Sponsor · clinical trials

Istituto Ortopedico Rizzoli clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our Italy register with Istituto Ortopedico Rizzoli as lead sponsor. Synced 12 Nov 2026

108Current trials

92Recruiting now

5Drugs in these trials

1Trial register

Maintained by Sreepriya Prasannan

MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany

Compiled from ClinicalTrials.gov and CTIS registry records · Synced 12 Nov 2026 · Editorial standards

At a glance

Istituto Ortopedico Rizzoli is the lead sponsor of 108 current clinical trials in our Italy register. 92 are recruiting patients now. The most common phase is Observational. The drugs named most often in its trials are Bleomycin, Bone marrow aspirate and Leukocyte-Poor Platelet-Rich Plasma. The most-studied condition is Knee Osteoarthritis.

ClinicalTrials.gov trials by status

Recruiting9285%
Not yet open44%
Active, closed98%
By invitation33%

Trials by phase

Observational5450%
Not applicable5349%
Phase 211%

Clinical trials sponsored by Istituto Ortopedico Rizzoli

108 on ClinicalTrials.gov

Study	Phase	Status	Start	Registers
Functional and Morphological Characterization of Multiple Osteochondromas Disorder NCT06703736 · ClinicalTrials.gov ↗ · Hereditary Multiple Osteochondromas	Observational	Recruiting	2025-05	Italy
Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis NCT04998188 · ClinicalTrials.gov ↗ · Knee Osteoarthritis	Not applicable	Recruiting	2022-02	Italy
PRP Versus HA IN OSTEOARTHRITIS OF THE PATELLOFEMORAL JOINT NCT04937998 · ClinicalTrials.gov ↗ · Patellofemoral Osteoarthritis	Not applicable	Recruiting	2022-10	Italy
Inter- and Intra-Observer Reliability of the Iowa Level of Assistance Scale and the Effect of Staff Retraining NCT07330011 · ClinicalTrials.gov ↗ · Joint Replacement, Functional Recovery, Reliability	Observational	Recruiting	2025-11	Italy
Fibrous Dysplasia: An Epidemiological and Correlational Evaluation of Multimodal Data NCT07569731 · ClinicalTrials.gov ↗ · Fibrous Dysplasia, Fibrous Dysplasia of Bone, Fibrous Dysplasia/McCune-Albright Syndrome	Observational	Recruiting	2022-05	Italy
Clinical and Radiological Results of Long Term Tibial and Femoral Osteotomy in Knee Ostheoarthritis With Concomitant Lower Limb Malalignement NCT06462625 · ClinicalTrials.gov ↗ · Knee Osteoarthritis, Malalignment, Bone	Observational	Recruiting	2023-01	Italy
Homologous PRP vs Placebo in Knee Osteoarthritis in Over 65 Years Old Patients NCT04901273 · ClinicalTrials.gov ↗ · Knee Osteoarthritis	Not applicable	Recruiting	2021-12	Italy
Crosscultural Adaptation And Validation Of The Italian Version Of The New Knee Society Knee Scoring System NCT06726629 · ClinicalTrials.gov ↗ · Knee Osteoarthritis	Observational	Recruiting	2024-11	Italy
Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery NCT05779670 · ClinicalTrials.gov ↗ · Osteosarcoma, Ewing Sarcoma, Chondrosarcoma	Observational	Recruiting	2023-01	Italy
Effectiveness of Telerehabilitation in Continuity With Outpatient Physiotherapy After Total Hip Replacement. NCT06238960 · ClinicalTrials.gov ↗ · Total Hip Replacement, Telerehabilitation, Physiotherapy	Not applicable	Recruiting	2024-02	Italy
Global collaboRAtion on CIC-DUX4, BCOR-CCN3, High-grade Undifferentiated Round Cell Sarcoma (URCS) Project NCT05357768 · ClinicalTrials.gov ↗ · Undifferentiated Round Cell Sarcoma	Observational	Recruiting	2019-06	Italy
Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse NCT04758000 · ClinicalTrials.gov ↗ · Osteosarcoma, Ewing Sarcoma Drug: Metformin Hydrochloride	Phase 2	Recruiting	2021-03	Italy
