Ireland
--:--IST
Starting soon Observational

Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia

NCT07757984 · tracked via the Priya Life Science Taiwan tracker
Phase
Observational
Started
2026-09-01
Last updated
2026-08-11

Condition(s) studied

SarcopeniaNerve Block

Investigational drug(s) / intervention(s)

sarcopeniaNon-sarcopeniaGeneral AnesthesiaNerve Block

sarcopenia: Patients identified with sarcopenia based on preoperative muscle assessment.

Non-sarcopenia: Patients with normal muscle mass based on preoperative muscle assessment.

General Anesthesia: received general anesthesia alone

Nerve Block: general anesthesia combined with nerve block

Study summary

The goal of this observational study is to learn about the impact of sarcopenia (muscle loss) on the efficacy of regional nerve blocks and postoperative recovery in patients undergoing upper extremity surgery. The main questions it aims to answer are:

1. Does sarcopenia affect the onset time and success rate of peripheral nerve blocks?
2. How does sarcopenia influence postoperative pain control and opioid consumption compared to patients receiving pure general anesthesia?

Participants will undergo a preoperative muscle assessment, which includes a chair stand test and a brief ultrasound of the thigh muscle. Researchers will then observe and record their nerve block onset time (if applicable), postoperative pain scores, and recovery metrics during their hospital stay up to postoperative day 2.

Eligibility

Sex
ALL
Min age
50 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age\>=50 years old * ASA I-III * Receiving upper limb surgery under general anesthesia Exclusion Criteria: * Severe cognitive impairment or inability to cooperate with pain and motor assessment * Pre-existing neuropathy of the musculocutaneous, median, radial or ulnar nerve * (for nerve block group) Contraindications to regional nerve blockade

Primary outcome measure(s)

  • time to first rescue analgesia — From the completion of surgery up to Postoperative Day 2

Trial sites (1)

FacilityCityRegionStatus
ChangGung Memorial Hospital Taoyuan Taiwan
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07757984 on ClinicalTrials.gov ↗ ← All trials in Taiwan