Dresden Corneal Disease and Treatment Study

Condition(s) studied

Investigational drug(s) / intervention(s)

corneal cross-linking: UV-A Irradiation and riboflavin

corneal topography and tomography: Detailed Information about corneal tomography is used for diagnosis

Study summary

The purpose of this study is long-term follow up of patients with corneal diseases to analyze the quality of surgical interventions and diagnosis. Corneal ectasia, especially keratoconus, is a corneal disease that leads to an irreversible loss of visual acuity while the cornea becomes steeper, thinner and irregular. For these patients, surgical intervention (e.g. corneal cross-linking) is performed, in case of disease progression. Overall, a long-term follow up is needed to evaluate an early disease progression as well as corneal stability after surgical intervention.

Eligibility

Primary outcome measure(s)

• Follow-up intervals — 15 years
  To find the best follow-up intervals for keratoconus patients with or without progression of the disease
• postoperative follow-up intervals — 15 years
  To find the best follow-up intervals for keratoconus patients after surgical Intervention.

Trial sites (1)

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