Effectiveness of Telerehabilitation as an Alternative to Outpatient Physiotherapy in the 1 Month After Arthroscopic Rotator Cuff Repair Surgery NCT06744218 · ClinicalTrials.gov ↗ · Rotator Cuff Injuries	Not applicable	Recruiting	2024-11	Italy
Acellular Matrix From Human Dermis in Combination With Orthobiologic Stimuli for Augmentation of Massive Rotator Cuff Tears NCT05855759 · ClinicalTrials.gov ↗ · Rotator Cuff Tears	Not applicable	Recruiting	2023-12	Italy
Comparison Between the Use of the Tensioner and Standard Surgical Technique for Ligament Balancing of Total Knee Prostheses NCT06770153 · ClinicalTrials.gov ↗ · Knee Injuries	Not applicable	Recruiting	2024-10	Italy
Total Knee Arthroplasty: Fast Track Protocol is the Future? NCT03869996 · ClinicalTrials.gov ↗ · Osteoarthritis, Knee, Arthropathy of Knee	Not applicable	Recruiting	2019-02	Italy
Study of Infantile Lower Limb Malformations and Deformities NCT06519175 · ClinicalTrials.gov ↗ · Deformity of Limb	Observational	Recruiting	2024-10	Italy
Radiomics Compared With Conventional Response Criteria for Predicting Progression of Desmoid Tumor After Cryoablation NCT06224283 · ClinicalTrials.gov ↗ · Desmoid	Observational	Recruiting	2024-02	Italy
Use of Leukocyte-Rich PRP or Leukocyte-Free PRP in the Treatment of Hip Osteoarthritis NCT05497349 · ClinicalTrials.gov ↗ · Hip Osteoarthritis	Not applicable	Recruiting	2022-10	Italy
Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta NCT07287241 · ClinicalTrials.gov ↗ · Osteogenesis Imperfecta (OI), Osteogenesis Imperfecta	Observational	Recruiting	2025-06	Italy
Early Postoperative Pain Following a Limb Amputation NCT07393139 · ClinicalTrials.gov ↗ · Amputation, Surgical, Pain Management, Rehabilitation	Observational	Recruiting	2026-01	Italy
Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint NCT06462040 · ClinicalTrials.gov ↗ · Osteochondral Defect, Osteochondritis Dissecans, Osteochondral Fracture	Observational	Recruiting	2024-09	Italy
Knee Osteotomy Associated With Allograft Meniscus Transplantation NCT05840887 · Malalignment, Bone, Osteoarthritis, Knee	Not applicable	Recruiting	2023-08	Italy
Which Markers of Musculoskeletal Health Can Explain Complications in Spinal Surgery? NCT06736106 · ClinicalTrials.gov ↗ · Spine Injuries and Disorders	Not applicable	Recruiting	2024-09	Italy
Archive of Custom-made Guides for Orthopedic Surgery NCT07893132 · ClinicalTrials.gov ↗ · Deformity of Bone	Observational	Recruiting	2025-02	Italy
Treatment of Symptomatic Bilateral Knee Osteoarthritis: Intra-articular Injection of Autologous Microfragmented Adipose Tissue and Hyaluronic Acid vs Intra Articular Injection of Autologous Microfragmented Adipose Tissue NCT07121556 · ClinicalTrials.gov ↗ · Osteoarthritis Knees Both	Not applicable	Recruiting	2025-09	Italy
Multifactorial Strategies for the Prevention of the Risks of Ulceration in Patients Affected by Diabetic Foot (DARE-DiaFoot) NCT07021222 · ClinicalTrials.gov ↗ · Diabetes Mellitus Foot Ulcer	Not applicable	Recruiting	2025-11	Italy
Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients NCT06483269 · ClinicalTrials.gov ↗ · Knee Osteoarthritis	Not applicable	Recruiting	2023-10	Italy
Early MOtion Total Ankle Artroplasty NCT06525545 · ClinicalTrials.gov ↗ · Ankle Osteoarthritis, Ankle - Recurrent Dislocation, Cartilage Disease	Not applicable	Recruiting	2023-10	Italy
Validation of the Italian Version of the Forgotten Joint Score (FJS-12) in Total Ankle Replacement NCT06091397 · ClinicalTrials.gov ↗ · PROMs, Total Ankle Replacement, Italian Forgotten Joint Score	Observational	Recruiting	2022-07	Italy
