Maternal Grandmothers in the Born in Guangzhou Cohort Study
Condition(s) studied
Study summary
The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology and on explaining the cause of the disease from the perspective of "grandmother-mother-child" heredity. Data are collected regarding environmental exposures, lifestyle, and social support on grandmother from birth to old age. Biological samples including blood and tissue samples are collected.
Eligibility
Primary outcome measure(s)
- Haplotypes transfered by non-inherited maternal antigens from maternal grandmother to female offspring — From the date of her daughter get pregnant until the date her grandchild/grandchildren is/are given birth
Assessed by analyses of MHC haplotypes, HLA haplotypes, and levels of non-inherited maternal antigens of mother and offspring, and pregnancy complication of maternal grandmothers and mothers
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Guangzhou Women and Children's Medical Center | Guangzhou | Guangdong | Recruiting |
More Guangzhou Women and Children's Medical Center trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT03633162 on ClinicalTrials.gov ↗ ← All trials in China