Multimodal Resistance and Relaxation TrainingHome-Based Resistance Exercise Training
Multimodal Resistance and Relaxation Training: A 16-week multimodal program consisting of resistance exercise and relaxation training. Participants undergo two sessions per week: one weekly session is conducted under the supervision of a physical therapist at Taipei Tzu Chi Hospital, and one weekly session is self-directed and performed by the participant in a home setting. The resistance exercise portion utilizes progressive elastic band training
Home-Based Resistance Exercise Training: A 16-week self-directed resistance exercise program. The intervention consists of two sessions per week performed independently by the participant in a home setting. The exercise regimen utilizes progressive elastic band training and is conducted without direct therapist supervision
Study summary
This study evaluates the comparative effectiveness of a multi-modal facility-based rehabilitation program (therapist-led resistance exercise and relaxation training) versus a self-directed home-based resistance exercise program in post-treatment breast cancer survivors. Participants in both intervention groups will complete a 16-week program consisting of two exercise sessions per week.The multimodal, therapist-led approach is hypothesized to result in superior improvements in physical performance and quality of life outcomes compared to self-directed home exercise
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Histologically confirmed primary breast cancer
* Stage I-III non-metastatic breast cancer following lumpectomy or mastectomy
* Completed adjuvant chemotherapy (with or without radiotherapy)
* Age ≥ 18 years
* Able to understand and follow the study protocol
* Willingness to attend facility-based exercise training.
Exclusion Criteria:
* Metastatic (Stage IV) breast cancer
* Morbid obesity (BMI \> 40 kg/m²)
* Uncontrolled hypertension (systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 99 mmHg)
* Presence of implantable medical devices (e.g., pacemakers, nerve stimulators)
* Presence of metallic surgical implants (e.g., total hip or knee replacements) that interfere with assessment devices
* Contraindications for resistance training (e.g., acute infectious disease, severe cardiac disease, severe respiratory insufficiency)
* Concurrent malignant diseases
* Current participation in intense systematic exercise training (defined as at least 1 hour, twice per week)
* Previous participation in an exercise intervention clinical trial.
Primary outcome measure(s)
Change from Baseline in Skeletal Muscle Mass Index (SMI) — 16 weeks Skeletal Muscle Mass Index (SMI) is calculated by dividing total skeletal muscle mass (kg), as measured by bioelectrical impedance analysis (ACCUNIQ BC720; SELVAS Healthcare), by the square of the height (m²). Higher scores indicate greater muscle mass relative to height (better outcome).
Trial sites (1)
Facility
City
Region
Status
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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