Advanced Surgical Simulation Processes in the Correction of Skeletal Defects and Deformities NCT06380530 · ClinicalTrials.gov ↗ · Musculoskeletal Deformity, Musculoskeletal Abnormalities, Musculoskeletal Disorder	Not applicable	Recruiting	2024-10	Italy
Evaluation of the Clinical Outcomes of the Total Knee ps Prosthesis Implanted With the Use of Inertial Sensors NCT06321042 · ClinicalTrials.gov ↗ · Prosthesis Durability	Observational	Recruiting	2023-01	Italy
Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design NCT06309433 · Periprosthetic Osteolysis	Not applicable	Recruiting	2023-08	Italy
Clinical and Radiological Evaluation Over 10 Years After Bilateral Subtalar Arthrorisis Surgery With Endorthesis and Calcaneal Stop for the Correction of Pediatric Flatfoot NCT07569835 · ClinicalTrials.gov ↗ · Flat Foot Acquired Bilateral (Pes Planus)	Observational	Recruiting	2024-05	Italy
Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA NCT06611618 · ClinicalTrials.gov ↗ · Knee Osteoarthritis (Knee OA), Falls Prevention	Not applicable	Recruiting	2025-01	Italy
Retrospective and Prospective Evaluation of Hip Short Stem Performed by Anterior Approach NCT07600632 · ClinicalTrials.gov ↗ · Hip Arthritis	Observational	Recruiting	2025-09	Italy
"Transarterial Microembolization (TAME) in Inflammatory Knee Pathology" NCT07140367 · ClinicalTrials.gov ↗ · Inflammatory Articular Diseases, Knee Osteoarthristis	Observational	Recruiting	2025-09	Italy
Compliance With PROMs Detection Through Digital Support and Correlation Compared to Standard Outpatient PROMs Detection in Hip Prosthetics (DIG-PROMs-h) NCT04749511 · ClinicalTrials.gov ↗ · Quality of Life	Not applicable	Recruiting	2020-11	Italy
Treatment of Desmoid Fibromatosis With Arterial Embolization NCT06945887 · ClinicalTrials.gov ↗ · Desmoid Fibromatosis	Observational	Recruiting	2025-07	Italy
Intraoperative Laxity Assessment of ACL Reconstruction, ACL Revision and MAT NCT03441165 · ClinicalTrials.gov ↗ · Intraoperative Musculoskeletal Injury	Observational	Recruiting	2018-02	Italy
Biomechanical Functional Evaluation of Plantar Pressures After Foot and Ankle Surgeries NCT06090357 · ClinicalTrials.gov ↗ · Plantar Pressure	Not applicable	Recruiting	2021-07	Italy
Development and Pre-validation of a Machine Learning-based Prediction Algorithm for Early Functional Recovery in Patients Undergoing Hip and Knee Replacement Surgery NCT07333560 · ClinicalTrials.gov ↗ · Artificial Intelligence (AI), Machine Learning, Joint Replacement	Observational	Recruiting	2026-03	Italy
Clinical and Instrumental Assessment of Meniscal ROOT Tears Treated Through Suture to the Posterior Cruciate Ligament NCT06507241 · ClinicalTrials.gov ↗ · Meniscus Tear, Meniscus Lesion, Knee Injuries	Observational	Recruiting	2024-10	Italy
De Quervain's Disease in the Acute Phase:a Study Aimed at Evaluating the Effectiveness of Standard Physiotherapy Treatment (HANDGUIDE), Compared to Experimental Treatment After Performing Ultrasound-guided Infiltrative Therapy. NCT06296472 · ClinicalTrials.gov ↗ · De Quervain Disease, Hand Tenosynovitis	Not applicable	Recruiting	2024-02	Italy
Long Term Evaluation of Clinical and Radiologic Results on Femoro-patellar Joint After High Tibial Osteotomy NCT06251752 · ClinicalTrials.gov ↗ · Knee Osteoarthritis, Deformity Knee	Not applicable	Recruiting	2020-10	Italy
Peripheral Mononuclear Cells to Screen, Monitor and Stratify the Population at Risk of Osteoporosis and Fractures NCT06551155 · ClinicalTrials.gov ↗ · Osteoporosis, Osteopenia, Osteoporosis Fracture	Observational	Recruiting	2024-08	Italy
Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN) NCT06527664 · ClinicalTrials.gov ↗ · Bone Loss, Hip Prosthesis Infection, Arthroplasty Complications	Observational	Recruiting	2024-10	Italy
