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Clinical Trials in Italy / NCT07214753
Recruiting Observational

A Real-life Observational Study in Severe Eosinophilic Asthma Adult Participant Treated With Benralizumab in Italy

NCT07214753 · tracked via the Priya Life Science Italy tracker
Phase
Observational
Started
2025-12-20
Last updated
2026-09-18

Condition(s) studied

Severe Eosinophilic Asthma

Investigational drug(s) / intervention(s)

benralizumab →

benralizumab: 30mg s.c. as per SmPC

Study summary

This is an observational, multicenter, prospective study on patients with severe eosinophilic asthma treated with benralizumab aimed at evaluating the achievement of partial and complete clinical remission.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Adults (≥ 18 years old) diagnosed with severe uncontrolled eosinophilic asthma. * Benralizumab has been prescribed according to the approved label and local reimbursement criteria * Provision of signed Informed Consent Form (ICF) prior to any study-related activities * Benralizumab has been initiated within 7 days prior to study enrollment or is planned to be initiated within 7 days after enrollment (in the latter case, provided that the decision to prescribe benralizumab is made prior to the decision to enroll the patient in the study). Exclusion Criteria: * Benralizumab treatment within the 12 months prior to study enrollment and up to 8 days before enrollment * Previous participation (in the 12 months before enrollment), current participation or plan to participate within the follow up period to any other clinical trial. * Contraindication to benralizumab as per current Summary of Product Characteristics (SmPC). * Pregnant or lactating women. * patients with any clinical condition that may interfere with the subject's ability to cooperate and comply with the study procedures based on the Investigator's judgement. * Previous or concomitant use of omalizumab, reslizumab, dupilumab, tezepelumab or mepolizumab without washout period as per clinical practice

Primary outcome measure(s)

Trial sites (28)

FacilityCityRegionStatus
Research Site Salerno Battipaglia Not Yet Recruiting
Research Site Padova Cittadella Not Yet Recruiting
Research Site Teramo Giulianova Recruiting
Research Site Treviso Montebelluna Recruiting
Research Site Varese Tradate Recruiting
Research Site Bari Italy Recruiting
Research Site Bergamo Italy Not Yet Recruiting
Research Site Bologna Italy Recruiting
Research Site Bologna Italy Not Yet Recruiting
Research Site Brescia Italy Not Yet Recruiting
Research Site Catania Italy Not Yet Recruiting
Research Site Catanzaro Italy Recruiting
Research Site Florence Italy Not Yet Recruiting
Research Site Foggia Italy Not Yet Recruiting
Research Site Messina Italy Not Yet Recruiting
Research Site Milan Italy Recruiting
Research Site Modena Italy Recruiting
Research Site Naples Italy Recruiting
Research Site Naples Italy Not Yet Recruiting
Research Site Padova Italy Not Yet Recruiting
Research Site Palermo Italy Recruiting
Research Site Pavia Italy Not Yet Recruiting
Research Site Roma Italy Not Yet Recruiting
Research Site Roma Italy Recruiting
Research Site Sassari Italy Not Yet Recruiting
Research Site Siena Italy Not Yet Recruiting
Research Site Torino Italy Recruiting
Research Site Verona Italy Not Yet Recruiting

On this site

📄 Fasenra (benralizumab) drug profile →

More AstraZeneca trials in Italy

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07214753 on ClinicalTrials.gov ↗ ← All trials in Italy