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Medtronic Cardiovascular clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA, UK, China and Ireland registers with Medtronic Cardiovascular as lead sponsor. Synced 26 Sep 2026
17Current trials
7Recruiting now
0Drugs in these trials
4Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Medtronic Cardiovascular is the lead sponsor of 17 current clinical trials in our USA, UK, China and Ireland registers. 7 are recruiting patients now. The most common phase is Not applicable. The most-studied condition is AAA - Abdominal Aortic Aneurysm.

Company profile on this site (news, sites, medicines, approvals): Medtronic Ireland (IE) →

ClinicalTrials.gov trials by status

  • Recruiting741%
  • Active, closed1059%

Trials by phase

  • Not applicable1588%
  • Observational212%
01

Clinical trials sponsored by Medtronic Cardiovascular

17 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
Harmony TPV EMEA PMS
NCT06906926 · ClinicalTrials.gov ↗ · Severe Pulmonary Valve Regurgitation
Not applicable Recruiting 2025-07 Ireland
Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial
NCT05496998 · ClinicalTrials.gov ↗ · Mitral Regurgitation
Not applicable Recruiting 2023-02 UK
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
NCT05378347 · ClinicalTrials.gov ↗ · Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder), Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
Not applicable Recruiting 2023-01 UK, USA, China
Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation
NCT07321899 · ClinicalTrials.gov ↗ · Severe Tricuspid Regurgitation
Not applicable Recruiting 2026-09 USA
Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System China Study(ATHENA)
NCT07754318 · ClinicalTrials.gov ↗ · AAA - Abdominal Aortic Aneurysm
Not applicable Recruiting 2026-08 China
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
NCT03242642 · ClinicalTrials.gov ↗ · Mitral Valve Regurgitation
Not applicable Recruiting 2017-10 USA
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
NCT06777368 · ClinicalTrials.gov ↗ · Aortic Stenosis
Observational Recruiting 2025-02 USA
Evolut™ EXPAND TAVR II Pivotal Trial
NCT05149755 · Moderate Aortic Valve Stenosis
Not applicable Active, closed 2022-04 Ireland, UK, USA
Endurant CHevAr New Indication Trial: ENCHANT
NCT03320252 · AAA - Abdominal Aortic Aneurysm
Observational Active, closed 2017-10 UK
Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients
NCT02701283 · Aortic Valve Stenosis
Not applicable Active, closed 2016-03 USA
Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR Transseptal System
NCT02322840 · Mitral Valve Insufficiency
Not applicable Active, closed 2015-04 UK, USA
Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).
NCT01586910 · ClinicalTrials.gov ↗ · Severe Aortic Stenosis
Not applicable Active, closed 2012-04 UK, USA
SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial
NCT04722250 · ClinicalTrials.gov ↗ · Symptomatic Aortic Stenosis, Aortic Valve Stenosis, Aortic Valve Replacement
Not applicable Active, closed 2021-04 UK, USA
Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study
NCT03635424 · ClinicalTrials.gov ↗ · Bicuspid Aortic Valve
Not applicable Active, closed 2018-10 USA
TTVR Early Feasibility Study
NCT04433065 · ClinicalTrials.gov ↗ · Tricuspid Regurgitation
Not applicable Active, closed 2020-10 USA
Harmony TPV Post-Approval Study
NCT05077774 · ClinicalTrials.gov ↗ · Congenital Heart Disease, Tetrology of Fallot, RVOT Anomaly
Not applicable Active, closed 2021-10 USA
Evolut PRO China Clinical Study
NCT04982588 · ClinicalTrials.gov ↗ · Severe, Symptomatic Aortic Stenosis
Not applicable Active, closed 2021-07 China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Conditions in Medtronic Cardiovascular trials

22 conditions
AAA - Abdominal Aortic Aneurysm2Aortic Valve Stenosis2Moderate Aortic Valve Stenosis1Severe Pulmonary Valve Regurgitation1Mitral Valve Insufficiency1Mitral Regurgitation1Abdominal Aortic Aneurysm1Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder)1Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)1Severe Aortic Stenosis1Symptomatic Aortic Stenosis1Aortic Valve Replacement1Bicuspid Aortic Valve1Severe Tricuspid Regurgitation1Tricuspid Regurgitation1Mitral Valve Regurgitation1Congenital Heart Disease1Tetrology of Fallot1RVOT Anomaly1Pulmonary Regurgitation1Aortic Stenosis1Severe, Symptomatic Aortic Stenosis1
03

By trial register

RegisterTrialsRecruiting
Clinical trials in USA124
Clinical trials in UK72
Clinical trials in China32
Clinical trials in Ireland21

A trial with sites in more than one country appears in each of those registers.

04

Other sponsors in AAA - Abdominal Aortic Aneurysm

SponsorTrials
Endologix1

Sponsors with the most current trials registered for this condition.

05

Questions about Medtronic Cardiovascular trials

How many clinical trials does Medtronic Cardiovascular sponsor?

Medtronic Cardiovascular is the lead sponsor of 17 current trials on ClinicalTrials.gov in our USA, UK, China and Ireland registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Medtronic Cardiovascular trials recruiting?

Yes. 7 of its 17 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Does Medtronic Cardiovascular have clinical trials in Ireland?

Yes. 2 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.