Toronto, Winchester, Québec
2025-06-27
Recruiting
Pfizer
Phase 2
620
Richmond, Halifax, Greater Sudbury, Sarnia, Toronto, Winchester, Chicoutimi, Québec
2025-06-19
Recruiting
COgnitioN With VERiciGuat Evaluation in Heart Failure
NCT06601465Heart Failure, Cognitive Impairment
DrugVericiguat
University of Alberta
Phase 2
120
Calgary, Edmonton, Ottawa, Montreal
2025-06-03
Recruiting
Boehringer Ingelheim
Phase 3
4,200
Cambridge, Greater Sudbury, Hamilton, Kitchener, Mississauga, Oakville, Oshawa, Peterborough
2025-05-20
Active, closed
ASCEND CSP IDE Study
NCT06830746Heart Failure, Ventricular Arrythmia
Abbott Medical Devices
Not applicable
414
Montreal
2025-04-11
Recruiting
AstraZeneca
Phase 3
11,300
Calgary, Sherwood Park, Abbotsford British Columbia, Moncton, Saint John, St. John's, Halifax, Sydney
2025-03-14
Recruiting
Alleviant ALLAY-HFrEF Study
NCT06812533Heart Failure
Alleviant Medical, Inc.
Not applicable
350
Newmarket, Montreal, Québec
2025-03-10
Recruiting
University of Alberta
Observational
100
Edmonton, Vancouver, Toronto, Montreal
2025-02-24
Recruiting
LEFT ATRIAL MONITORING IN PATIENTS BEFORE AND AFTER MITRAL SURGERY - LAMBDA STUDY
NCT06547788Mitral Regurgitation, Mitral Valve Disease, Heart Failure
Ottawa Heart Institute Research Corporation
Not applicable
50
Ottawa
2024-12-19
Recruiting
Cytokinetics
Phase 3
1,800
Edmonton, Kelowna, Surrey, Vancouver, Victoria, Winnipeg, Kingston, London
2024-12-19
Recruiting
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
NCT06217302Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure
DrugSotagliflozin
Alessandro Doria
Phase 3
150
Calgary, Edmonton, Vancouver, Toronto, Montreal
2024-10-31
Recruiting
Colorado Prevention Center
Phase 3
2,600
Calgary, Edmonton, North Vancouver, Surrey, Victoria, Winnipeg, Greater Sudbury, Kingston
2024-08-20
Recruiting
Colorado Prevention Center
Phase 3
1,500
Edmonton, Surrey, Greater Sudbury, London, North York, Toronto, Montreal, Sherbrooke
2024-07-09
Recruiting
Breast cancEr, FITness and ExeRcise for Heart Health: The BE-FITTER Study
NCT06595147Breast Cancer, Disability Physical, Heart Failure, Cardiotoxicity
University of Alberta
Not applicable
60
Edmonton
2024-07-01
Recruiting
Boehringer Ingelheim
Phase 3
6,712
Cambridge, Hamilton, Mississauga, Oakville, Oshawa, Peterborough, Sarnia, Stoney Creek
2024-06-17
Recruiting
iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease
NCT06371937Cardiovascular Diseases, Arrythmia, Cardiomyopathies, Heart Failure
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Observational
200
London
2024-05-01
Recruiting
RAFT - Pace &Ablate
NCT06299514Atrial Fibrillation, Heart Failure, Pacemaker, Arrhythmia Atrial
Habib Khan
Not applicable
600
Victoria, Halifax, Hamilton, Kitchener, London, Newmarket, Ottawa, Toronto
2024-04-25
Active, closed
Novo Nordisk A/S
Phase 3
673
Calgary, Cambridge, Scarborough Village, Toronto, Waterloo, Montreal, Québec
2024-04-01
Recruiting
The STOP-MED CTRCD Trial
NCT06183437Heart Failure, Cardiotoxicity, Cardiac Toxicity, Antineoplastics Toxicity
Dinesh Thavendiranathan
Phase 4
335
Edmonton, Winnipeg, Hamilton, Ottawa, Toronto
2024-03-04
Recruiting
Cardiology Research UBC
Not applicable
1,360
Vancouver, Montreal, Sherbrooke
2024-03-01
Recruiting
Hamilton Health Sciences Corporation
Phase 3
2,500
Hamilton
2024-01-29
Recruiting
The Hospital for Sick Children
Observational
100
Toronto
2024-01-17
Recruiting
Colorado Prevention Center
Phase 3
5,200
Calgary, Edmonton, Kamloops, North Vancouver, Surrey, Vancouver, Winnipeg, Cambridge
2024-01-17
Recruiting
University Health Network, Toronto
Not applicable
336
Toronto
2024-01-01
Recruiting
The Hospital for Sick Children
Not applicable
55
Toronto
2024-01-01
Active, closed
Bristol-Myers Squibb
Phase 2
227
