Ireland
--:--IST
Recruiting Not applicable

Acupuncture Mechanism in Relief of Gag Reflex

NCT07664826 · tracked via the Priya Life Science Germany tracker
Phase
Not applicable
Started
2026-01-21
Last updated
2026-06-24

Condition(s) studied

Gag (Pharyngeal) Reflex

Investigational drug(s) / intervention(s)

Acupuncture

Acupuncture: Needling of acupoints CV24, PC6 and K3

Study summary

The gag reflex relief effect of acupuncture of CV24 acupoint will be compared to acupuncture of PC6 and K3 acupoints in healthy volunteers in crossover mode. Second step will be the investigation whether local anesthesia using EMLA creme will block the gag relief effect of CV24 acupuncture in healthy volunteers.

Eligibility

Sex
ALL
Min age
20 Years
Max age
40 Years
Healthy volunteers
Accepted
Inclusion Criteria: 1. Healthy volunteers aged between 20-40 years old with an American Society of Anesthesiologists physical status of I to II naïve to acupuncture 2. Participants without previous opioid and psychotropic medication 3. Without use of recreational drugs 3 days prior to study sessions 4. Without systemic disease or local skin lesions at the sites of acupuncture 5. Without drug allergy to local anesthetics, especially EMLA preparation 6. Participants who have given written informed consent Exclusion Criteria: 1. Local skin infection at the sites of acupuncture 2. Aged \< 20 or \> 35 years 3. History of drug allergy to local anesthetics 4. Participants who are unable to understand the consent form or to use numeric rating scale NRS-11 Discontinuation Criteria 1. Any adverse effects during study session 2. In case of local or systemic infection 3. In case if subject will withdraw from participation in this study at any time, for any reason, specified or non-specified, and without penalty or loss of benefits

Primary outcome measure(s)

  • Length of saliva injector insertion (cm) — Day 1 ( before and after acupuncture)
    Saliva injector is inserted intraoral slowly until the gagging (pharyngeal reflex) is elicited; the length of insertion of saliva injector will be measured in centimeters

Trial sites (1)

FacilityCityRegionStatus
University Medicine of Greifswald Greifswald Germany Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07664826 on ClinicalTrials.gov ↗ ← All trials in Germany