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Priya Life Science Clinical trial register
Trackers› Clinical trials› Aortic Valve Disease
Clinical trial register · United States · industry-sponsored

Aortic Valve Disease Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9128 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 04 Nov 2026, 03:16 UTC
9128
Studies in scope
industry-sponsored, all four open statuses
4968
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 6 Michigan 6 Florida 5 District of Columbia 5 Illinois 5
Narrow the registerReset
Recruitment status
Phase
Target enrolment
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Aortic Valve Disease trials in the USA

11 of 9128 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
NCT07276711Aortic Valve Stenosis, Aortic Stenosis, Aortic Valve Disease
EmStop Inc
Not applicable
663
California, Florida, Louisiana, Michigan, North Carolina, South Dakota, Texas
2026-05-12
Active, closed
The JenaValve ALIGN-AR LVAD Registry
NCT06594705Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency, Aortic Valve Disease
JenaValve Technology, Inc.
Not applicable
50
California, District of Columbia, Georgia, Illinois, Michigan, Minnesota, Missouri, New York
2024-12-09
Active, closed
Avalus Ultra Post-Approval Study (PAS)
NCT06506903Aortic Valve Disease
Medtronic Cardiac Surgery
Not applicable
190
Connecticut, Florida, Georgia, Illinois, Michigan, Minnesota, New York, Ohio
2024-11-20
By invitation
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
NCT05932615Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder
Abbott Medical Devices
Not applicable
1,500
Alabama, Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Georgia
2024-03-15
Active, closed
Evaluation of Safety and Effectiveness of the EMBLOK EPS During TAVR
NCT05295628Aortic Valve Stenosis, Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Valve Replacement
Emblok, Inc.
Not applicable
532
Arizona, California, Connecticut, District of Columbia, Illinois, Iowa, Kansas, Louisiana
2023-10-17
Active, closed
J-Valve TF Early Feasibility Study
NCT06034028Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Regurgitation
JC Medical, Inc., an affiliate of Edwards Lifesciences LLC
Not applicable
25
Arizona, District of Columbia, Illinois, Louisiana, New York, Ohio, Texas, Washington
2023-10-16
Active, closed
JOTEC GmbH
Observational
108
Pennsylvania, Texas, Virginia
2021-10-20
Recruiting
Valved Graft PMCF Study
NCT04754217Aortic Valve Disease, Ascending Aorta Abnormality, Aortic Dissection
Abbott Medical Devices
Observational
260
Alabama, Michigan, North Carolina, Pennsylvania
2021-07-13
Active, closed
The JenaValve ALIGN-AR Pivotal Trial
NCT04415047Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency, Aortic Valve Disease
JenaValve Technology, Inc.
Not applicable
180
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Maryland, Michigan
2020-05-22
Active, closed
Abbott Medical Devices
Observational
20
California, Florida, Georgia, Mississippi, Ohio, Texas
2019-10-24
Active, closed
Early Feasibility Study for the Foldax Tria Aortic Heart Valve
NCT03851068Aortic Valve Disease, Aortic Valve Stenosis
Foldax, Inc
Not applicable
40
Indiana, Kansas, Michigan, Ohio
2019-06-18
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 4 November 2026. https://priyalifescience.com/clinical-trials-usa/condition/aortic-valve-disease

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,128 studies in total at the last sync on 04 Nov 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 11 of those studies listing the condition Aortic Valve Disease.

How many Aortic Valve Disease trials are recruiting in the US?

2 of the 11 studies on this page are recruiting new participants as of the 04 Nov 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 8 are active but closed to new participants, and 1 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Aortic Valve Disease), 11 studies
PhaseStudiesRecruitingShare
Not applicable8172.7%
Observational3127.3%

Most active sponsors

Lead sponsors with the most studies (Aortic Valve Disease)
Lead sponsorStudiesRecruiting
Abbott Medical Devices31
JenaValve Technology, Inc.20
Emblok, Inc.10
EmStop Inc11
Foldax, Inc10
JC Medical, Inc., an affiliate of Edwards Lifesciences LLC10
JOTEC GmbH10
Medtronic Cardiac Surgery10

Top states

Top states (Aortic Valve Disease), by number of studies with a site there
StateStudies
California6
Michigan6
District of Columbia5
Florida5
Georgia5
Illinois5
Arizona4
Ohio4
Texas4
Louisiana3
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.