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Clinical Trials in China / NCT07060625
Enrolling by invitation Observational

The Effect of Semi-recumbent Position on Hypoxemia After Lung Segment/Lobe Surgery

NCT07060625 · tracked via the Priya Life Science China tracker
Sponsor
Shanghai Pulmonary Hospital, Shanghai, China
Phase
Observational
Started
2024-12-23
Last updated
2025-07-11

Condition(s) studied

Lung Cancer (Diagnosis)Hypoxemia

Investigational drug(s) / intervention(s)

Semi-reclining position

Semi-reclining position: During anesthesia recovery, the patient's position should be in a semi-recumbent position

Study summary

Thoracoscopic surgery is the most common surgical approach in thoracic surgery, which reduces surgical trauma and postoperative pain compared with open thoracotomy, but postoperative complications should not be overlooked, with hypoxemia being particularly prominent. Postoperative hypoxemia is highly prevalent among patients recovering from non-cardiac surgery, accounting for over one-third of all cases. Hypoxemia impairs wound healing and leads to other severe complications such as cerebral dysfunction, arrhythmia, and myocardial ischemia, all of which adversely affect postoperative recovery. Although oxygen therapy can prevent and treat hypoxemia, many patients still experience hypoxia in the post-anesthesia care unit (PACU). Numerous studies have investigated various ventilation techniques aimed at enhancing postoperative pulmonary function, but the benefits of protective ventilation strategies may be lost during emergence from anesthesia. Several other studies also indicate that intraoperative ventilation measures do not improve postoperative pulmonary function. The lack of evidence demonstrating the efficacy of oxygen therapy or protective ventilation techniques in treating postoperative hypoxemia underscores the need to explore alternative strategies. Patient positioning during emergence from anesthesia is associated with perioperative and postoperative complications. Although no consensus exists on the optimal patient position during emergence, the supine position is often favored by anesthesiologists due to its simplicity and ease of monitoring. However, the reduced functional residual capacity associated with the supine position tends to promote airway closure and diminish gas exchange.

Eligibility

Sex
ALL
Min age
18 Years
Max age
85 Years
Healthy volunteers
No
Inclusion Criteria: * Age 18-85 years old; Undergo thoracoscopic segment/lobectomy; American Society of Anesthesiologists (ASA) grade 1\~3 Exclusion Criteria: * Patients with mental or cognitive dysfunction who cannot communicate normally; Patients with tracheal catheters retained in ICU; Patients with cervical spondylosis, ankylosing spondylitis and other patients who cannot lift their upper body; Patients who have participated in other clinical trials; Patients who refuse to sign informed consent; Patients who have had chest surgery in the past.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Shanghai Pulmonary Hospital Shanghai Shanghai Municipality

More Shanghai Pulmonary Hospital, Shanghai, China trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07060625 on ClinicalTrials.gov ↗ ← All trials in China