Bone Marrow Versus Adipose Tissue as a Cell Source for Infiltrative Treatment of Knee Osteoarthritis NCT06040957 · ClinicalTrials.gov ↗ · Knee Osteoarthritis Drug: Bone marrow aspirate	Not applicable	Recruiting	2024-01	Italy
Correlation Between Deficits in Knee ROM Recovery and Difficulty in Dorsiflexing the Tibio-tarsal Joint in Patients Undergoing Total Knee Replacement Surgery. NCT07016243 · ClinicalTrials.gov ↗ · Articulation Disorders	Observational	Recruiting	2025-04	Italy
Periprosthetic Joint Infections: Diagnostic Accuracy and Cost-effectiveness Analysis of Serum and Synovial Markers NCT04858217 · ClinicalTrials.gov ↗ · Prosthetic Joint Infection	Observational	Recruiting	2022-02	Italy
Functional Instability in Patients Suffering From Collagen Disease and Joint Hypermobility NCT05871216 · ClinicalTrials.gov ↗ · Hypermobility Syndrome, Danlos Disease, Ehlers, Collagen Diseases	Observational	Recruiting	2020-10	Italy
Efficacy of New Silver-coated Prosthesis in Reducing the Incidence of Periprosthetic Infections NCT06887816 · ClinicalTrials.gov ↗ · Hip Infection	Observational	Recruiting	2025-03	Italy
Pilot Study of Percutaneous Correction of Hallux Valgus NCT05880407 · ClinicalTrials.gov ↗ · Hallux Valgus	Not applicable	Recruiting	2022-02	Italy
Outcomes of Surgical Treatment Using a Custom-made Device for Total Ankle and Talar Replacement in the Management of Severe Cases of Bone Loss or Bone Compromise: a Pilot Study. NCT07569848 · ClinicalTrials.gov ↗ · Arthrosis, Ankle Arthritis, Ankle Replacement	Observational	Recruiting	2022-02	Italy
Calibr-Ì: Comparative Evaluation of Phantomless Calibration Methods to Quantify Bone Mineral Density for Opportunistic Analysis of CT Scans NCT06454617 · ClinicalTrials.gov ↗ · Osteoporosis	Observational	Recruiting	2024-06	Italy
Clinical Validation of BBCT-hip NCT06270758 · ClinicalTrials.gov ↗ · Osteoporosis	Observational	Recruiting	2023-11	Italy
Compliance With PROMs Detection Through Digital Support and Correlation Compared Standard to Outpatient Detection in Knee Prosthetics NCT04752761 · ClinicalTrials.gov ↗ · Approach-Approach Conflict, Knee Discomfort	Not applicable	Recruiting	2020-11	Italy
Virtual Reality for Anxiety in Interventional Radiology Procedures NCT06745765 · ClinicalTrials.gov ↗ · Preoperative Anxiety	Not applicable	Recruiting	2024-11	Italy
An Observational Study of Local Relapse After High Grade Osteosarcoma NCT06017518 · ClinicalTrials.gov ↗ · Osteosarcoma	Observational	Recruiting	2022-06	Italy
Leukocyte-rich PRP or Leukocyte-free PRP vs Placebo in the Treatment of Epicondylitis NCT06040203 · ClinicalTrials.gov ↗ · Tennis Elbow Drugs: Leukocyte-Poor Platelet-Rich Plasma, Lr-Prp	Not applicable	Recruiting	2023-03	Italy
Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma NCT06243588 · ClinicalTrials.gov ↗ · Ewing Sarcoma	Observational	Recruiting	2024-01	Italy
Virtual Reality for Reducing Anxiety in Pediatric Orthopedic Surgery NCT06604364 · ClinicalTrials.gov ↗ · Virtual Reality	Not applicable	Recruiting	2024-06	Italy
Evaluation of Clinical-functional and Radiographic Outcomes in Patients Who Underwent Meniscal Allograft Transplantation (MAT) at 10 Years. NCT06522152 · ClinicalTrials.gov ↗ · Meniscus Disorder, Arthritis Knee	Observational	Recruiting	2024-10	Italy
Registry of Li Fraumeni and Li Fraumeni Like Syndromes NCT04982744 · ClinicalTrials.gov ↗ · Li-Fraumeni Syndrome, Li-Fraumeni-Like Syndrome	Observational	Recruiting	2020-07	Italy
Evaluation of 5-year Survival and Clinical Outcomes in Patients Undergoing Total Knee Arthroplasty With a Polyethylene Tibial Component NCT07544264 · ClinicalTrials.gov ↗ · Prosthesis Survival, Arthropathy of Knee	Not applicable	Recruiting	2026-05	Italy
