Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly

Condition(s) studied

Investigational drug(s) / intervention(s)

Animal-Based Oil Group: Participants in animal-based oil group will follow a diet in which the primary fat source is animal-based oil. The diet will supplement for 12 weeks.

Plant-Based Oil Group: Participants in plant-based oil group will follow a diet in which the primary fat source is plant-based oil. The diet will supplement for 12 weeks.

Study summary

Population aging has become a significant global concern, and Taiwan is set to officially enter the "super-aged society" in 2025. As individuals age, various physiological functions gradually decline, including a reduction in muscle mass, which is a key aspect of the aging process.

This interventional study aims to investigate the effects of leucine-rich protein combined with polyunsaturated fatty acid supplementation on middle-aged and elderly individuals (aged 50 and above) who are at high risk for sarcopenia.

Eligibility

Primary outcome measure(s)

• muscle mass — baseline, 12 weeks
  Utilize Bioelectrical Impedance Analysis (BIA) to measure the Appendicular Skeletal Muscle Mass Index Level (ASMI) (kg/m\^2)
• muscle function — baseline, 12 weeks
  utilize handgrip dynamometer to measure the hand grip strength (kg).
• physical function — baseline, 12 weeks
  To assess the participant's walking speed over a 4-meter distance.

Trial sites (1)

More Chang Gung Memorial Hospital trials in Taiwan

Other trials for the same condition