Clinical Trials in China / NCT03398629
Recruiting
Observational
Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies
NCT03398629 · tracked via the Priya Life Science China tracker
Condition(s) studied
Intrauterine Growth RestrictionFetal AnomalyChromosomal AnomaliesPregnancy
Study summary
The purpose of this prospective cohort study is to build a large platform that includes clinical information (prenatal diagnosis and postnatal follow-up data) and biological specimen banks of fetuses/infants with IUGR or congenital anomalies, which provide vital support and research foundation for accurate diagnosis, precision treatment and meticulous management.
Eligibility
Inclusion Criteria:
All pregnant women who present to Guangzhou Women and Children's Medical Center meeting one of the following prenatal diagnoses and neonates/infants who are diagnosed as one of the following anomalies will be invited to participate:
1. Intrauterine growth restriction (IUGR)
2. Structural anomaly
3. Chromosomal anomaly
Exclusion Criteria:
1. Pregnant women who don't agree to participate;
2. Pregnant women delivering babies at other hospitals.
3. Prenatally suspected anomalies that are not confirmed by postnatal diagnosis.
Primary outcome measure(s)
- Consistency between prenatal and postnatal diagnosis of fetal anomalies — At delivery
Comparison of results of prenatal ultrasound or genetic amniocentesis and results of postnatal diagnosis in neonates with anomalies. - Constituent ratio of all types of anomalies among live infants — At delivery
Including constituent ratio of all types of anomalies in prenatal diagnosis and constituent ratio of anomalies confirmed by clinical diagnosis after births. - Differences of mortality rates between infants with prenatal diagnosis and those with postnatal diagnosis — up to 1 year
- Differences of Kaup's indexes between IUGR infants with prenatal intervention and those with postnatal intervention — up to 1 year
Kaup's index＝weight(kg)÷height(cm)\^2×10\^4 - Recovery of organ functions following postnatal management in infants with anomalies — up to 5 years
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Guangzhou Women and Children's Medical Center | Guangzhou | Guangdong | Recruiting |
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT03398629 on ClinicalTrials.gov ↗ ← All trials in China