Study of Parameters of Osteosarcopenia in Patients With Hip Fracture NCT04730622 · ClinicalTrials.gov ↗ · Osteoporotic Fracture of Femur, Osteoarthritis, Hip	Observational	Recruiting	2020-11	Italy
Arthrorisis of the Subtalar Joint With a Polymeric Endorthesis for Flexible Flatfoot Treatment During the Growth Age Prospective Evaluation NCT06091371 · ClinicalTrials.gov ↗ · Subtalar Arthrorisis, Flat Feet, Growth Age	Observational	Recruiting	2022-07	Italy
Use of Reconstructive Microsurgery for the Treatment of Lymphedema NCT07889856 · ClinicalTrials.gov ↗ · Lymphedema	Observational	Recruiting	2026-09	Italy
Descriptive Analysis of Surgeries in Patients With Multiple Osteochondromas NCT07556874 · ClinicalTrials.gov ↗ · Multiple Osteochondroma	Observational	Recruiting	2025-10	Italy
Innovative Drug Delivery Nanophotonic Platform for Implementation of Sarcoma Therapy NCT06599957 · ClinicalTrials.gov ↗ · Bone and Soft Tissue Tumors	Observational	Recruiting	2024-08	Italy
Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors NCT07112989 · ClinicalTrials.gov ↗ · Bone and Soft Tissue Tumors, Bone Metastases From Solid Tumors, Lung Metastases	Observational	Recruiting	2024-09	Italy
Minimally Invasive Surgery vs Standard Posterior Approach in the Treatment of Developmental Idiopathic Scoliosis NCT05860673 · ClinicalTrials.gov ↗ · Adolescent Idiopathic Scoliosis	Not applicable	Recruiting	2023-07	Italy
Identification of Circulating Biomarkers Associated With Extracellular Vesicles in Sarcomas NCT07685405 · ClinicalTrials.gov ↗ · Sarcoma, Ewing	Observational	Recruiting	2026-04	Italy
Comparison of Custom and Standard Total Knee Replacements NCT06122727 · ClinicalTrials.gov ↗ · Knee Osteoarthritis	Not applicable	Recruiting	2023-03	Italy
Comparison of Customized and Standard Total Ankle Prostheses NCT06193057 · ClinicalTrials.gov ↗ · Ankle Osteoarthritis	Not applicable	Recruiting	2023-07	Italy
Carbofix Pedicle Screw System: Evaluation of the Clinical and Radiographic Outcomes of the Use of a Carbon Fiber Device Compared to Titanium Devices in Patients Undergoing Spinal Arthrodesis for Degenerative Spinal Diseases NCT06209684 · ClinicalTrials.gov ↗ · Degenerative Disc Disease	Not applicable	Recruiting	2022-04	Italy
Triphasic Osteochondral Scaffold for the Treatment of the OCD of the Knee: Observational Study NCT05332288 · ClinicalTrials.gov ↗ · Osteochondritis Dissecans Knee	Observational	Recruiting	2022-04	Italy
Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho) NCT06119542 · ClinicalTrials.gov ↗ · Spinal Fusion	Observational	Recruiting	2026-02	Italy
CAS vs Standard Technique in TKA: Comparison of Clinical and Functional Results NCT06608745 · ClinicalTrials.gov ↗ · Knee Arthroplasty, Total	Not applicable	Recruiting	2024-02	Italy
FAldini Sport Total Joint Arthroplasty-Knee II NCT06383936 · ClinicalTrials.gov ↗ · Knee Osteoarthritis	Not applicable	Recruiting	2025-04	Italy
Combined Use of PRP and Hyaluronic Acid for Infiltrative Treatment of Patients With Knee Osteoarthritis NCT06685120 · ClinicalTrials.gov ↗ · Osteo Arthritis Knee	Not applicable	Recruiting	2025-12	Italy
Analysis of the Pathophysiological and Functional State of the Knee Joint NCT06490770 · ClinicalTrials.gov ↗ · Osteoarthritis, Knee, Cartilage Degeneration	Not applicable	Recruiting	2025-07	Italy
Arterial Embolization for the Treatment of Bone Metastases: Prospective Observational Study NCT06189079 · ClinicalTrials.gov ↗ · Bone Metastases	Observational	Recruiting	2023-05	Italy
