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Recruiting Not applicable

ESP vs SPSIP Block in VATS Analgesia

NCT07232940 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2025-11-15
Last updated
2025-12-16

Condition(s) studied

Video-assisted Thoracoscopic Surgery (VATS)Serratus Posterior Superior Intercostal Plane Block

Investigational drug(s) / intervention(s)

Postoperative analgesia management(SPSIPB)Postoperative analgesia management(ESPB)

Postoperative analgesia management(SPSIPB): A high-frequency linear ultrasound probe (GE ML6-15-D Matrix Linear) will be covered with a sterile sheath, and the T3 level will be identified just above the medial border of the scapula. After visualizing the trapezius, rhomboid major, and serratus posterior superior muscles (from superficial to deep), 30 mL of 0.25% bupivacaine (Buvicaine 0.5%®, Polifarma, Tekirdağ, Türkiye) containing 7.5 µg epinephrine (1:200,000) (Adrenalin Bas Galen®; Galen, İstanbul, Türkiye) will be administered as the local anesthetic solution.

Postoperative analgesia management(ESPB): A high-frequency linear ultrasound probe (GE ML6-15-D Matrix Linear) will be covered with a sterile sheath. At the T5 vertebral level, the erector spinae muscle layers and the transverse process of the T5 vertebra, located immediately beneath them, will be identified. After confirming the transverse process, 30 mL of 0.25% bupivacaine (Buvicaine 0.5%®, Polifarma, Tekirdağ, Türkiye) containing 7.5 µg epinephrine (1:200,000) (Adrenalin Bas Galen®; Galen, İstanbul, Türkiye) will be administered as the local anesthetic solution.

Study summary

Video-assisted thoracoscopic surgery (VATS) is a minimally invasive procedure performed through small thoracic incisions, but postoperative pain remains significant due to tissue and rib trauma. Poorly controlled pain may lead to chronic postoperative pain; therefore, optimal analgesia is essential.

According to PROSPECT guidelines, erector spinae plane block (ESPB) or paravertebral block (PVB) are recommended for VATS. The recently defined serratus posterior superior intercostal plane block (SPSIPB) provides analgesia between C3-T10 levels, but its efficacy compared with ESPB has not been studied.

This study aims to compare postoperative analgesic efficacy and patient satisfaction between ESPB and SPSIPB in VATS patients.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Patients aged 18-65 years with ASA physical status I-III who will undergo elective video-assisted thoracoscopic surgery (VATS) will be included. Exclusion Criteria: * Patients who do not consent to participate in the study Patients with coagulopathy Patients with a history of local anesthetic allergy or toxicity Patients with hepatic or renal failure Patients with uncontrolled diabetes Patients with uncontrolled hypertension Mentally disabled patients Patients receiving chronic pain treatment (opioid users) Patients using antidepressant medication Patients with neuropathic pain Mentally disabled patients Presence of infection at the injection site Pregnant or breastfeeding women, or those with suspected pregnancy

Primary outcome measure(s)

  • opioid consumption — 0, 2, 4, 8, 16 and 24 hours
    Tramadol will be prepared as 5mg/ml and patient-controlled analgesia will be administered without basal infusion, with a locking time of 20 minutes and a bolus dose of 10mg.

Trial sites (1)

FacilityCityRegionStatus
Bursa City Hospital Bursa Nilüfer Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07232940 on ClinicalTrials.gov ↗ ← All trials in Turkey