Incidence and severity of postoperative delirium associated with Dexmedetomidine sedation during femur osteosynthesis in the elderly population

Condition studied

Postoperative delirium

Investigational medicinal product(s)

Every trial of Propofol and Dexmedetomidine across our registers →

Eligibility

Primary endpoint

Prevalence, severity, and course of delirium during the postoperative period.

Endpoint detail

Clinical and epidemiological data, including factors associated with the onset of postoperative delirium., Sedative medications and administered doses, degree and quality of sedation as measured by the RASS scale (Appendix 1), events during sedation (episodes of agitation, need for restraint, etc.), and depth of sedation (BIS)., Clinical parameters (BP, SpO₂, HR, EtCO₂), basic laboratory tests (hemoglobin, electrolytes, blood glucose, and inflammatory markers such as CRP), and intra- and postoperative events (bleeding, blood product transfusion, hypertension/hypotension, desaturation, apnea, etc.)., Pain assessment (PA) and analgesia administered during the perioperative and postoperative periods.