Hamilton, Toronto
2023-11-07
Recruiting
Left vs Left Randomized Clinical Trial
NCT05650658Heart Failure, Heart Failure With Reduced Ejection Fraction, AV Block, LBBB
Baylor College of Medicine
Not applicable
2,136
Edmonton, Vancouver, Victoria, Halifax, Hamilton, Newmarket, Ottawa, Toronto
2023-09-13
Recruiting
Surgical Ablation of AF Efficacy Trial
NCT05434819Atrial Fibrillation, Heart Failure
Population Health Research Institute
Not applicable
2,000
Hamilton
2023-06-01
Recruiting
Merck Sharp & Dohme LLC
Phase 2/3
342
Edmonton, Toronto, Sherbrooke
2023-05-31
Active, closed
Edwards Lifesciences
Not applicable
100
Ottawa
2023-04-01
Recruiting
Population Health Research Institute
Not applicable
891
Hamilton, Thunder Bay, Toronto
2023-01-23
Recruiting
Alleviant ALLAY-HF Study
NCT05685303Heart Failure
Alleviant Medical, Inc.
Not applicable
700
Newmarket, Montreal
2023-01-10
Recruiting
NHS Greater Glasgow and Clyde
Not applicable
3,904
Vancouver, Montreal
2022-12-22
Active, closed
RESPONDER-HF Trial
NCT05425459Heart Failure, Heart Failure, Diastolic
Corvia Medical
Not applicable
750
Vancouver, Toronto
2022-11-17
Recruiting
University of Alberta
Observational
200
Edmonton
2022-03-22
Recruiting
University of Calgary
Not applicable
100
Calgary
2021-09-15
Recruiting
Population Health Research Institute
Phase 2
130
Hamitlon, Ottawa, Toronto
2021-07-01
Active, closed
Edwards Lifesciences
Not applicable
45
Ottawa, Toronto
2019-07-10
Recruiting
Institute for Clinical Evaluative Sciences
Observational
500
Toronto
2019-02-01
Active, closed
University Health Network, Toronto
Not applicable
90
North York, Toronto
2018-11-16
Active, closed
V-Wave Ltd
Not applicable
605
Montreal, Québec
2018-09-19
Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases
Cardiac Dimensions, Inc.
Not applicable
300
Edmonton, Winnipeg, Toronto
2018-01-01
Recruiting
Christine Henri
Observational
450
Montreal
2016-07
Active, closed
Biomarkers to Classify Heart Failure
NCT02347722Heart Failure
Ottawa Heart Institute Research Corporation
Observational
511
Ottawa
2015-05
Active, closed
ASV Effects on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea.
NCT02116140Heart Failure, Obstructive Sleep Apnea, Central Sleep Apnea
Ottawa Heart Institute Research Corporation
Not applicable
60
Ottawa
2012-07
Recruiting
Medtronic
Observational
20,000
Calgary, Kingston, Montreal, Québec
1983-01
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Canadian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 November 2026. https://priyalifescience.com/clinical-trials-canada/condition/heart-failure

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Canada and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,553 studies in total at the last sync on 10 Nov 2026, 03:20 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 56 of those studies listing the condition Heart Failure.

How many Heart Failure trials are recruiting in Canada?

44 of the 56 studies on this page are recruiting new participants as of the 10 Nov 2026, 03:20 UTC sync. A further 2 have not yet opened recruitment, 10 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Heart Failure), 56 studies
PhaseStudiesRecruitingShare
Not applicable251744.6%
Phase 3121021.4%
Observational111019.6%
Phase 2548.9%
Early Phase 1111.8%
Phase 2/3111.8%
Phase 4111.8%

Most active sponsors

Lead sponsors with the most studies (Heart Failure)
Lead sponsorStudiesRecruiting
University of Alberta44
Colorado Prevention Center33
Novo Nordisk A/S32
Ottawa Heart Institute Research Corporation31
Population Health Research Institute33
University Health Network, Toronto32
Alleviant Medical, Inc.22
Boehringer Ingelheim22
Cardiology Research UBC22
Edwards Lifesciences20
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.