Arterial Chemoembolization for the Treatment of Desmoid Fibromatosis NCT06268457 · ClinicalTrials.gov ↗ · Desmoid	Observational	Recruiting	2024-02	Italy
Legs Dysmetria in Total Hip Replacement: Does Hip Approacches and Navigation Decrease the Risk? NCT06506201 · ClinicalTrials.gov ↗ · Hip Osteoarthritis	Not applicable	Recruiting	2024-05	Italy
Clinical-MRI Evaluation in Patients Undergoing Subtalar Arthrorisis With Reabsorbable Endorthesis Implant in PLLA NCT06525532 · ClinicalTrials.gov ↗ · Lower Limb Deformity	Observational	Recruiting	2024-06	Italy
Bone Metastases Database of Patients Treated Surgically for Impending or Pathologic Fracture of Long Bones NCT03416959 · ClinicalTrials.gov ↗ · Neoplasm Metastasis	Observational	Recruiting	2018-01	Italy
Evaluation of Clinical and Radiographic Findings in Patients Treated Surgically for Biceps Long Head Injury NCT06483256 · ClinicalTrials.gov ↗ · Bicep Tendon Rupture	Not applicable	Recruiting	2024-11	Italy
Clinical and Functional Assessment of Patients With Transfemoral Amputation Treated With Osteointegrated Implant NCT06737770 · ClinicalTrials.gov ↗ · Prosthesis, Lower Limb Amputation Knee, Amputation; Traumatic, Leg, Lower	Not applicable	Recruiting	2025-01	Italy
Cryotherapy in the Treatment of Desmoid Tumors NCT05091255 · ClinicalTrials.gov ↗ · Desmoid	Not applicable	Recruiting	2021-05	Italy
Evaluation of the Osteointegrative and Regenerative Capacity of a Scaffold Enriched With Bone Marrow-Derived Cells at the Subchondral Level, Associated With Retrograde Drilling NCT07555899 · ClinicalTrials.gov ↗ · Osteochondral Lesion	Not applicable	Recruiting	2026-01	Italy
Treatment of Low-flow Venous Malformations With Electrosclerotherapy. Prospective Observational Study NCT06189092 · ClinicalTrials.gov ↗ · Vascular Malformations Drug: Bleomycin	Observational	Recruiting	2023-10	Italy
The Corrective Power of Subtalar Arthrodesis With Mini/Medial Bone Block (SAMBB) in Patients Affected by Progressive Collapsing Foot Deformity (PCFD): Analysis Using Weight-bearing Cone Beam CT. NCT07515170 · ClinicalTrials.gov ↗ · Flat Foot	Not applicable	Not yet open	2026-11	Italy
The Effectiveness of High-intensity Laser Therapy on Post-surgical Rehabilitation After Total Knee Arthroplasty NCT07568262 · ClinicalTrials.gov ↗ · Arthroplasty Complications, Pain, Postoperative	Not applicable	Not yet open	2026-09	Italy
Arthroscopic Treatment of Acetabular Labral Lesions: Intrarticular Injection of Bone Marrow vs Hip Arthroscopy Alone NCT07422662 · ClinicalTrials.gov ↗ · FemoroAcetabular Impingement	Not applicable	Not yet open	2026-09	Italy
The Effectiveness of High-intensity Laser Therapy After Arthroscopic Shoulder Rotator Cuff Repair. NCT07568288 · ClinicalTrials.gov ↗ · Rotator Cuff Tears	Not applicable	Not yet open	2026-09	Italy
Customized Bone Allografts by 3D-printing NCT05700526 · ClinicalTrials.gov ↗ · Musculoskeletal Deformity, Musculoskeletal Diseases, Musculoskeletal Disorder	Not applicable	By invitation	2022-06	Italy
Evaluation of Return to Sports Activity After Periacetabular Osteotomy: An Observational Study NCT07590882 · ClinicalTrials.gov ↗ · Hip Surgeries, Hip Developmental Dysplasia	Observational	By invitation	2025-11	Italy
A Retrospective and Prospective Study: Monocompartimental Knee Arthroplasty Combined With Anterior Cruciate Ligament Reconstruction Surgery - a Pilot Study NCT07377669 · ClinicalTrials.gov ↗ · Knee Arthritis Osteoarthritis, Cruciate Ligament Rupture	Observational	By invitation	2025-06	Italy
Incisional Biopsy Versus Core-needle Biopsy in Bone Tumors Analysis NCT07113301 · ClinicalTrials.gov ↗ · Malignant Bone Tumor	Observational	Active, closed	2024-11	Italy

