dual energy x-ray absorptiometry: Patient will undergo periodic (6-12-24m) dexa scans on the periprosthetic bone
Study summary
compare changes in BMD via DXA at the level of the femoral and tibial periprosthetic bone between two groups of patients undergoing cemented TKA of different design (posterior stabilization vs posterior cruciate preservation) with proms at a 2-year follow-up.
Eligibility
Sex
ALL
Min age
45 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
1. Patients aged ≥ 45 years
2. Patients who are candidates for primary cemented total knee replacement based on physical examination and medical history, including diagnosis of severe knee pain and disability due to at least one of the following:
to. Primary or secondary osteoarthritis b. Collagen disorders and/or avascular necrosis of the femoral condyle c. Moderate valgus, varus or flexion deformities (HKA within ±10°, flexion contracture \<10°) 3. Patients consenting and able to complete planned study procedures and follow-up assessments 4. Patients informed about the nature of the study who signed the "informed consent" approved by the ethics committee.
Exclusion Criteria:
1. Patients aged \< 45 years;
2. Patients who have already undergone hip or knee arthroplasty ankle, previous osteotomy, with severe axial deformities or suffering from rheumatoid arthritis, diabetes or neuromuscular diseases. In this way, homogeneity of the investigated cohort will be guaranteed;
3. Pregnant women. -
Primary outcome measure(s)
Periprosthetic bone mineral density measurement — at baseline (day 0) measurement of periprosthetic bone mineral density using dual-energy x-ray absorptiometry
Periprosthetic bone mineral density measurement — 6 months measurement of periprosthetic bone mineral density using dual-energy x-ray absorptiometry
Periprosthetic bone mineral density measurement — 12 months measurement of periprosthetic bone mineral density using dual-energy x-ray absorptiometry
Periprosthetic bone mineral density measurement — 24 months measurement of periprosthetic bone mineral density using dual-energy x-ray absorptiometry
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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