Pilot Study Evaluating brainQuant's Ability to Detect Alterations in White Matter in Diffusion MRI, Indicative of Post-traumatic Lesions

Condition(s) studied

Study summary

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease described in boxing, but also in contact sports such as American football.

Soccer, due to repeated headers, could also be associated, albeit to a lesser degree, with the development of this type of pathology.

Indeed, it has been shown that playing soccer can be accompanied by cognitive impairments, and neurodegenerative brain abnormalities have been described in neuropathology studies of former professional soccer players. Subradiological brain abnormalities have been found in multimodal MRI in various sports. Similarly, a decrease in cognitive performance has been described.

The discovery of this type of anomaly in a population of professional footballers nearing the end of their careers could lead to:

* The implementation of appropriate monitoring for professional footballers through early detection of lesions via MRI and cognitive disorders
* The implementation of preventative measures for professional footballers, but also for amateur footballers from a very young age.

Eligibility

Primary outcome measure(s)

• Changes found in MRI diffusion tensor imaging of professional football players — day 1 post-consultation

Trial sites (1)

More University Hospital, Strasbourg, France trials in France