Solid Tumor Clinical Trials in the UK

Solid Tumor Trials in the UK

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a UK site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full UK registry across all sponsors is far larger. UK studies may also be registered separately on ISRCTN.

Status

Study

Lead sponsor

Phase

Enrol

UK sites

Start

Recruiting

Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors

NCT07151040Solid Tumor, Colorectal Cancer (CRC), Squamous Cell Carcinoma of Head and Neck, Non-Small Cell Lung Cancer (NSCLC)

One-carbon Therapeutics AB

Phase 1/2

Newcastle upon Tyne

2025-08-22

Active, closed

A Dose Escalation and Expansion Trial With BYON4228 Alone and in Combination in Patients With Advanced or Metastatic Solid Tumors

NCT06932952Solid Tumor

Byondis B.V.

Phase 1

Manchester, Sutton

2025-05-07

Recruiting

Ixovex-1 Single Agent and Combination Therapy

NCT06549946Solid Tumor, Head and Neck Cancer

Psivac Ltd

Phase 1/2

London

2024-12-17

Recruiting

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

NCT06603844Solid Tumor

Corbus Pharmaceuticals Inc.

Phase 1/2

156

Newcastle upon Tyne, Manchester, Birkenhead, Edinburgh, Glasgow, London

2024-12-04

Recruiting

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

NCT06619587Solid Tumor

Genentech, Inc.

Phase 1

410

Edinburgh, London, Manchester, Sutton

2024-11-14

Recruiting

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

NCT06401356Hematologic Malignancy, Solid Tumor, Advanced Malignancies

Novartis Pharmaceuticals

Phase 3

Cardiff, Glasgow, London

2024-08-13

Recruiting

Study of STP938 (Dencatistat) in Advanced Solid Tumours

NCT06297525Solid Tumor

Step Pharma, SAS

Phase 1

Glasgow, London, Manchester

2024-08-02

Active, closed

Study of GS-4528 in Adults With Solid Tumors

NCT05840224Solid Tumor

Gilead Sciences

Phase 1

182

London, Sutton

2023-05-11

Recruiting

A Study of PYX-201 in Advanced Solid Tumors

NCT05720117Solid Tumor, Advanced Solid Tumor

Pyxis Oncology, Inc

Phase 1

330

London

2023-03-14

Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

NCT05176483Renal Cell Carcinoma (RCC), Metastatic Castration-Resistant Prostate Cancer (mCRPC), Urothelial Carcinoma (UC), Solid Tumor

Exelixis

Phase 1

1,394

Cambridge, London, Middlesex

2021-12-14

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

NCT04300556Solid Tumor

Eisai Inc.

Phase 1/2

182

Belfast, Glasgow, Manchester, Preston, London, Northwood, Cardiff, Sutton

2020-08-06

Active, closed

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

NCT03006172Breast Cancer, Solid Tumor

Genentech, Inc.

Phase 1

200

Surrey, London

2016-12-13

Recruiting

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

NCT02332668Melanoma, Lymphoma, Solid Tumor, Classical Hodgkin Lymphoma

Merck Sharp & Dohme LLC

Phase 1/2

370

London

2015-03-19

Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a UK investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 18 September 2026. https://priyalifescience.com/clinical-trials-uk/condition/solid-tumor

Query this register directly

GET /api/trials?country=uk&status=recruiting&format=json Try it now →