Showing the 100 most recently updated of 108 trials (recruiting first). The rest are in the country registers linked in each row.

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

Drugs in Istituto Ortopedico Rizzoli trials

5 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

Bleomycin1 Bone marrow aspirate1 Leukocyte-Poor Platelet-Rich Plasma1 Lr-Prp1 Metformin Hydrochloride1

Conditions in Istituto Ortopedico Rizzoli trials

144 conditions

Knee Osteoarthritis9 Osteosarcoma3 Ewing Sarcoma3 Osteoarthritis, Knee3Desmoid3Osteoporosis3Joint Replacement2Malalignment, Bone2Chondrosarcoma2Rotator Cuff Tears2Knee Injuries2Arthropathy of Knee2Arthroplasty Complications2Hip Osteoarthritis2Adolescent Idiopathic Scoliosis2Ankle Osteoarthritis2Musculoskeletal Deformity2Musculoskeletal Disorder2Bone and Soft Tissue Tumors2Hereditary Multiple Osteochondromas1Patellofemoral Osteoarthritis1Functional Recovery1Reliability1Malignant Bone Tumor1

By trial register

Register	Trials	Recruiting
Clinical trials in Italy	108	92

A trial with sites in more than one country appears in each of those registers; recruiting counts cover the trials listed on this page.

Other sponsors in Knee Osteoarthritis

Sponsor	Trials
McMaster University	3
Helse Møre og Romsdal HF	3
CEN Biotech	2
Sahlgrenska University Hospital	2
Spaarne Gasthuis	2
Mardin Artuklu University	2
Össur Iceland ehf	1
Merit Medical Systems	1
Medipost	1
Pacira Pharmaceuticals	1

Sponsors with the most current trials registered for this condition.

Questions about Istituto Ortopedico Rizzoli trials

How many clinical trials does Istituto Ortopedico Rizzoli sponsor?

Istituto Ortopedico Rizzoli is the lead sponsor of 108 current trials on ClinicalTrials.gov in our Italy register, as of the registry sync on 12 November 2026. Completed and withdrawn studies are not counted.

Are Istituto Ortopedico Rizzoli trials recruiting?

Yes. 92 of its 108 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Istituto Ortopedico Rizzoli testing?

Its current trials name 5 drugs and biologicals as interventions. The most frequent are Bleomycin (1), Bone marrow aspirate (1), Leukocyte-Poor Platelet-Rich Plasma (1), Lr-Prp (1) and Metformin Hydrochloride (1). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, lead sponsor, phase, overall status, start date, conditions and intervention names
EU Clinical Trials Information System (CTIS) ↗ EU trial numbers, titles, sponsor, phase, status, therapeutic area and member-state countries

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 12 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.