Ireland
--:--IST
Recruiting Not applicable

TPVB or SPSIPB in Pain Management After VATS

NCT06426706 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2025-01-03
Last updated
2025-01-03

Condition(s) studied

Video-assisted Thoracoscopic SurgeryParavertebral BlockSerratus Posterior Superior Intercostal Plane BlockRegional Anesthesia Morbidity

Investigational drug(s) / intervention(s)

Serratus Posterior Superior Intercostal Plane BlockParavertebral Block

Serratus Posterior Superior Intercostal Plane Block: Before the induction of general anesthesia, under aseptic conditions, serratus posterior superior intercostal plane block will be performed with a single dose of 30 ml of %0,25 bupivacaine with ultrasound guidance, by the senior anaesthesiologist.

Paravertebral Block: Before the induction of general anesthesia, under aseptic conditions, paravertebral block will be performed with a single dose of 30 ml of %0,25 bupivacaine with ultrasound guidance, by the senior anaesthesiologist.

Study summary

The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic surgery (VATS). The main questions it aims to answer are:

How will the total perioperative opioid consumption of the patients receiving two different blocks change? How will TPVB and SPSIPB effect the patients' numeric rating scores for pain in the postoperative 24-hour period? How will TPVB and SPSIPB effect the incidence of opioid related side effects?

Participants will be divided in two groups:

TPVB group will receive a TPVB before the surgery. SPSIPB group will receive a SPSIPB nerve block before the surgery. Researchers will compare the results between the groups to see the postoperative effects concerning opioid consumption as well as the pain scores, respiratory parameters and opioid associated side effects.

The hypothesis of this study is that participants receiving SPSIPB for VATS will have a less total opioid consumption 24 hours postoperatively.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Patients between the age of 18-80 undergoing video-assisted thoracoscopic surgery Exclusion Criteria: * Allergy to local anaesthetics Chronic opioid use history Patients with psychiatric disorders Patients who are not open to communication Patients with chronic organ failure Patients that do not give consent Patients that need emergency surgery within the first 24 hours of the initial surgery

Primary outcome measure(s)

  • Total opioid consumption — 24 hours post-surgery
    all consumed opioids will be converted in morphine equivalents and then added to reach the total dosage

Trial sites (1)

FacilityCityRegionStatus
Koc University Istanbul Turkey (Türkiye) Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06426706 on ClinicalTrials.gov ↗ ← All trials in Turkey