Ireland
--:--IST
Enrolling by invitation Observational

European Long-acting Antipsychotics in Schizophrenia Trial-II

NCT05165316 · tracked via the Priya Life Science Israel tracker
Sponsor
Rene Kahn
Phase
Observational
Started
2021-12-31
Last updated
2026-01-23

Condition(s) studied

Schizophrenia

Study summary

Schizophrenia is a chronic psychiatric illness with a heterogeneous disease course, varying from periods of symptomatic remission to relapse. Relative to the wealth of scientific data on the course of schizophrenia during the two years following the first psychotic episode, the outcome of schizophrenia patients over the first decade of their illness has been studied to a lesser degree. In this follow-up cohort study the aim is to investigate the long-term outcome of schizophrenia patients who participated in the previously conducted EULAST-I clinical trial, in the first decade after being diagnosed.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: 1. Capable of providing written informed consent / have a legal representative to provide written informed consent. \* 2. Having been randomized to one of the four treatment arms (aripiprazole oral, aripiprazole depot, paliperidone oral, paliperidone depot) in the 2014-002765-30 EULAST-I clinical trial or having participated in the EULAST-I naturalistic cohort study. * Unless prohibited by local law (e.g. due to incarceration). Exclusion Criteria: No exclusion criteria are applicable in this study.

Primary outcome measure(s)

  • To assess which baseline EULAST-I clinical trial baseline characteristics predict healthcare utilization (defined as number of days hospitalized) over a period of 3 - 10 years (since the EULAST-I clinical trial baseline visit). — 3 - 10 years (since the EULAST-I clinical trial baseline visit).

Trial sites (1)

FacilityCityRegionStatus
Tel Hashomer The Sheba Medical Center Ramat Gan Israel
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05165316 on ClinicalTrials.gov ↗ ← All trials in Israel