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Clinical trial register · United States · industry-sponsored

Lung Cancer Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 04 Oct 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4948
Recruiting now
open to new participants
2193
Lead sponsors
across recruiting studies
Top states
California 14 Florida 13 Texas 10 New York 10 Ohio 9
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Recruitment status
Phase
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Lung Cancer trials in the USA

31 of 9112 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
NCT07499674Lung Cancer, Lung Metastases
Vergent Bioscience, Inc.
Phase 3
132
California, Colorado, Florida, Michigan, Minnesota, Pennsylvania, Texas
2026-03-31
Active, closed
A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
NCT07128199Lung Cancer, Adjuvant, Post-surgical, EGFR
Taiho Oncology, Inc.
Phase 3
360
Alaska, California, District of Columbia, Florida, Georgia, Illinois, Michigan, New Jersey
2025-12-22
Recruiting
Sample Collection for Ongoing Research and Product Evaluation Study
NCT07318051Breast Cancer, Lung Cancer, Muscle Invasive Bladder Cancer, Rectal Cancer
Natera, Inc.
Observational
9,600
Texas
2025-07-21
Not yet open
A Phase 3 Study of 99mTC-EC-DG SPECT/CT Versus PET/CT in Lung Cancer
NCT01394679Lung Cancer
Cell>Point LLC
Phase 3
154
Illinois
2025-05-01
Recruiting
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
NCT06618287Lung Cancer, Breast Cancer
Bristol-Myers Squibb
Phase 1/2
416
Alabama, Florida, Iowa, Missouri, New Jersey, Ohio, Oregon, Pennsylvania
2025-02-04
Active, closed
A Clinical Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) to Treat Newly-diagnosed Metastatic Non-small Cell Lung Cancer (MK-3475A-F84)
NCT06698042Lung Cancer, Non-Small Cell Lung Cancer
Merck Sharp & Dohme LLC
Phase 3
67
California, Illinois, New York, Ohio
2024-11-21
Active, closed
Prospective Evaluation of the Tool-in-lesion Technology of the Galaxy System in Routine Clinical Practice
NCT06685133Lung Cancer, Lung; Nodule
Noah Medical
Observational
50
Tennessee, Virginia
2024-11-08
Active, closed
A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
NCT06644768Non-small Cell Lung Cancer, Lung Cancer
Daiichi Sankyo
Phase 1/2
137
California, Florida, Kentucky, Minnesota, New York, Pennsylvania, Virginia
2024-10-30
Active, closed
Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer
NCT06125197Lung Cancer
TILT Biotherapeutics Ltd.
Phase 1
22
California
2024-07-23
Active, closed
Evaluation of Improved Onboard Patient Imaging
NCT06187103Head and Neck Cancer, Breast Cancer, Upper Gastrointestinal Cancer, Lung Cancer
Varian, a Siemens Healthineers Company
Observational
40
Maryland
2024-07-10
Active, closed
A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live CoActive Exercise Coaching and Personalized Digital Application on Cancer Survivors' Quality of Life
NCT06397651Breast Cancer, Lung Cancer, Prostate Cancer, Colorectal Cancer
Complement Theory Inc.
Not applicable
146
Delaware
2024-05-12
Recruiting
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
NCT06060613Tumor Skin, Metastatic Melanoma, Melanoma, Lung Cancer
Obsidian Therapeutics, Inc.
Phase 1/2
208
California, Florida, Kentucky, New York, Ohio, Pennsylvania, Texas
2023-10-25
Active, closed
Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung
NCT05987189Lung Cancer
Hummingbird Diagnostics
Observational
2,000
Georgia, Louisiana, Massachusetts, Michigan, New York, Pennsylvania, Texas, Utah
2023-10-18
Active, closed
Real World Registry for Use of the Ion Endoluminal System
NCT06004440Lung Cancer, Multiple Pulmonary Nodules, Lung Neoplasms, Respiratory Tract Neoplasms
Intuitive Surgical
Observational
1,301
Florida, Illinois, Kansas, Louisiana, Michigan, Minnesota, New York, North Carolina
2023-09-21
Recruiting
Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
NCT05974150Breast Cancer, Lung Cancer, Multiple Myeloma, Ovarian Cancer
Carevive Systems, Inc.
Observational
25
Connecticut, Illinois, North Carolina, Ohio
2023-07-19
Active, closed
Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
NCT05887492Non Small Cell Lung Cancer, Solid Tumors, Adult, Lung Cancer, Lung Adenocarcinoma
Tango Therapeutics, Inc.
Phase 1/2
126
California, Colorado, Florida, Massachusetts, Michigan, New York, Tennessee, Texas
2023-06-12
Active, closed
Study of Novel Treatment Combinations in Patients With Lung Cancer
NCT05633667Lung Cancer, Advanced or Metastatic Non-Small-Cell Lung Cancer, Resectable Non-Small-Cell Lung Cancer
