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Clinical Trials in China / NCT06712511
Recruiting Not applicable

The Effect of Coffee on Energy Expenditure and Caffeine Metabolism

NCT06712511 · tracked via the Priya Life Science China tracker
Sponsor
Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Phase
Not applicable
Started
2024-10-23
Last updated
2025-03-27

Condition(s) studied

Healthy

Investigational drug(s) / intervention(s)

Caffeine content

Caffeine content: Participants will drink the same volume of water or coffee, caffeine content is 2mg/kg by body weight.

Study summary

Obesity is a risk factor for chronic diseases, and improving energy expenditure is a way to prevent and treat obesity. The purpose of this project is to explore the relationship between the effect of coffee on energy expenditure and caffeine metabolism, which has important significance in the rational application of caffeine.

Eligibility

Sex
ALL
Min age
18 Years
Max age
40 Years
Healthy volunteers
Accepted
Inclusion Criteria： * Healthy adults. * Must be able to drink coffee. Exclusion Criteria: * Diabetes. * Hypoglycemia. * Gout. * Osteoporosis. * Gastric ulcer. * Pancreatitis. * Intestinal obstruction. * Blood phobia. * Pathological hypo or hyper tension. * Impaired glucose tolerance. * Claustrophobia. * HIV,etc.

Primary outcome measure(s)

  • Total energy expenditure — 2 days
    Total energy expenditure will be measured by Chamber (OMNICAL).
  • The concentration of caffeine and its metabolites in urine — 2 days
    The contents of caffeine and it's metabolites will be measured by gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS ).
  • The concentration of caffeine and its metabolites in serum — 1 day
    The concentration of caffeine and its metabolites in serum will be measured by gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS ).

Trial sites (1)

FacilityCityRegionStatus
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences Shenzhen Guangdong Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06712511 on ClinicalTrials.gov ↗ ← All trials in China