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Clinical trial register · United Kingdom · industry-sponsored

Rheumatoid Arthritis Trials in the UK

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a UK site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full UK registry across all sponsors is far larger. UK studies may also be registered separately on ISRCTN.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 2852 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 17 Sep 2026, 08:23 UTC
2852
Studies in scope
industry-sponsored, all four open statuses
1378
Recruiting now
open to new participants
540
Lead sponsors
across recruiting studies
Top sites
London 8 Edinburgh 3 Glasgow 3 Leeds 2 Barnet 2
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca4 Zimmer Biomet4 Medacta International SA1 AnaptysBio, Inc.1 Galvani Bioelectronics1
Site city
London8 Edinburgh3 Glasgow3 Leeds2 Barnet2
All 32 cities
Target enrolment
to
18 of 2852 studies
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Status
Study
Lead sponsor
Phase
Enrol
UK sites
Start
Recruiting
A Study of AZD0120 in Autoimmune Diseases
NCT07295847Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Rheumatoid Arthritis
AstraZeneca
Phase 1
27
Edinburgh, London
2026-01-09
Recruiting
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
NCT07276581Rheumatoid Arthritis
AstraZeneca
Phase 2
320
Glasgow, Leeds, Luton, Staffordshire
2025-12-15
Recruiting
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
NCT07137598Rheumatoid Arthritis
Hoffmann-La Roche
Phase 2
160
Leicester, Doncaster, Newcastle upon Tyne, Barnet
2025-12-05
Recruiting
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
NCT07201558Rheumatoid Arthritis, Systemic Lupus Erythematosus
AstraZeneca
Phase 1
48
London
2025-12-02
Recruiting
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
NCT06916806Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies, Rheumatoid Arthritis
AstraZeneca
Phase 1
72
Glasgow, London, Southampton
2025-05-01
Active, closed
A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis
NCT06754462Rheumatoid Arthritis
Immunovant Sciences GmbH
Phase 2
120
Edinburgh, London, North Shields, Wolverhampton
2025-01-10
Active, closed
A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Rheumatoid Arthritis (RENOIR)
NCT06041269Rheumatoid Arthritis
AnaptysBio, Inc.
Phase 2
420
London, Manchester
2023-08-31
Recruiting
Evaluation of the PHENO4U Data Platform in Patients Undergoing Total Knee Arthroplasty
NCT05302934Degenerative Osteoarthritis, Rheumatoid Arthritis, Posttraumatic Arthropathy, Chronic Instability of Knee
Aesculap AG
Observational
600
Nottingham
2022-09-28
Recruiting
Safety of Splenic Stimulation for RA
NCT04955899Rheumatoid Arthritis
Galvani Bioelectronics
Not applicable
5
Glasgow
2021-10-20
Active, closed
A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate
NCT04909801Rheumatoid Arthritis
Bristol-Myers Squibb
Phase 3
338
Cannock, Hull, London
2021-09-15
Active, closed
Prospective Observational Study of Filgotinib in Subjects With Rheumatoid Arthritis
NCT04871919Rheumatoid Arthritis
Alfasigma S.p.A.
Observational
1,304
Aberdeen, Barnet, Coventry, Doncaster, Dundee, Edinburgh, Liverpool, London
2021-05-11
Active, closed
A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Adults With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate
NCT02629159Rheumatoid Arthritis
AbbVie
Phase 3
1,629
London, Portsmouth, Warrington
2015-12-01
Active, closed
BC Study of G7 Cup and Compatible Femoral Stems
NCT03456622Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
Zimmer Biomet
Observational
230
Bournemouth
2015-11
Active, closed
Zimmer POLAR Persona - TKA (EMEA Study)
NCT02337244Severe Knee Pain, Severe Knee Disability, Osteoarthritis, Rheumatoid Arthritis
Zimmer, GmbH
Observational
777
Leeds, Clydebank, Harrogate, Newcastle
2013-11-18
Active, closed
Comprehensive Nano - Post Market Clinical Follow-Up Study
NCT03423953Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Revision
Zimmer Biomet
Observational
194
Liverpool
2013-10-30
Active, closed
The Medacta International GMK Sphere Post-Marketing Surveillance Study
NCT02199600Arthritis, Traumatic Arthritis, Rheumatoid Arthritis, Poly-arthritis
Medacta International SA
Not applicable
500
Whitechapel, Stanmore, Epsom
2012-10
Active, closed
A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee
NCT01542580Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity
Zimmer Biomet
Observational
255
Birmingham
2012-03
Active, closed
Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System
NCT01480440Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture
Zimmer Biomet
Observational
200
Blackburn
2011-01
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a UK investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 19 September 2026. https://priyalifescience.com/clinical-trials-uk/condition/rheumatoid-arthritis

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Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the UK Pharma Salary Guide, or see the Ireland, EU and USA registers.