Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease
Condition(s) studied
Study summary
Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. This study will assess how effective Foslevodopa/Foscarbidopa is in treating adult participants earlier within advanced Parkinson disease under routine clinical practice.
Foslevodopa/Foscarbidopa is an approved drug for the treatment of Parkinson's Disease. Approximately 100 adult participants who are prescribed Foslevodopa/Foscarbidopa by their doctors will be enrolled across approximately 40 sites across the world.
Participants will receive Foslevodopa/Foscarbidopa subcutaneous infusion as prescribed by their physician. Participants will be followed for up to 6 months.
There are no additional examinations due to the study but the participants and caregivers will need to fill several questionnaires to generate data on their motor function and well-being
Eligibility
Primary outcome measure(s)
- Change From Baseline in OFF Time (hours) as measured by modified Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) IV — Up to approximately 6 months
The Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) is an investigator-used rating tool to follow the longitudinal course of Parkinson's Disease (PD)
Trial sites (10)
| Facility | City | Region | Status |
|---|---|---|---|
| Texas Movement Disorder Specialists /ID# 278565 | Georgetown | Texas | Recruiting |
| Shaare Zedek Medical Center /ID# 276209 | Jerusalem | Jerusalem | Recruiting |
| The Chaim Sheba Medical Center /ID# 276210 | Ramat Gan | Tel Aviv | Recruiting |
| Tel Aviv Sourasky Medical Center /ID# 276212 | Tel Aviv | Tel Aviv | Recruiting |
| Hadassah Medical Center-Hebrew University /ID# 276211 | Jerusalem | Israel | Recruiting |
| Fundeni Clinical Institute /ID# 277490 | Bucharest | Bucharest | Recruiting |
| Arcadia Spitale Si Centre Medicale /Id# 277525 | Iași | Iaşi | Recruiting |
| Neurotim Med /ID# 277500 | Timișoara | Timiș County | Recruiting |
| Spitalul Clinic Judetean De Urgenta Brasov /ID# 277499 | Brasov | Romania | Not Yet Recruiting |
| University Hospitals Plymouth NHS Trust /ID# 284977 | Plymouth | Devon | Recruiting |
More AbbVie trials in the UK
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07227896 on ClinicalTrials.gov ↗ ← All trials in the UK