Gilead Sciences
Phase 2
192
Arizona, Indiana, Kentucky, Missouri, Ohio, Oregon
2023-03-16
Active, closed
Real World Treatment Experience of Patients With Breast, Lung, or GI Cancer or Multiple Myeloma Using Remote Symptom Monitoring
NCT05587972Breast Cancer, Lung Cancer, Gastrointestinal Cancer, Multiple Myeloma
Carevive Systems, Inc.
Not applicable
100
Ohio
2022-10-06
Active, closed
A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
NCT05485974Lung Cancer, Non Small Cell Lung Cancer, Colorectal Cancer, Cancer of Pancreas
HUYABIO International, LLC.
Phase 1
44
California, Florida, Michigan, Missouri, Ohio
2022-08-01
Recruiting
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
NCT06426628Pulmonary Nodule, Solitary, Lung Cancer
Veracyte, Inc.
Observational
2,400
Connecticut, Florida, Illinois, Kansas, Kentucky, Louisiana, Maryland, Massachusetts
2022-07-18
Recruiting
Comprehensive Outcomes for After Cancer Health
NCT05349227Ovarian Cancer, Breast Cancer, Lung Cancer, Gastric Cancer
Pack Health
Not applicable
625
Florida, Massachusetts, Nebraska, New York, Ohio, Texas
2022-06-23
Active, closed
CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung
NCT05306288Lung Cancer
Delfi Diagnostics Inc.
Observational
11,935
Alabama, California, Colorado, Connecticut, Florida, Georgia, Illinois, Kentucky
2022-04-07
Active, closed
Screening for High Frequency Malignant Disease
NCT05117840Lung Cancer
Guardant Health, Inc.
Observational
12,000
Alabama, Arkansas, California, Connecticut, District of Columbia, Florida, Georgia, Illinois
2022-01-13
Recruiting
A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies
NCT04678648Advanced Malignant Solid Neoplasm, RAS Mutation, Lung Cancer, Colon Cancer
RasCal Therapeutics, Inc.
Phase 1
134
California, Colorado, Tennessee
2021-03-03
Active, closed
Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer
NCT04736173Non Small Cell Lung Cancer, Nonsquamous Non Small Cell Lung Cancer, Squamous Non Small Cell Lung Cancer, Lung Cancer
Arcus Biosciences, Inc.
Phase 2
169
Georgia, Texas, Virginia
2021-02-08
Active, closed
Tempus Priority Study: A Pan-tumor Observational Study
NCT05179824Breast Cancer, Prostate Cancer, Bladder Cancer, Lung Cancer
Tempus AI
Observational
1,000
Texas
2020-10-19
Recruiting
Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®
NCT03290534Lung Cancer, Lung Cancer Stage I, Lung Cancer Stage II
CivaTech Oncology
Phase 2
40
New York
2019-03-13
Recruiting
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
NCT03556228Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer, Non-Small Cell Lung Cancer
VM Oncology, LLC
Phase 1/2
242
California, Connecticut, District of Columbia, Florida, New Jersey, New Mexico, New York, Ohio
2018-06-08
Recruiting
Collection of Sputum and Labeling for Lung Cancer
NCT03457415Lung Cancer
bioAffinity Technologies Inc.
Observational
500
New Jersey, New Mexico, Texas
2018-03-01
Active, closed
An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
NCT02955940Pancreatic Cancer, Colorectal Cancer (CRC), Breast Cancer, Lung Cancer
Incyte Corporation
Phase 2
10
California, Kentucky, New York, Tennessee, Texas
2016-11-30
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 4 October 2026. https://priyalifescience.com/clinical-trials-usa/condition/lung-cancer

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,112 studies in total at the last sync on 04 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 31 of those studies listing the condition Lung Cancer.

How many Lung Cancer trials are recruiting in the US?

11 of the 31 studies on this page are recruiting new participants as of the 04 Oct 2026, 03:16 UTC sync. A further 1 have not yet opened recruitment, 19 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Lung Cancer), 31 studies
PhaseStudiesRecruitingShare
Observational11435.5%
Phase 1/25316.1%
Phase 25116.1%
Phase 34112.9%
Not applicable319.7%
Phase 1319.7%

Most active sponsors

Lead sponsors with the most studies (Lung Cancer)
Lead sponsorStudiesRecruiting
Carevive Systems, Inc.21
Arcus Biosciences, Inc.10
AstraZeneca10
bioAffinity Technologies Inc.11
Bristol-Myers Squibb11
Cell>Point LLC10
CivaTech Oncology11
Complement Theory Inc.10
Daiichi Sankyo10
Delfi Diagnostics Inc.10

Top states

Top states (Lung Cancer), by number of studies with a site there
StateStudies
California14
Florida13
New York10
Texas10
Ohio9
Illinois8
Kentucky6
Michigan6
Connecticut5
Georgia5
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.